Product image of Paracetamol/Codeine Accord (Paracetamol, Codeine Phosphate Hemihydrate) supplied by GNH India

Paracetamol/Codeine Accord

Active Ingredient:
Paracetamol, Codeine Phosphate Hemihydrate
Origin:
EU

Paracetamol/Codeine Accord (Paracetamol, Codeine Phosphate Hemihydrate)

International sale not permitted. Listed for the domestic market and B2B only.

Paracetamol, the active ingredient in Paracetamol/Codeine Accord, is a combination analgesic presented as a tablet for oral use. It treats mild to moderate pain and reduces fever in adult patients. GNH India supplies Paracetamol/Codeine Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

GNH India supplies Paracetamol/Codeine Accord as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Accord Healthcare B.V.

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Indications & Clinical Uses

Paracetamol/Codeine Accord is a combination analgesic that provides relief across several pain‑related pathways.

  • Acute musculoskeletal pain: helps alleviate pain associated with strains, sprains and minor injuries.
  • Post‑operative pain: supports pain control after minor surgical procedures.
  • Dental pain: reduces discomfort following dental extractions or procedures.
  • Headache and migraine relief: assists in managing moderate headache episodes.
  • Fever reduction: lowers elevated body temperature in adults.

How It Works

  • Paracetamol acts primarily by inhibiting central cyclooxygenase enzymes, reducing prostaglandin synthesis in the brain, which lowers pain perception and temperature set‑point. Codeine phosphate hemihydrate is an opioid agonist that binds to µ‑opioid receptors in the central nervous system, enhancing analgesic effects through modulation of pain signalling pathways.

Side Effects

Paracetamol/Codeine Accord may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nausea
  • Dizziness
  • Constipation
  • Drowsiness
  • Dry mouth
  • Sweating

Serious or Rare Side Effects

  • Respiratory depression
  • Severe allergic reaction (anaphylaxis)
  • Hepatotoxicity in overdose
  • Opioid dependence or withdrawal syndrome
  • Low blood pressure (hypotension)
  • Seizures (rare)

Precautions & Warnings

When using Paracetamol/Codeine Accord, several safety considerations should be observed.

  • Liver function monitoring: assess hepatic health before prolonged use.
  • Avoid alcohol: concurrent intake increases risk of liver injury.
  • Opioid tolerance assessment: evaluate patient history for opioid dependence.
  • Pregnancy and lactation: use only if clearly needed and prescribed.
  • Concomitant CNS depressants: monitor for additive sedation.
  • Store below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Paracetamol/Codeine Accord can interact with a variety of medicines, requiring careful management.

Major Interactions (Avoid)

  • Other opioid analgesics: risk of additive respiratory depression.
  • Benzodiazepines or barbiturates: heightened central nervous system depression.
  • Mono‑Mono‑Mono  

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Frequently Asked Questions

  

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

International sale not permitted. Listed for the domestic market and B2B only.

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