Paracetamol/Ass/Coffein Kopfschmerz & Migräne Haleon Germany (Paracetamol, Acetylsalicylic Acid, Caffeine)

Paracetamol reduces central pain signalling by inhibiting cyclooxygenase enzymes in the brain, acetylsalicylic acid blocks peripheral cyclooxygenase‑1 and‑2 to lower prostaglandin production, and caffeine antagonises adenosine receptors, which enhances the analgesic effect and causes mild vasoconstriction that can alleviate headache‑related vascular dilation.

The appropriate dose is determined by the prescribing healthcare professional based on the patient’s condition, age, weight and other medications. The prescriber will specify the exact amount and frequency on the prescription label.

Use during pregnancy or lactation should only occur under medical advice. Paracetamol is generally considered low risk, but the aspirin component may affect fetal development and platelet function, and caffeine exposure is also a consideration. A healthcare provider will evaluate the risk‑benefit profile for each individual.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Compared with single‑ingredient analgesics such as paracetamol alone, the combination adds aspirin’s anti‑inflammatory action and caffeine’s analgesic‑enhancing effect, often providing faster and more complete relief for moderate headache pain. It is generally considered more potent than paracetamol or aspirin alone, but it also carries a broader safety profile.

Store the tablets at ambient temperature, preferably below 25 °C, in the original blister pack or container. Protect them from moisture, excessive heat and direct sunlight to maintain potency.

The medication is taken orally with a glass of water. It may be taken with or without food, although taking it with food can reduce the chance of stomach irritation.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, liver toxicity especially with overdose, and impaired kidney function. Patients with a history of ulcers, bleeding disorders or liver disease should be monitored closely.

Individuals with known hypersensitivity to paracetamol, aspirin or caffeine, active peptic ulcer disease, uncontrolled bleeding disorders, severe liver or kidney impairment, and children under the recommended age should avoid this product unless directed by a physician.