Product image of Paracetamol Aurobindo (Paracetamol) supplied by GNH India

Paracetamol Aurobindo

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol Aurobindo (Paracetamol)

Paracetamol, the active ingredient in Paracetamol Aurobindo, is an analgesic presented as an oral tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children.

GNH India supplies Paracetamol Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aurobindo Pharma B.V.

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Indications & Clinical Uses

  • Paracetamol acts as an analgesic and antipyretic, addressing pain‑related and febrile pathways.
  • Pain: provides relief of mild to moderate nociceptive pain.
  • Fever: lowers elevated body temperature.
  • Headache: alleviates tension‑type headache.
  • Dental pain: helps manage postoperative dental discomfort.
  • Osteoarthritis: assists in reducing joint pain associated with osteoarthritis.

How It Works

  • Paracetamol exerts its effect by inhibiting cyclooxygenase enzymes in the central nervous system, which reduces the synthesis of prostaglandins. The lowered prostaglandin levels diminish the perception of pain and reset the hypothalamic set‑point for temperature regulation, thereby providing analgesic and antipyretic actions.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild gastrointestinal upset.
  • Abdominal discomfort: transient stomach pain.
  • Rash: mild skin irritation.
  • Elevated liver enzymes: usually reversible.
  • Dizziness: occasional light‑headedness.

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome: severe skin reaction.
  • Hepatic failure: rare but potentially life‑threatening liver injury.
  • Blood dyscrasias: such as agranulocytosis.
  • Anaphylaxis: acute allergic response.
  • Severe skin eruptions: including toxic epidermal necrolysis.

Precautions & Warnings

  • Paracetamol should be used with attention to specific safety considerations.
  • Dose adjustment in hepatic impairment: reduce dose in patients with liver disease.
  • Avoid in severe hepatic failure: contraindicated when liver function is markedly compromised.
  • Caution with alcohol use: concurrent intake may increase liver toxicity.
  • Do not exceed maximum daily dose: adhere to recommended total daily limits.
  • Monitor for allergic reactions: discontinue if rash or swelling develops.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Paracetamol may interact with other medicines, influencing efficacy or safety.

Major Interactions (Avoid)

  • Warfarin: increased anticoagulant effect, risk of bleeding.
  • Carbamazepine: enhanced metabolism, reduced analgesic effect.
  • Rifampicin: induces hepatic enzymes, lowering plasma levels.
  • Phenobarbital: similar enzyme induction, decreasing effectiveness.
  • Lithium: may increase plasma lithium concentrations.

Moderate Interactions (Monitor Closely)

  • Alcohol: additive hepatotoxic risk.
  • Isoniazid: potential for increased liver enzyme elevation.
  • Oral contraceptives: may slightly reduce analgesic efficacy.
  • Antiepileptics (e.g., phenytoin): may alter drug levels.
  • High‑dose vitamin C: possible competition for metabolism.

Frequently Asked Questions

Paracetamol Aurobindo is used to relieve mild to moderate pain such as headache, dental pain, musculoskeletal discomfort, and to reduce fever. It belongs to the analgesic and antipyretic class, making it suitable for a wide range of short‑term symptomatic treatments in both adults and children.

Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which lowers the production of prostaglandins. This reduction diminishes the brain’s perception of pain and resets the hypothalamic temperature set‑point, resulting in analgesic and antipyretic effects.

The appropriate dose of Paracetamol Aurobindo is determined by a qualified prescriber based on the patient’s age, weight, clinical condition, and any underlying health issues. Healthcare professionals follow local guidelines and product labeling to set the correct dosing regimen.

Safety data for paracetamol in pregnancy and lactation are limited, and the product’s pregnancy category is listed as unknown. Clinicians generally weigh the benefits against potential risks and may recommend alternative therapies if safer options are available.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Paracetamol primarily provides analgesic and antipyretic effects with minimal anti‑inflammatory activity, whereas ibuprofen adds anti‑inflammatory properties. Ibuprofen may cause more gastrointestinal irritation, while paracetamol is generally gentler on the stomach but requires careful dosing in patients with liver impairment.

Paracetamol Aurobindo should be stored at room temperature, below 25 °C, in its original packaging. The container should be kept away from moisture and direct sunlight to maintain product stability throughout its shelf life.

Paracetamol Aurobindo is administered orally. The tablet is swallowed whole with water and can be taken with or without food, following the dosing instructions provided by the prescriber or the product label.

The most serious risks include severe liver injury, especially when exceeding the maximum daily dose or combining with alcohol, and rare hypersensitivity reactions such as Stevens‑Johnson syndrome or anaphylaxis. Prompt medical attention is required if signs of liver dysfunction or severe skin reactions appear.

Paracetamol Aurobindo should be avoided in individuals with known hypersensitivity to paracetamol, those with severe hepatic failure, and patients who are unable to adhere to the recommended maximum daily dose. Clinicians should also assess risk in patients with chronic alcohol use or existing liver disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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