Product image of Paracetamol B. Braun (Paracetamol) supplied by GNH India

Paracetamol B. Braun

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol B. Braun (Paracetamol)

Paracetamol, the active ingredient in Paracetamol B. Braun, is an analgesic presented as an injectable solution for intravenous use. It treats pain and fever in adult and pediatric patients as directed by a healthcare professional. Paracetamol works by inhibiting central cyclooxygenase enzymes, reducing prostaglandin synthesis and providing symptomatic relief.

GNH India supplies Paracetamol B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Paracetamol is an analgesic/antipyretic that reduces pain and fever by acting on the central nervous system.

  • Pain relief: provides symptomatic relief of mild to moderate pain.
  • Fever reduction: lowers elevated body temperature.
  • Post‑operative pain: helps manage discomfort after surgical procedures.
  • Headache: alleviates tension‑type and migraine‑associated headache.
  • Dental pain: reduces discomfort associated with dental procedures.

How It Works

  • Paracetamol exerts its effect primarily through inhibition of cyclooxygenase (COX) enzymes in the central nervous system, especially COX‑2, leading to decreased synthesis of prostaglandins that mediate pain and fever. The exact peripheral anti‑inflammatory activity is minimal, which distinguishes it from non‑steroidal anti‑inflammatory drugs.

Side Effects

Paracetamol may cause adverse reactions ranging from mild to severe.

Common Side Effects

  • Injection site pain: discomfort at the site of intravenous administration.
  • Nausea: mild gastrointestinal upset.
  • Dizziness: transient feeling of light‑headedness.
  • Flushing: temporary reddening of the skin.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Severe hepatic injury: potential liver damage, especially with overdose.
  • Stevens‑Johnson syndrome: rare but serious skin reaction.
  • Blood dyscrasias: abnormal blood cell counts.
  • Thrombophlebitis: inflammation of a vein with clot formation.

Precautions & Warnings

When using Paracetamol B. Braun, consider the following precautions.

  • Hepatic impairment: adjust dose or avoid in patients with severe liver disease.
  • Renal impairment: use with caution in patients with reduced kidney function.
  • Allergic reactions: monitor for signs of hypersensitivity, especially in patients with known paracetamol allergy.
  • Concomitant paracetamol products: avoid duplicate therapy to prevent overdose.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake the vial.

Avoid Interactions

Paracetamol can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Other paracetamol‑containing products: risk of cumulative overdose.
  • Hepatotoxic drugs (e.g., isoniazid, valproate): increased risk of liver injury.
  • Warfarin: may potentiate anticoagulant effect and raise INR.

Moderate Interactions (Monitor Closely)

  • Alcohol consumption: enhances hepatic toxicity.
  • CYP450 inducers (e.g., carbamazepine, rifampicin): may reduce paracetamol efficacy.
  • Certain anticonvulsants (e.g., phenytoin): may alter metabolism and require monitoring.

Frequently Asked Questions

Paracetamol B. Braun is an intravenous formulation of paracetamol used to provide rapid relief of mild to moderate pain and to reduce fever in hospital settings. It is commonly employed after surgery, for headache, dental pain, and other acute pain conditions where oral administration is not feasible.

Paracetamol works by inhibiting cyclooxygenase enzymes, especially COX‑2, within the central nervous system. This inhibition reduces the production of prostaglandins, which are mediators of pain and fever, thereby providing analgesic and antipyretic effects without significant anti‑inflammatory activity.

The dose of Paracetamol B. Braun is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and liver function. Healthcare professionals follow established dosing guidelines and adjust the regimen as needed for safety and efficacy.

Safety data for intravenous paracetamol during pregnancy and lactation are limited. It should only be used when the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and required import documentation.

Compared with other intravenous analgesics such as ibuprofen or opioid preparations, paracetamol offers effective pain and fever control with a lower risk of gastrointestinal irritation and respiratory depression. It is often used as part of multimodal analgesia to reduce opioid requirements.

Paracetamol B. Braun must be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. The vial should be kept in its original packaging until use to maintain sterility and stability.

The product is administered by a qualified healthcare professional as an intravenous injection. It may be given undiluted or diluted in compatible IV fluids, following aseptic technique and the prescribed infusion rate.

Serious risks include severe allergic reactions such as anaphylaxis, rare skin conditions like Stevens‑Johnson syndrome, and potential liver injury, especially with overdose or in patients with pre‑existing hepatic impairment. Prompt medical attention is required if any of these occur.

Paracetamol B. Braun should be avoided in individuals with known hypersensitivity to paracetamol or any excipients in the formulation, and in patients with severe liver disease. Caution is also advised for those with significant renal impairment or a history of severe allergic reactions to injectable medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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