Product image of Paracetamol Crescent Pharma (Paracetamol) supplied by GNH India

Paracetamol Crescent Pharma

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol Crescent Pharma (Paracetamol)

Paracetamol, the active ingredient in Paracetamol Crescent Pharma, is an analgesic, antipyretic presented as a tablet for oral use. It treats mild to moderate pain and reduces fever in adults and children, and it is a core component of many over‑the‑counter pain‑relief products and essential‑medicine lists across the European Union.

GNH India supplies Paracetamol Crescent Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with distribution channels that meet EU regulatory standards and ensure product integrity from manufacture to end‑user.

Manufacturer / TM Owner

Crescent Pharma Limited

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Indications & Clinical Uses

Paracetamol is an analgesic and antipyretic that acts on the prostaglandin pathway to relieve pain and fever.

  • Headache: provides relief of tension‑type and mild migraine headaches.
  • Fever: reduces elevated body temperature associated with infections.
  • Musculoskeletal pain: alleviates mild to moderate pain from sprains, strains or backache.
  • Dental pain: helps manage postoperative dental discomfort and toothache.

How It Works

  • Paracetamol exerts its effect primarily by inhibiting cyclooxygenase (COX) enzymes in the central nervous system, especially COX‑2, leading to reduced synthesis of prostaglandins that mediate pain and fever. Its peripheral anti‑inflammatory activity is minimal, which distinguishes it from non‑steroidal anti‑inflammatory drugs.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild stomach upset after ingestion.
  • Abdominal discomfort: occasional stomach pain or dyspepsia.
  • Rash: skin redness or mild itching.
  • Sweating: increased perspiration without exertion.
  • Headache: paradoxical headache in some users.

Serious or Rare Side Effects

  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hepatotoxicity: liver injury, especially with overdose or chronic high use.
  • Blood disorders: agranulocytosis or thrombocytopenia.
  • Anaphylaxis: rare severe allergic reaction.
  • Renal impairment: acute kidney injury in susceptible individuals.

Precautions & Warnings

Paracetamol should be used with attention to patient‑specific factors and proper handling.

  • Assess liver function: avoid use in patients with severe hepatic impairment.
  • Limit alcohol consumption: concurrent alcohol increases risk of liver injury.
  • Do not exceed recommended daily dose: maximum 4 g per day for adults.
  • Use with caution in renal impairment: dose adjustment may be required.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Paracetamol can interact with several medicines, requiring awareness of the interaction level.

Major Interactions (Avoid)

  • Warfarin: may increase anticoagulant effect and bleeding risk.
  • Other hepatotoxic drugs (e.g., isoniazid, methotrexate): combined use raises potential for liver injury.
  • Alcohol: concurrent intake heightens risk of hepatic toxicity.

Moderate Interactions (Monitor Closely)

  • Carbamazepine: may reduce analgesic effectiveness of paracetamol.
  • Phenytoin: can increase metabolism of paracetamol, lowering plasma levels.
  • Other antipyretics (e.g., ibuprofen): concurrent use may increase risk of overdose.

Frequently Asked Questions

Paracetamol Crescent Pharma is used to relieve mild to moderate pain such as headache, musculoskeletal discomfort, and dental pain, and to reduce fever associated with common infections. It is an over‑the‑counter analgesic and antipyretic that works in both adults and children when administered according to professional guidance.

Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which reduces the production of prostaglandins that signal pain and raise body temperature. This central action provides analgesic and antipyretic effects while having minimal anti‑inflammatory activity compared with non‑steroidal anti‑inflammatory drugs.

The appropriate dose of Paracetamol Crescent Pharma is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and any existing medical considerations. Patients should follow the prescriber’s instructions and never exceed the recommended maximum daily amount.

Paracetamol is generally considered compatible with pregnancy and breastfeeding when used at the lowest effective dose for the shortest duration. However, pregnant or nursing individuals should consult their healthcare provider before starting any medication to ensure it is appropriate for their specific situation.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the team provides pricing, availability, shipping details (including any cold‑chain requirements) and assists with import documentation.

Compared with non‑steroidal anti‑inflammatory drugs (NSAIDs) such as ibuprofen, paracetamol provides effective pain relief and fever reduction with a lower risk of gastrointestinal irritation and platelet inhibition. However, it lacks significant anti‑inflammatory activity, so NSAIDs may be preferred when inflammation is a primary concern.

Paracetamol Crescent Pharma should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments.

Paracetamol Crescent Pharma is supplied as oral tablets that are taken by mouth with water. The tablets may be swallowed whole or, if appropriate for the patient, chewed or dissolved according to the prescriber’s instructions. It is not intended for injection or topical use.

The most serious risks include severe liver injury, especially when the maximum daily dose is exceeded or when combined with alcohol or other hepatotoxic agents, and rare but life‑threatening skin reactions such as Stevens‑Johnson syndrome. Prompt medical attention is required if signs of liver dysfunction or severe skin rash develop.

Paracetamol Crescent Pharma should be avoided in individuals with known hypersensitivity to paracetamol or any excipients in the tablet, in patients with severe hepatic impairment, and in those who have experienced serious skin reactions to paracetamol previously. Pregnant or breastfeeding women should seek medical advice before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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