Product image of Paracetamol Ab (Paracetamol) supplied by GNH India

Paracetamol Ab

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol Ab (Paracetamol)

Paracetamol, the active ingredient in Paracetamol Ab, is a non‑opioid analgesic and antipyretic presented as a standard oral tablet for oral use. It reduces fever and alleviates mild to moderate pain in adults and children when appropriate dosing is applied.

GNH India supplies Paracetamol Ab as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides reliable logistics for bulk and individual orders. Customers benefit from consistent product quality, regulatory compliance, and responsive technical support.

Manufacturer / TM Owner

Aurobindo N.V.

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Indications & Clinical Uses

Paracetamol is an analgesic and antipyretic used to manage pain and fever across various conditions.

  • Headache: provides relief from tension‑type and mild migraine headaches
  • Fever: reduces elevated body temperature in infections and inflammatory states
  • Musculoskeletal pain: alleviates mild to moderate pain from strains, sprains and backache
  • Dental pain: eases discomfort following dental procedures
  • Cold and flu symptoms: helps control fever and body aches associated with viral upper respiratory infections

How It Works

  • Paracetamol exerts its effect primarily by inhibiting the cyclooxygenase (COX) enzymes in the central nervous system, especially COX‑2, which reduces the synthesis of prostaglandins involved in pain and temperature regulation. It also acts on the hypothalamic heat‑regulation center to produce antipyretic effects, while peripheral COX inhibition is minimal, accounting for its low anti‑inflammatory activity.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea or mild stomach upset
  • Headache
  • Skin rash or mild itching
  • Dizziness

Serious or Rare Side Effects

  • Severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Hepatotoxicity, especially with overdose or chronic high‑dose use
  • Anaphylactic reactions
  • Blood disorders such as thrombocytopenia or agranulocytosis

Precautions & Warnings

Safe use of Paracetamol requires attention to several precautionary measures.

  • Dosage adjustment: reduce dose in patients with hepatic impairment
  • Avoid exceeding the recommended daily maximum dose to prevent liver injury
  • Limit alcohol consumption while using the product to reduce hepatotoxic risk
  • Pregnancy and lactation: consult a healthcare professional before use
  • Drug interactions: review concomitant medications for potential interactions
  • Store at ambient temperature: keep in the original pack, protect from moisture

Avoid Interactions

Paracetamol may interact with other medicines, necessitating careful management.

Major Interactions (Avoid)

  • Concurrent use with other paracetamol‑containing products: risk of overdose
  • Strong CYP450 inducers (e.g., rifampicin): may reduce analgesic efficacy
  • Warfarin: may enhance anticoagulant effect and increase bleeding risk
  • Alcohol: combined use heightens potential for hepatotoxicity

Moderate Interactions (Monitor Closely)

  • Isoniazid: may increase risk of liver toxicity
  • Carbamazepine: may affect paracetamol metabolism
  • Antiepileptics such as phenytoin: may alter plasma levels of either drug

Frequently Asked Questions

Paracetamol Ab is a generic paracetamol tablet indicated for the relief of mild to moderate pain such as headache, toothache, musculoskeletal discomfort, and for the reduction of fever associated with infections or inflammatory conditions. It is commonly used in both adult and pediatric populations when appropriate dosing is prescribed.

Paracetamol works by inhibiting cyclooxygenase enzymes, mainly COX‑2, within the central nervous system. This reduces the formation of prostaglandins that mediate pain and fever. Its action on the hypothalamic heat‑regulation center lowers body temperature, while peripheral anti‑inflammatory activity remains minimal.

The specific dose of Paracetamol Ab is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and overall health status. Typical adult regimens do not exceed 4 g per day, but exact dosing must follow the prescriber’s instructions.

Paracetamol is generally considered compatible with pregnancy and lactation when used at recommended doses, but it should only be taken after consulting a qualified healthcare provider. The prescriber will weigh potential benefits against any risks to the mother and infant.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

The primary alternative to paracetamol is non‑steroidal anti‑inflammatory drugs (NSAIDs) such as ibuprofen. Unlike NSAIDs, paracetamol has minimal anti‑inflammatory activity and does not irritate the gastric lining, making it preferable for patients at risk of gastrointestinal bleeding. However, NSAIDs may provide stronger anti‑inflammatory effects, while paracetamol carries a lower risk of renal impairment.

Paracetamol Ab tablets should be stored at ambient temperature, below 25 °C, in their original packaging to protect from moisture and light. Keep the product out of reach of children and avoid storing in areas with high humidity or direct sunlight.

Paracetamol Ab is administered orally. The tablet is swallowed whole with a glass of water. It can be taken with or without food, and the exact timing relative to meals should follow the prescriber’s guidance.

The most serious risks include hepatotoxicity, which can occur with overdose or chronic high‑dose use, and rare severe skin reactions such as Stevens‑Johnson syndrome. Prompt medical attention is required if signs of liver injury (e.g., jaundice, dark urine) or severe rash develop.

Paracetamol Ab should be avoided in individuals with known hypersensitivity to paracetamol or any excipients in the tablet, in patients with severe liver disease, and in those who have already reached the maximum daily dose of paracetamol from other sources. Pregnant or nursing women should only use it under medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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