Product image of Paracetamol And Caffeine Socium Pharma B.V. (Paracetamol, Caffeine) supplied by GNH India

Paracetamol And Caffeine Socium Pharma B.V.

Active Ingredient:
Paracetamol, Caffeine
Origin:
EU

Paracetamol And Caffeine Socium Pharma B.V. (Paracetamol, Caffeine)

Paracetamol, the active ingredient in Paracetamol And Caffeine Socium Pharma B.V., is an analgesic, antipyretic and central nervous system stimulant presented as an oral tablet for oral use. It treats headache, fever, minor musculoskeletal pain and dental pain in adults and children.

GNH India supplies Paracetamol And Caffeine Socium Pharma B.V. as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Socium Pharma Bv

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Indications & Clinical Uses

  • Paracetamol and caffeine act on pain and fever pathways to provide symptomatic relief.
  • Headache: reduces pain and discomfort.
  • Fever: lowers elevated body temperature.
  • Minor musculoskeletal pain: alleviates pain and improves function.
  • Dental pain: relieves pain associated with dental procedures.

How It Works

  • Paracetamol acts centrally to inhibit cyclooxygenase enzymes, decreasing prostaglandin synthesis and producing analgesic and antipyretic effects. Caffeine antagonizes adenosine receptors, providing mild central nervous system stimulation and enhancing the analgesic effect of paracetamol through increased absorption and reduced perception of pain.

Side Effects

Paracetamol and caffeine are generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild stomach upset after ingestion.
  • Insomnia: difficulty falling or staying asleep.
  • Stomach upset: dyspepsia or mild abdominal discomfort.
  • Headache: paradoxical headache in some individuals.

Serious or Rare Side Effects

  • Allergic reactions: rash, swelling, or difficulty breathing.
  • Liver injury: rare but possible with overdose or pre‑existing liver disease.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

  • Paracetamol and caffeine should be used with caution in certain situations.
  • Assess liver function: avoid in patients with severe hepatic impairment.
  • Limit alcohol consumption: concurrent use may increase liver risk.
  • Monitor caffeine intake: avoid excessive caffeine from other sources.
  • Use with caution in pregnancy: safety not established.
  • Avoid in children under 12 without medical advice.
  • Store at ambient temperature: keep in original container, protect from moisture.

Avoid Interactions

Paracetamol and caffeine may interact with other medicines; some interactions require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Alcohol: increased risk of liver toxicity.
  • Anticoagulants (e.g., warfarin): may enhance bleeding risk.
  • Certain anticonvulsants (e.g., carbamazepine): may reduce paracetamol efficacy.
  • Monoamine oxidase inhibitors: risk of hypertension.

Moderate Interactions (Monitor Closely)

  • CYP450 inducers (e.g., rifampicin): may lower plasma levels.
  • CYP450 inhibitors (e.g., fluconazole): may increase plasma levels.
  • Other CNS stimulants: may increase insomnia or nervousness.

Frequently Asked Questions

Paracetamol and caffeine is an over‑the‑counter oral product used to relieve mild to moderate pain such as headache, fever, minor musculoskeletal discomfort and dental pain. The combination provides analgesic and antipyretic effects, making it suitable for short‑term symptomatic relief in adults and children when appropriate.

Paracetamol works by centrally inhibiting cyclooxygenase enzymes, which reduces the synthesis of prostaglandins that mediate pain and fever. This action provides analgesic and antipyretic effects without significant anti‑inflammatory activity.

The specific dose of Paracetamol and Caffeine is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition and other medications. The prescriber will set the appropriate strength and frequency according to local guidelines.

Safety data for this combination in pregnancy and lactation are limited. Healthcare providers usually weigh the potential benefits against possible risks before prescribing. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their doctor.

To request Paracetamol and Caffeine, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

The addition of caffeine to paracetamol can enhance pain relief by up to 40 % in some studies, especially for headache and musculoskeletal pain. Caffeine also counteracts drowsiness that may accompany paracetamol alone, but it introduces considerations such as potential insomnia and interactions with other stimulants.

Store the product at ambient temperature, preferably below 25 °C. Keep it in the original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

Paracetamol and caffeine is taken orally, usually with a glass of water. It can be taken with or without food, but patients who experience stomach upset may prefer taking it with a small amount of food.

Serious risks, although rare, include severe allergic reactions (rash, swelling, breathing difficulty), liver injury especially in cases of overdose or pre‑existing liver disease, and rare severe skin reactions such as Stevens‑Johnson syndrome. Patients should seek immediate medical attention if any of these occur.

Individuals with known hypersensitivity to paracetamol, caffeine or any excipients, patients with severe hepatic impairment, children under 12 years old without medical supervision, and those who are pregnant or breastfeeding without a doctor’s advice should avoid using this product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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