Product image of Paracetamol Capsules 500mg (Paracetamol) supplied by GNH India

Paracetamol Capsules 500mg

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol Capsules 500mg (Paracetamol)

Paracetamol, the active ingredient in Paracetamol Capsules 500mg, is an Analgesic presented as a 500mg capsule for oral use. It treats mild to moderate pain and fever in adults and children.
GNH India supplies Paracetamol Capsules 500mg as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Noumed Life Sciences

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Indications & Clinical Uses

Paracetamol is an analgesic and antipyretic that acts on the prostaglandin pathway to relieve pain and reduce fever.

  • Headache: alleviates pain associated with tension or migraine.
  • Fever: lowers elevated body temperature.
  • Musculoskeletal pain: reduces discomfort from strains, sprains or arthritis.
  • Dental pain: provides relief after procedures or toothache.
  • Cold/flu symptoms: eases fever and general aches.

How It Works

  • Paracetamol works by inhibiting the cyclooxygenase (COX) enzymes, primarily COX‑2, in the central nervous system. This reduces the synthesis of prostaglandins that mediate pain and fever, leading to analgesic and antipyretic effects without significant peripheral anti‑inflammatory activity.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild stomach upset.
  • Rash: skin irritation or mild erythema.
  • Headache: occasional worsening of headache.
  • Dizziness: transient light‑headedness.
  • Gastrointestinal discomfort: mild abdominal pain.
  • Elevated liver enzymes: transient increase in lab values.

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome: severe skin reaction.
  • Hepatotoxicity: liver injury, especially with overdose.
  • Anaphylaxis: rare severe allergic response.
  • Blood dyscrasias: agranulocytosis or thrombocytopenia.
  • Severe skin reactions: toxic epidermal necrolysis.
  • Renal impairment: rare kidney function decline.

Precautions & Warnings

Paracetamol should be used with caution and according to professional guidance.

  • Liver function monitoring: assess hepatic health before prolonged use.
  • Alcohol avoidance: limit intake to reduce liver risk.
  • Lowest effective dose: use the smallest dose that provides relief.
  • Daily limit adherence: do not exceed 4 g per day for adults.
  • Pregnancy caution: consult a healthcare provider before use.
  • Store below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Paracetamol can interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Warfarin: increased anticoagulant effect, risk of bleeding.
  • Carbamazepine: reduced analgesic efficacy.
  • Rifampicin: decreased plasma concentration.
  • Phenytoin: lowered therapeutic effect.

Moderate Interactions (Monitor Closely)

  • Alcohol: heightened risk of hepatotoxicity.
  • HIV protease inhibitors: possible increase in paracetamol levels.
  • Oral contraceptives: may reduce contraceptive effectiveness.

Frequently Asked Questions

Paracetamol Capsules 500mg are used to relieve mild to moderate pain such as headaches, dental pain, musculoskeletal discomfort, and to reduce fever associated with infections or inflammatory conditions. The medication works systemically after oral ingestion.

Paracetamol acts by inhibiting cyclooxygenase enzymes in the central nervous system, which reduces the production of prostaglandins responsible for pain signaling and fever generation. This mechanism provides analgesic and antipyretic effects without strong peripheral anti‑inflammatory activity.

The appropriate dose is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and other medications. Typical adult dosing ranges from one to two capsules every 4‑6 hours, not exceeding 4 g per day.

Paracetamol is generally considered safe for short‑term use during pregnancy and lactation when prescribed by a healthcare provider. However, pregnant or nursing individuals should consult their doctor before starting the medication to ensure appropriate dosing and monitoring.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Paracetamol provides analgesic and antipyretic effects without significant anti‑inflammatory activity, whereas ibuprofen is a non‑steroidal anti‑inflammatory drug (NSAID) that also reduces inflammation. Paracetamol is often preferred when NSAIDs are contraindicated, such as in patients with gastric ulcer risk or certain cardiovascular conditions.

Store the capsules at temperatures below 25 °C in their original packaging, protecting them from moisture and direct sunlight. Keep the container tightly closed and out of reach of children.

The capsules are taken orally with a glass of water. They may be taken with or without food, but taking them with food can reduce occasional stomach discomfort. Swallow the capsule whole; do not crush or chew.

The most serious risks include severe liver injury (hepatotoxicity) especially with overdose or chronic high‑dose use, and rare allergic reactions such as Stevens‑Johnson syndrome or anaphylaxis. Prompt medical attention is required if signs of liver dysfunction or severe skin reactions appear.

Individuals with known hypersensitivity to paracetamol, severe liver disease, or those who have exceeded the recommended daily dose should avoid using the product. Patients taking certain anticoagulants, carbamazepine, or other interacting drugs should consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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