Product image of Paracetamol Accord (Paracetamol) supplied by GNH India

Paracetamol Accord

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol Accord (Paracetamol)

Paracetamol, the active ingredient in Paracetamol Accord, is an analgesic/antipyretic presented as an oral tablet for oral use. It provides relief from mild to moderate pain and reduces fever in adults and children.\n\nGNH India supplies Paracetamol Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Accord Healthcare B.V.

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Indications & Clinical Uses

  • Paracetamol is an analgesic and antipyretic that reduces pain and fever by acting on the central nervous system.\n\n- Mild to moderate pain: provides relief from headaches, musculoskeletal discomfort, dental pain and other common aches.\n- Fever: lowers elevated body temperature associated with infections, inflammatory conditions or other causes.\n- Cold and flu symptoms: alleviates associated aches, sore throat discomfort and fever during upper respiratory infections.

How It Works

  • Paracetamol works primarily by inhibiting the cyclooxygenase (COX) enzymes, especially COX‑2, within the central nervous system. This reduces the synthesis of prostaglandins that mediate pain and fever signals, leading to analgesic and antipyretic effects without significant peripheral anti‑inflammatory activity.

Side Effects

  • Paracetamol is generally well tolerated, but adverse reactions can occur.\n\nCommon Side Effects:\n- Nausea: mild stomach upset that may accompany dosing.\n- Skin rash: occasional mild erythema or itching.\n- Elevated liver enzymes: transient increases detectable in laboratory tests.\n- Headache: paradoxical headache in a small number of users.\n\nSerious or Rare Side Effects:\n- Hepatotoxicity: severe liver injury, especially with overdose or chronic high‑dose use.\n- Stevens‑Johnson syndrome: rare severe skin reaction requiring immediate medical attention.\n- Anaphylaxis: extremely rare allergic reaction with breathing difficulty and swelling.

Precautions & Warnings

  • Paracetamol should be used with awareness of specific safety considerations.\n\n- Dose limitation: do not exceed the maximum daily amount recommended by a healthcare professional.\n- Liver disease: avoid or use only under strict medical supervision if hepatic impairment is present.\n- Alcohol consumption: limit intake as concurrent alcohol use can increase liver toxicity risk.\n- Pregnancy: consult a physician; generally considered safe when prescribed, but professional guidance is essential.\n- Pediatric use: ensure appropriate formulation and dosing for children; follow prescriber instructions.\n- Store at ambient temperature: keep below 25°C, retain in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

  • Paracetamol may interact with other medicines, altering its efficacy or safety profile.\n\nMajor Interactions (Avoid):\n- Warfarin: increased anticoagulant effect may raise bleeding risk.\n- High‑dose ibuprofen or other NSAIDs: combined use can heighten liver toxicity.\n\nModerate Interactions (Monitor Closely):\n- Antiepileptic drugs (e.g., carbamazepine, phenytoin): may reduce paracetamol plasma levels.\n- Rifampicin: may increase metabolism, lowering effectiveness.\n- Alcohol: chronic consumption can potentiate hepatotoxicity.

Frequently Asked Questions

Paracetamol Accord is used to relieve mild to moderate pain such as headaches, muscle aches, dental pain, and to reduce fever associated with infections or other causes. It is an oral analgesic and antipyretic commonly employed in both adult and pediatric populations under medical guidance.

Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which reduces the production of prostaglandins that signal pain and fever. This central action provides analgesic and antipyretic effects without significant anti‑inflammatory activity at typical therapeutic doses.

The appropriate dose of Paracetamol Accord is determined by a qualified prescriber based on the patient’s age, weight, clinical condition, and local regulatory guidelines. Patients should follow the exact dosing instructions provided by their healthcare professional and not exceed the recommended maximum daily amount.

Paracetamol is generally considered safe for short‑term use during pregnancy and breastfeeding when prescribed by a healthcare professional. However, pregnant or lactating individuals should always consult their physician before starting any medication to ensure it is appropriate for their specific situation.

To order Paracetamol Accord, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. The team then provides pricing, availability, shipping details (including any cold‑chain requirements), and assists with import documentation.

Paracetamol differs from non‑steroidal anti‑inflammatory drugs (NSAIDs) such as ibuprofen by lacking significant peripheral anti‑inflammatory activity and having a lower risk of gastrointestinal irritation. It is often preferred when NSAIDs are contraindicated, but it does not provide the same anti‑inflammatory benefits and requires careful dosing to avoid liver toxicity.

Paracetamol Accord should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in their original packaging, protect them from moisture, direct sunlight, and excessive heat. Ensure the container is tightly closed to maintain product stability throughout its shelf life.

Paracetamol Accord is administered orally as a tablet. It should be swallowed whole with water, unless a specific formulation (e.g., chewable or liquid) is prescribed. The exact administration schedule, including timing and frequency, is determined by the prescribing clinician.

The most serious risk is hepatotoxicity, which can occur with overdose or chronic high‑dose use, potentially leading to liver failure. Rare but severe allergic reactions such as Stevens‑Johnson syndrome or anaphylaxis may also occur. Prompt medical attention is required if signs of liver injury or severe hypersensitivity appear.

Paracetamol Accord should be avoided by individuals with known hypersensitivity to paracetamol or any excipients in the tablet, patients with severe liver disease unless specifically directed by a physician, and those who have exceeded the recommended daily dose. Pregnant or breastfeeding women should consult a healthcare provider before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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