Product image of Paracetamol Clonmel (Paracetamol) supplied by GNH India

Paracetamol Clonmel

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol Clonmel (Paracetamol)

Paracetamol, the active ingredient in Paracetamol Clonmel, is an analgesic and antipyretic presented as an oral dosage form for oral use. It treats mild to moderate pain and reduces fever in adults and children, and is widely used worldwide.

GNH India supplies Paracetamol Clonmel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality compliance with EU standards and reliable global distribution.

Manufacturer / TM Owner

Clonmel Healthcare Ltd.

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Indications & Clinical Uses

Paracetamol acts as a systemic analgesic and antipyretic, relieving discomfort associated with various painful and febrile conditions.

  • Fever: reduces elevated body temperature, providing relief from febrile discomfort.
  • Headache: alleviates tension or migraine‑type headache pain.
  • Musculoskeletal pain: eases aches in muscles, joints and back.
  • Toothache: diminishes dental pain following injury or infection.
  • Cold and flu symptoms: helps control mild pain and fever that accompany viral upper‑respiratory infections.
  • Post‑operative pain: provides mild to moderate pain relief after minor surgical procedures.

How It Works

  • Paracetamol exerts its effect primarily by inhibiting cyclooxygenase (COX) enzymes in the central nervous system, which reduces the synthesis of prostaglandins involved in pain signalling and thermoregulation. The peripheral COX inhibition is weak, allowing antipyretic and analgesic actions without significant anti‑inflammatory activity. This central action leads to decreased neuronal excitability and a lower hypothalamic set‑point for temperature.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild stomach upset.
  • Abdominal discomfort: occasional stomach pain.
  • Rash: skin redness or itching.
  • Elevated liver enzymes: transient increase detectable in blood tests.

Serious or Rare Side Effects

  • Severe allergic reaction: anaphylaxis or angioedema.
  • Hepatotoxicity: liver injury, especially with overdose.
  • Blood disorders: thrombocytopenia or neutropenia.

Precautions & Warnings

When using Paracetamol, certain precautions help ensure safe and effective therapy.

  • Dose limitation: do not exceed the maximum daily amount recommended for the age group.
  • Alcohol use: avoid excessive alcohol consumption while taking the medication.
  • Liver disease: use with caution in patients with existing liver impairment.
  • Children: follow pediatric dosing guidelines and keep out of reach of children.
  • Drug interactions: review concomitant medications for potential interactions.
  • Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Paracetamol may interact with several medicines, influencing its efficacy or safety.

Major Interactions (Avoid)

  • Alcohol: combined use increases risk of liver injury.
  • Warfarin: may potentiate anticoagulant effect, raising bleeding risk.
  • Carbamazepine: induces metabolism, reducing paracetamol effectiveness.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: may slightly reduce efficacy.
  • Antifungal agents (e.g., fluconazole): can alter paracetamol metabolism.

Frequently Asked Questions

Paracetamol Clonmel is used to relieve mild to moderate pain such as headache, toothache, muscle aches, and to reduce fever associated with common colds, flu and other febrile illnesses. It provides symptomatic relief for adults and children when a non‑opioid analgesic is appropriate.

Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which lowers the production of prostaglandins that mediate pain and regulate body temperature. This central inhibition reduces the perception of pain and resets the hypothalamic temperature set‑point, producing antipyretic effects.

The exact dose of Paracetamol Clonmel is determined by a qualified prescriber based on the patient’s age, weight, clinical condition and local guidelines. Healthcare professionals typically follow standard dosing ranges for paracetamol, but the final regimen should always be confirmed by the prescribing clinician.

Paracetamol is generally considered the analgesic/antipyretic of choice during pregnancy and lactation when used at recommended doses, but safety cannot be guaranteed for every individual. Pregnant or nursing women should consult their healthcare provider before using Paracetamol Clonmel to ensure it is appropriate for their situation.

To order Paracetamol Clonmel, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

The most common alternative to paracetamol is ibuprofen, a non‑steroidal anti‑inflammatory drug (NSAID). While both relieve pain and fever, ibuprofen also has anti‑inflammatory properties and may cause gastrointestinal irritation or affect kidney function. Paracetamol lacks significant anti‑inflammatory activity but is generally gentler on the stomach and is preferred when NSAIDs are contraindicated.

Paracetamol Clonmel should be stored at temperatures below 25 °C, in its original packaging, protected from moisture, direct sunlight and excessive heat. Keep the product out of reach of children and do not use it after the expiry date printed on the label.

Paracetamol Clonmel is administered orally. It may be supplied as tablets, capsules or a liquid suspension, and should be taken with water or as directed by the prescriber. The medication is intended for systemic absorption through the gastrointestinal tract.

The most serious risks include severe allergic reactions such as anaphylaxis, and hepatotoxicity, especially when the maximum daily dose is exceeded or combined with alcohol. Rare blood disorders like thrombocytopenia or neutropenia have also been reported. Patients should seek immediate medical attention if they experience signs of a serious reaction.

Paracetamol Clonmel should be avoided by individuals with known hypersensitivity to paracetamol or any excipients in the formulation, those with severe liver impairment, and patients who have experienced a serious reaction to the drug previously. It is also contraindicated in children under the age for which the product is not formulated.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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