Product image of Paracetamol B. Braun (Paracetamol) supplied by GNH India

Paracetamol B. Braun

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol B. Braun (Paracetamol)

Paracetamol, the active ingredient in Paracetamol B. Braun, is an analgesic presented as an oral dosage form for oral use. It provides relief from mild to moderate pain and reduces fever in adults and children when administered according to professional guidance. It is widely used in clinical practice for conditions such as headache, musculoskeletal pain, and postoperative discomfort.

GNH India supplies Paracetamol B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product complies with EU quality standards and is manufactured under GMP conditions.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Paracetamol is used as an analgesic and antipyretic to manage pain and fever across various clinical settings.

  • Headache: alleviates pain and improves comfort
  • Fever: lowers elevated body temperature
  • Musculoskeletal pain: reduces discomfort associated with strains and sprains

How It Works

  • Paracetamol exerts its effect primarily by inhibiting the cyclooxygenase (COX) enzymes in the central nervous system, which reduces the synthesis of prostaglandins involved in pain signaling and thermoregulation. This peripheral and central action leads to decreased perception of pain and a lowering of body temperature without significant anti‑inflammatory activity.

Side Effects

Paracetamol may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Nausea
  • Abdominal discomfort
  • Rash or mild skin irritation
  • Elevated liver enzymes (asymptomatic)

Serious or Rare Side Effects

  • Severe allergic reactions (anaphylaxis, angioedema)
  • Acute liver failure (especially with overdose)
  • Blood disorders such as thrombocytopenia
  • Severe skin reactions (Stevens‑Johnson syndrome)

Precautions & Warnings

When using Paracetamol, several safety considerations should be observed to minimize risk.

  • Assess liver function: avoid use in patients with severe hepatic impairment
  • Avoid alcohol: concurrent consumption may increase hepatotoxic risk
  • Use lowest effective dose: limit exposure to reduce adverse effects
  • Monitor dosing in children: dose should be weight‑based and supervised
  • Pregnancy and breastfeeding: consult a healthcare professional before use
  • Store at ambient temperature: keep in the original packaging, protect from moisture

Avoid Interactions

Paracetamol can interact with other medicines, affecting its safety or efficacy.

Major Interactions (Avoid)

  • Concurrent use with other hepatotoxic drugs (e.g., high‑dose isoniazid, methotrexate): increased risk of liver injury
  • Alcohol consumption: synergistic hepatotoxicity leading to liver damage

Moderate Interactions (Monitor Closely)

  • Warfarin: may enhance anticoagulant effect, requiring INR monitoring
  • Phenobarbital or carbamazepine: may increase paracetamol metabolism, reducing efficacy
  • Isoniazid: additive hepatic risk, monitor liver enzymes

Frequently Asked Questions

Paracetamol B. Braun is an analgesic and antipyretic medication used to relieve mild to moderate pain such as headache, muscle aches, and postoperative discomfort, and to reduce elevated body temperature caused by fever. It is commonly employed in both adult and pediatric patients under professional medical guidance.

Paracetamol works by inhibiting cyclooxygenase enzymes, primarily COX‑2, within the central nervous system. This inhibition reduces the production of prostaglandins that mediate pain and regulate body temperature, thereby providing analgesic and antipyretic effects without significant anti‑inflammatory activity.

The appropriate dose of Paracetamol B. Braun is determined by a qualified prescriber based on the patient’s age, weight, clinical condition, and overall health status. Healthcare professionals follow established dosing guidelines to ensure safe and effective therapy, and patients should follow the prescribed regimen exactly.

Paracetamol is generally considered compatible with pregnancy and breastfeeding when used at the lowest effective dose for short periods. However, pregnant or lactating individuals should consult their healthcare provider before starting therapy to confirm that it is appropriate for their specific situation.

To order Paracetamol B. Braun, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After verification of trade or institutional credentials, the sales team will provide pricing, availability, shipping details (including any cold‑chain requirements if applicable), and assist with import documentation.

Paracetamol and ibuprofen both relieve pain and reduce fever, but they differ in mechanisms and safety profiles. Paracetamol primarily acts centrally with minimal anti‑inflammatory effect, while ibuprofen is a non‑steroidal anti‑inflammatory drug (NSAID) that also reduces inflammation. Ibuprofen may cause gastrointestinal irritation and affect kidney function, whereas paracetamol carries a higher risk of liver toxicity, especially at excessive doses or with alcohol use.

Paracetamol should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments. No special refrigeration is required for oral dosage forms.

Paracetamol is administered orally, typically as tablets, capsules, or liquid suspensions. The medication is swallowed with water, and the dosage form is selected based on patient age and preference. It should be taken according to the prescriber’s instructions, and the tablets should not be crushed or chewed unless specifically advised.

The most serious risks of Paracetamol include acute liver failure, which can occur with overdose or when combined with other hepatotoxic agents, and severe allergic reactions such as anaphylaxis. Rare but severe skin reactions like Stevens‑Johnson syndrome may also develop. Prompt medical attention is required if any signs of liver dysfunction or severe hypersensitivity appear.

Paracetamol should be avoided in individuals with known hypersensitivity to the drug, severe hepatic impairment, or those who regularly consume excessive alcohol. Patients taking other hepatotoxic medications should consult a healthcare professional before use. Additionally, children under the recommended age for the specific dosage form should not be given the product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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