Product image of Paracetamol Aurobindo Pharma (Paracetamol) supplied by GNH India

Paracetamol Aurobindo Pharma

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol Aurobindo Pharma (Paracetamol)

Paracetamol, the active ingredient in Paracetamol Aurobindo Pharma, is an analgesic presented as an oral dosage form for systemic use. It is used to relieve fever and mild to moderate pain in adults and children when appropriate dosing is applied.

GNH India supplies Paracetamol Aurobindo Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for each batch. Its distribution network covers Europe, Asia, Africa and the Americas, ensuring timely delivery to authorized buyers.

Manufacturer / TM Owner

Aurobindo Pharma B.V.

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Indications & Clinical Uses

  • Paracetamol acts centrally to reduce fever and alleviate mild to moderate pain.
  • Fever: Lowers elevated body temperature by acting on the hypothalamic heat‑regulation center.
  • Headache: Relieves tension‑type or mild migraine headache symptoms.
  • Musculoskeletal pain: Decreases discomfort associated with strains, sprains or backache.

How It Works

  • Paracetamol inhibits cyclooxygenase (COX) enzymes, primarily COX‑2, within the central nervous system, leading to reduced synthesis of prostaglandins that mediate pain and fever. The peripheral anti‑inflammatory effect is minimal, which distinguishes it from non‑steroidal anti‑inflammatory drugs. Its action on the hypothalamic thermoregulatory center also contributes to antipyretic activity.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild stomach upset.
  • Skin rash: transient erythema.
  • Elevated liver enzymes: mild, reversible.
  • Dizziness: occasional light‑headedness.

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome: severe skin blistering.
  • Anaphylactic reaction: sudden airway swelling.
  • Acute liver failure: marked transaminase rise, jaundice.
  • Blood dyscrasias: thrombocytopenia or neutropenia.

Precautions & Warnings

Paracetamol should be used with caution in certain populations and clinical situations.

  • Dose adjustment: Reduce dose in patients with hepatic impairment.
  • Alcohol use: Avoid excessive alcohol as it increases hepatotoxic risk.
  • Concomitant hepatotoxic drugs: Monitor liver function when combined with other liver‑affecting agents.
  • Pregnancy: Use only if clearly needed after risk‑benefit assessment.
  • Age: Use lower doses in children according to weight‑based guidelines.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Paracetamol can interact with several medicines; some require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Warfarin: Paracetamol may potentiate anticoagulant effect, increasing bleeding risk.
  • Isoniazid: Combined use can raise risk of liver injury.
  • Highly hepatotoxic drugs (e.g., halothane): Concurrent use may cause severe hepatotoxicity.

Moderate Interactions (Monitor Closely)

  • Alcohol: Increases risk of liver damage; advise limited intake.
  • Carbamazepine: May reduce paracetamol plasma levels, diminishing efficacy.
  • Phenytoin: May increase paracetamol metabolism, requiring monitoring.

Frequently Asked Questions

Paracetamol Aurobindo Pharma is used to reduce fever and to relieve mild to moderate pain such as headache, toothache, muscle aches, and joint discomfort. It is an over‑the‑counter analgesic/antipyretic that works systemically after oral administration.

Paracetamol works by inhibiting central cyclooxygenase enzymes, especially COX‑2, which lowers the production of prostaglandins in the brain. This reduction diminishes the perception of pain and resets the hypothalamic set‑point for body temperature, producing analgesic and antipyretic effects.

The specific dose of Paracetamol Aurobindo Pharma is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and any existing medical issues. Adults typically receive up to 1 g per dose, not exceeding 4 g per day, but exact dosing must follow the prescriber’s instructions.

Paracetamol is generally considered compatible with pregnancy and lactation when used at the lowest effective dose for the shortest duration. Nevertheless, a healthcare provider should evaluate the risk‑benefit profile for each individual, especially in the first trimester or when other medications are being taken.

To place an order, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Paracetamol provides analgesic and antipyretic effects with minimal anti‑inflammatory activity, whereas ibuprofen is a non‑steroidal anti‑inflammatory drug that also reduces inflammation. Ibuprofen carries a higher risk of gastrointestinal irritation and renal effects, while paracetamol has a greater potential for liver toxicity at excessive doses. Choice depends on the clinical need and patient tolerance.

Store the product at ambient temperature, preferably below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight, and sources of heat. Ensure the container is tightly closed to maintain product stability throughout its shelf life.

Paracetamol Aurobindo Pharma is administered orally. The tablet (or other oral dosage form) should be swallowed whole with water, unless the label advises otherwise. It can be taken with or without food, but patients should follow the dosing schedule prescribed by their healthcare professional.

The most serious risks include severe liver injury, especially when doses exceed recommended limits or when combined with other hepatotoxic agents, and rare hypersensitivity reactions such as Stevens‑Johnson syndrome or anaphylaxis. Prompt medical attention is required if signs of liver failure (jaundice, dark urine) or severe skin reactions develop.

Paracetamol should be avoided in individuals with known hypersensitivity to the drug, in patients with severe hepatic impairment, and in those who are concurrently using other medications that carry a high risk of liver toxicity unless closely monitored. Pregnant or breastfeeding women should only use it after professional medical advice.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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