Product image of Paracetamol Accord (Paracetamol) supplied by GNH India

Paracetamol Accord

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol Accord (Paracetamol)

Paracetamol, the active ingredient in Paracetamol Accord, is an analgesic and antipyretic presented as a tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children.

GNH India supplies Paracetamol Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Accord Healthcare B.V.

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Indications & Clinical Uses

Paracetamol is an analgesic and antipyretic used to manage pain and fever across various conditions.

  • Headache: provides relief from tension‑type headaches.
  • Fever: reduces elevated body temperature.
  • Musculoskeletal pain: alleviates mild to moderate pain from strains or sprains.
  • Dental pain: eases discomfort after dental procedures.
  • Cold symptoms: helps control fever and aches associated with the common cold.

How It Works

  • Paracetamol exerts its effect primarily by inhibiting the cyclooxygenase (COX) enzymes in the central nervous system, especially COX‑2, leading to reduced synthesis of prostaglandins that mediate pain and fever. Its action is largely peripheral independent, allowing antipyretic and analgesic activity without significant anti‑inflammatory effects.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild stomach upset.
  • Abdominal discomfort: occasional stomach pain.
  • Rash: skin redness or itching.
  • Headache: paradoxical headache in some users.

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome: severe skin reaction.
  • Hepatic failure: liver injury, especially with overdose.
  • Blood dyscrasias: rare blood cell abnormalities.
  • Anaphylaxis: life‑threatening allergic reaction.

Precautions & Warnings

Paracetamol should be used with attention to specific safety considerations.

  • Liver function: avoid use in severe hepatic impairment.
  • Alcohol consumption: limit alcohol as it may increase liver toxicity.
  • Dosage limits: do not exceed the recommended total daily dose.
  • Age restrictions: use lower doses in children according to weight.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Paracetamol can interact with several medicines, requiring monitoring.

Major Interactions (Avoid)

  • Warfarin: increased anticoagulant effect, risk of bleeding.
  • Isoniazid: heightened risk of hepatotoxicity.
  • Carbamazepine: reduced paracetamol clearance, lowering efficacy.

Moderate Interactions (Monitor Closely)

  • Alcohol: additive liver stress, especially with chronic use.
  • Phenytoin: may increase hepatic enzyme activity, affecting metabolism.
  • Phenobarbital: may reduce paracetamol effectiveness through enzyme induction.

Frequently Asked Questions

Paracetamol Accord contains paracetamol, an analgesic and antipyretic used to relieve mild to moderate pain such as headaches, musculoskeletal aches, dental discomfort, and to reduce fever associated with infections or other conditions.

Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which reduces the production of prostaglandins that signal pain and raise body temperature, thereby providing analgesic and antipyretic effects.

The appropriate dose of Paracetamol Accord is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and any relevant medical history. Patients should follow the prescriber’s instructions exactly.

Paracetamol is generally considered compatible with pregnancy and lactation when used at recommended doses, but a healthcare professional should evaluate the risk‑benefit profile for each individual before use.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Paracetamol offers analgesic and antipyretic benefits without the anti‑inflammatory activity of NSAIDs, making it suitable for patients who need pain relief but must avoid gastric irritation or platelet effects. Compared with opioids, it has a lower risk of dependence and sedation.

Paracetamol Accord should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children.

Paracetamol Accord is supplied as an oral tablet that should be swallowed whole with water. It may be taken with or without food, according to the prescriber’s guidance.

Serious risks include severe liver injury, especially with overdose or in patients with pre‑existing liver disease, and rare hypersensitivity reactions such as Stevens‑Johnson syndrome or anaphylaxis. Prompt medical attention is required if any signs of liver dysfunction or allergic reaction appear.

Paracetamol Accord should be avoided in individuals with known hypersensitivity to paracetamol, in patients with severe hepatic impairment, and in those who have exceeded the recommended daily dose. Consultation with a healthcare professional is essential for any contraindications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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