Product image of Paracetamol Cf (Paracetamol) supplied by GNH India

Paracetamol Cf

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol Cf (Paracetamol)

Paracetamol, the active ingredient in Paracetamol Cf, is an Analgesic presented as an oral tablet for oral use. It reduces pain and fever and is commonly used in adults and children for mild to moderate discomfort and is available over the counter in many regions.

GNH India supplies Paracetamol Cf as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. Our distribution network ensures consistent quality, regulatory compliance, and reliable delivery across EU and global markets.

Manufacturer / TM Owner

Centrafarm B.V.

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Indications & Clinical Uses

Paracetamol is an analgesic and antipyretic used to treat pain and fever.

  • Headache: provides relief of mild to moderate headache pain.
  • Fever: reduces elevated body temperature.
  • Musculoskeletal pain: alleviates aches associated with strains and sprains.
  • Dental pain: eases discomfort after dental procedures.
  • Cold symptoms: helps relieve sore throat and body aches.

How It Works

  • Paracetamol acts centrally by inhibiting cyclooxygenase enzymes, particularly COX‑3, within the brain and spinal cord, which reduces the synthesis of prostaglandins that mediate pain and fever. Its peripheral anti‑inflammatory activity is minimal, distinguishing it from NSAIDs, and its effect on the hypothalamic heat‑regulation center contributes to its antipyretic action.

Side Effects

Paracetamol may cause adverse reactions, ranging from mild to serious.

Common Side Effects

  • Nausea
  • Rash or mild skin irritation
  • Elevated liver enzymes (transient)
  • Headache
  • Dizziness

Serious or Rare Side Effects

  • Severe liver injury or hepatic failure
  • Anaphylaxis (severe allergic reaction)
  • Blood disorders such as thrombocytopenia
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Acute kidney injury (rare)
  • Severe skin reactions (e.g., erythema multiforme)

Precautions & Warnings

Use of Paracetamol requires attention to several safety considerations.

  • Dose adjustment in hepatic impairment: reduce dose and monitor liver function.
  • Avoid in known hypersensitivity to paracetamol: discontinue use.
  • Caution with chronic alcohol use: increased risk of hepatotoxicity.
  • Do not exceed recommended daily maximum: avoid overdose.
  • Use in pregnancy only if clearly needed: consult healthcare professional.
  • Store at ambient temperature: keep in original packaging, protect from moisture and heat.

Avoid Interactions

Paracetamol can interact with other medicines, necessitating careful management.

Major Interactions (Avoid)

  • Concurrent use with strong CYP450 inducers (e.g., rifampicin): may reduce efficacy.
  • Combination with other hepatotoxic drugs (e.g., high‑dose ibuprofen): increased liver risk.
  • Co‑administration with warfarin: may enhance anticoagulant effect.

Moderate Interactions (Monitor Closely)

  • Alcohol consumption: may increase hepatotoxicity.
  • Use with enzyme‑inducing anticonvulsants: may alter metabolism.
  • Concurrent use with other antipyretics: risk of dosing error.

Frequently Asked Questions

Paracetamol Cf is used to relieve mild to moderate pain such as headaches, musculoskeletal aches, dental discomfort, and to reduce fever associated with common colds or other febrile conditions. It is an over‑the‑counter analgesic and antipyretic suitable for adults and children when dosed appropriately.

Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, especially COX‑3, which lowers the production of prostaglandins that signal pain and fever. This central action reduces the perception of pain and helps reset the hypothalamic temperature set‑point, thereby lowering fever.

The exact dose of Paracetamol Cf is determined by the prescribing healthcare professional based on the patient’s age, weight, and clinical condition. Standard adult dosing typically does not exceed 4 g per day, but the prescriber will set the appropriate regimen for each individual.

Paracetamol is generally considered safe for short‑term use during pregnancy and lactation when used at the lowest effective dose. However, it should only be taken if clearly needed and under the guidance of a healthcare provider, as individual circumstances may vary.

To order Paracetamol Cf, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Paracetamol differs from non‑steroidal anti‑inflammatory drugs (NSAIDs) by having minimal peripheral anti‑inflammatory activity and a lower risk of gastrointestinal irritation. It is often preferred when NSAIDs are contraindicated, but it lacks the anti‑inflammatory strength of agents like ibuprofen or naproxen.

Paracetamol Cf should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the container tightly closed and out of reach of children.

Paracetamol Cf is administered orally, typically as a tablet that is swallowed whole with water. It can be taken with or without food, and the dosage schedule is determined by the prescribing clinician.

The most serious risk is hepatotoxicity, especially when the maximum daily dose is exceeded or combined with other liver‑affecting substances such as alcohol. Rare severe reactions include anaphylaxis, Stevens‑Johnson syndrome, and blood disorders, which require immediate medical attention.

Paracetamol Cf should be avoided by individuals with known hypersensitivity to paracetamol, severe liver disease, or those who regularly consume excessive alcohol. It should also be used with caution in patients taking other hepatotoxic medications or anticoagulants, and only under medical advice.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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