Paracetamol B. Braun (Paracetamol)

Paracetamol works by inhibiting cyclooxygenase enzymes, mainly COX‑2, which decreases the production of prostaglandins. Lower prostaglandin levels reduce pain signaling in the nervous system and reset the hypothalamic temperature set‑point, producing analgesic and antipyretic effects.

The appropriate dose is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and severity of pain or fever. Dosing guidelines are provided in the product’s prescribing information and should be individualized for each patient.

Data on intravenous paracetamol use during pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made in consultation with a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Compared with intravenous non‑steroidal anti‑inflammatory drugs such as ibuprofen, paracetamol has a lower risk of gastrointestinal irritation and platelet inhibition, but it relies on hepatic metabolism and therefore requires careful use in patients with liver dysfunction.

Paracetamol B. Braun should be stored at ambient temperature, preferably below 25 °C. Keep the vials in their original packaging, protect them from moisture and direct light, and avoid freezing. Inspect the solution for particulate matter before administration.

The product is given by intravenous infusion. The prescribed volume is diluted in an appropriate compatible IV fluid and administered over the time period recommended in the prescribing information, typically ranging from a few minutes to an hour, depending on clinical need.

Serious risks include anaphylactic reactions, severe liver injury (hepatotoxicity) especially with overdose or pre‑existing liver disease, and rare severe skin reactions such as Stevens‑Johnson syndrome. Immediate medical attention is required if any of these events occur.

Paracetamol B. Braun is contraindicated in patients with known hypersensitivity to paracetamol or any excipients, and it should be avoided in individuals with severe hepatic impairment or active liver disease. Caution is also advised for patients with renal dysfunction or those taking other hepatotoxic medications.