Product image of Paracetamol Codeine Frilab (Paracetamol, Codeine Phosphate Hemihydrate) supplied by GNH India

Paracetamol Codeine Frilab

Active Ingredient:
Paracetamol, Codeine Phosphate Hemihydrate
Origin:
EU

Paracetamol Codeine Frilab (Paracetamol, Codeine Phosphate Hemihydrate)

Paracetamol, the active ingredient in Paracetamol Codeine Frilab, is an analgesic presented as an oral dosage form for oral use. It is combined with codeine phosphate hemihydrate to provide relief of mild to moderate pain and reduce fever in adults.

GNH India supplies Paracetamol Codeine Frilab as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and procurement teams worldwide.

Manufacturer / TM Owner

Laboratoires Frilab

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Paracetamol Codeine Frilab is used in the management of pain and fever through central analgesic and antipyretic pathways.

  • Mild to moderate pain: alleviates headache, musculoskeletal and dental discomfort.
  • Post‑operative pain: reduces pain after minor surgical procedures.
  • Fever: lowers elevated body temperature associated with infection or inflammation.

How It Works

  • Paracetamol acts centrally by inhibiting cyclooxygenase enzymes, decreasing prostaglandin synthesis and producing analgesic and antipyretic effects. Codeine phosphate hemihydrate is a weak µ‑opioid receptor agonist that enhances analgesia and can suppress cough by acting on the brainstem respiratory centre.

Side Effects

Paracetamol Codeine Frilab may cause a range of adverse reactions, most of which are dose‑related and reversible.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Drowsiness: feeling of sleepiness or reduced alertness.
  • Constipation: difficulty passing stools.
  • Dizziness: light‑headed sensation.
  • Dry mouth: reduced salivation.
  • Sweating: increased perspiration.

Serious or Rare Side Effects

  • Respiratory depression: slowed breathing, especially at high doses.
  • Hepatotoxicity: liver injury from excessive paracetamol exposure.
  • Allergic reaction: rash, itching, or swelling.
  • Seizures: rare occurrence in susceptible individuals.
  • Severe hypotension: marked drop in blood pressure.
  • Dependence or misuse: potential for opioid‑related dependence.

Precautions & Warnings

Paracetamol Codeine Frilab should be used with caution in specific clinical situations.

  • Liver disease: avoid or limit use due to paracetamol metabolism.
  • Renal impairment: monitor kidney function when using codeine.
  • Alcohol consumption: increase risk of hepatotoxicity and sedation.
  • Elderly patients: lower doses may be required to reduce side‑effect risk.
  • Concomitant CNS depressants: may enhance drowsiness and respiratory depression.
  • Store at ambient temperature: keep below 25 °C, in the original container, protected from moisture and direct sunlight.

Avoid Interactions

Paracetamol Codeine Frilab can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Other opioids: additive respiratory depression.
  • Benzodiazepines or barbiturates: heightened CNS depression.
  • Monoamine oxidase inhibitors (MAOIs): risk of serotonin syndrome.

Moderate Interactions (Monitor Closely)

  • CYP2D6 inhibitors (e.g., fluoxetine, quinidine): may reduce codeine conversion to morphine.
  • Anticoagulants (e.g., warfarin): paracetamol may increase bleeding risk.
  • Antihistamines: may enhance drowsiness.
  • Diuretics: possible reduction in renal clearance of codeine.

Frequently Asked Questions

Paracetamol Codeine Frilab is indicated for the relief of mild to moderate pain such as headache, musculoskeletal or dental pain, and for the reduction of fever. It combines paracetamol’s antipyretic action with codeine’s opioid‑mediated analgesia to provide effective symptom control.

Paracetamol acts centrally by inhibiting cyclooxygenase enzymes, which reduces the synthesis of prostaglandins involved in pain signaling and temperature regulation. This results in analgesic and antipyretic effects without significant peripheral anti‑inflammatory activity.

The specific dose and dosing interval are determined by the prescribing clinician based on the patient’s age, weight, clinical condition and any concomitant medications. Healthcare professionals should follow local prescribing guidelines and adjust the regimen as needed.

Safety in pregnancy and lactation has not been fully established. Paracetamol is generally considered low‑risk, but codeine crosses the placenta and may affect the newborn. Use only if the potential benefit outweighs the risk and after consulting a qualified healthcare provider.

Enquiries can be submitted via the product page on gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Plain paracetamol provides analgesic and antipyretic effects but lacks the opioid component. Adding codeine enhances pain relief, especially for moderate pain, but also introduces opioid‑related risks such as sedation, respiratory depression and potential dependence. Choice depends on pain severity and patient risk factors.

Store the product at ambient temperature, preferably below 25 °C. Keep it in the original packaging, protect it from moisture, direct sunlight and extreme heat to maintain potency and stability throughout its shelf life.

The medication is taken orally, usually with a glass of water. It may be taken with or without food, but taking it with food can reduce gastrointestinal upset. Patients should follow the dosing instructions provided by their prescriber.

Serious risks include respiratory depression, especially in opioid‑naïve individuals or when combined with other CNS depressants, hepatotoxicity from excessive paracetamol, severe allergic reactions, and the potential for dependence or misuse of the codeine component.

Patients with known hypersensitivity to paracetamol, codeine or any excipients, those with severe liver or respiratory disease, individuals taking monoamine oxidase inhibitors, and children under the age limits set by local regulations should avoid this product unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Paracetamol, Codeine Phosphate Hemihydrate

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT