Product image of Paracetamol Aristo (Paracetamol) supplied by GNH India

Paracetamol Aristo

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol Aristo (Paracetamol)

Paracetamol, the active ingredient in Paracetamol Aristo, is an analgesic and antipyretic presented as an oral tablet for oral use. It treats mild to moderate pain and reduces fever in adults and children.
GNH India supplies Paracetamol Aristo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aristo Pharma Iberia, S.L.

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Indications & Clinical Uses

  • Paracetamol is an analgesic and antipyretic that reduces pain and fever by acting on the central nervous system.
  • Headache: provides relief of mild to moderate headache pain.
  • Fever: lowers elevated body temperature.
  • Musculoskeletal pain: alleviates pain associated with strains, sprains and backache.
  • Toothache: eases dental pain.
  • Menstrual cramps: helps relieve dysmenorrhea.

How It Works

  • Paracetamol inhibits central cyclooxygenase (COX) enzymes, primarily COX‑2, leading to reduced synthesis of prostaglandins in the brain and spinal cord. This modulation diminishes the perception of pain and lowers the hypothalamic set‑point for temperature regulation, providing analgesic and antipyretic effects without significant peripheral anti‑inflammatory activity.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea
  • Vomiting
  • Stomach discomfort or dyspepsia
  • Mild skin rash
  • Transient elevation of liver enzymes

Serious or Rare Side Effects

  • Anaphylaxis or severe allergic reaction
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Acute liver failure or severe hepatotoxicity
  • Blood disorders such as agranulocytosis or thrombocytopenia

Precautions & Warnings

  • Paracetamol should be used with attention to specific safety considerations.
  • Dosage adjustment: required in patients with hepatic impairment.
  • Alcohol consumption: avoid or limit due to increased risk of liver injury.
  • Concurrent use with other paracetamol‑containing products: avoid duplication to prevent overdose.
  • Use in children: follow pediatric dosing guidelines and age‑appropriate formulations.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Paracetamol may interact with several medicines; some require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Warfarin: increased anticoagulant effect, heightened bleeding risk.
  • Isoniazid: combined use raises potential for hepatotoxicity.
  • Carbamazepine: may reduce paracetamol clearance, leading to toxicity.

Moderate Interactions (Monitor Closely)

  • Alcohol: additive risk of liver damage.
  • Other hepatotoxic drugs (e.g., halothane): monitor liver function tests.
  • Enzyme inducers (e.g., rifampicin): may lower paracetamol efficacy.

Frequently Asked Questions

Paracetamol Aristo is used to relieve mild to moderate pain such as headache, toothache, muscle aches, and to reduce fever. It is an over‑the‑counter analgesic and antipyretic commonly employed in both adult and pediatric populations for symptomatic relief.

Paracetamol works by inhibiting central cyclooxygenase enzymes, which reduces the production of prostaglandins in the brain and spinal cord. This action lowers the perception of pain and resets the hypothalamic temperature set‑point, thereby providing analgesic and antipyretic effects.

The appropriate dose of Paracetamol Aristo is determined by a prescriber based on the patient’s age, weight, and clinical condition. Dosage instructions are provided on the product label and should be followed exactly as directed by a healthcare professional.

Safety of paracetamol during pregnancy or lactation should be evaluated by a healthcare provider. While paracetamol is generally considered low risk, the prescriber will weigh potential benefits against any possible risks before recommending use.

To order Paracetamol Aristo, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Paracetamol differs from non‑steroidal anti‑inflammatory drugs (NSAIDs) by providing analgesic and antipyretic effects without significant anti‑inflammatory activity or gastrointestinal irritation. It is often chosen when NSAIDs are contraindicated, but it lacks the anti‑inflammatory benefits that ibuprofen or naproxen provide.

Paracetamol Aristo should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and sources of heat to maintain its stability and potency.

Paracetamol Aristo is taken orally, usually as a tablet, with or without water. It can be taken with food or on an empty stomach, but patients should follow the dosing schedule recommended by their prescriber.

The most serious risks include severe allergic reactions such as anaphylaxis, rare skin conditions like Stevens‑Johnson syndrome, and potentially life‑threatening liver injury, especially when taken in excess or combined with other hepatotoxic substances.

Individuals with known hypersensitivity to paracetamol, severe liver disease, or those who regularly consume high amounts of alcohol should avoid using Paracetamol Aristo. Additionally, patients taking other medications containing paracetamol should not use this product without medical guidance.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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