Product image of Paracetamol Doz (Paracetamol) supplied by GNH India

Paracetamol Doz

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol Doz (Paracetamol)

Paracetamol, the active ingredient in Paracetamol Doz, is an analgesic presented as an oral dosage form for oral use. It provides pain relief and reduces fever in adults and children when appropriate dosing is applied. The medication is classified as an over‑the‑counter product and is commonly employed in the management of mild to moderate pain and temperature elevation.

GNH India supplies Paracetamol Doz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to European Union quality standards and provides reliable global distribution.

Manufacturer / TM Owner

Doz S.A.

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Indications & Clinical Uses

Paracetamol is used to alleviate symptoms in several common pain and fever pathways.

  • Pain relief: reduces mild to moderate nociceptive pain such as headache, toothache, or muscle aches.
  • Fever reduction: lowers elevated body temperature by acting on the hypothalamic heat‑regulation center.
  • Headache: alleviates tension‑type and mild migraine‑associated headaches.
  • Dental pain: provides analgesia for discomfort after dental procedures.
  • Musculoskeletal pain: eases aches and soreness caused by strain or over‑use.

How It Works

  • Paracetamol exerts its therapeutic effect primarily by inhibiting cyclooxygenase (COX) enzymes in the central nervous system, which leads to decreased synthesis of prostaglandins involved in pain signaling and thermoregulation. The reduction of prostaglandin levels in the hypothalamus lowers the set‑point for body temperature, while peripheral analgesic action results from central modulation of nociceptive pathways.

Side Effects

Paracetamol may be associated with a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nausea: occasional upset stomach or feeling of queasiness.
  • Abdominal discomfort: mild stomach pain or indigestion.
  • Rash or mild skin irritation: transient erythema or itching.
  • Dizziness: brief episodes of light‑headedness.

Serious or Rare Side Effects

  • Severe liver injury: potential hepatotoxicity, especially with overdose or chronic high‑dose use.
  • Allergic reactions: including anaphylaxis, angioedema, or severe skin eruptions.
  • Blood disorders: rare cases of thrombocytopenia or neutropenia.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis: life‑threatening skin reactions.

Precautions & Warnings

When using Paracetamol Doz, consider the following safety measures.

  • Assess liver function: avoid use in patients with severe hepatic impairment.
  • Limit alcohol consumption: concurrent intake may increase risk of liver toxicity.
  • Use the lowest effective dose: follow prescriber guidance to minimize adverse effects.
  • Monitor during pregnancy: consult a healthcare professional before use.
  • Avoid in children without appropriate pediatric dosing: adhere to age‑specific recommendations.
  • Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Paracetamol Doz can interact with several medicines; awareness of these interactions helps ensure safe use.

Major Interactions (Avoid)

  • Warfarin: may increase anticoagulant effect and bleeding risk.
  • Alcohol: combined use heightens potential for hepatotoxicity.
  • Carbamazepine: may accelerate paracetamol metabolism, reducing efficacy.

Moderate Interactions (Monitor Closely)

  • Isoniazid: concurrent use can raise risk of liver injury.
  • Phenytoin: may increase paracetamol clearance, requiring dose adjustment.
  • Certain antiretrovirals (e.g., ritonavir): can affect hepatic metabolism and necessitate monitoring.

Frequently Asked Questions

Paracetamol Doz is an over‑the‑counter oral product that provides relief from mild to moderate pain such as headaches, toothaches, and muscle aches, and it helps lower fever by acting on the body's temperature‑regulation center. It is commonly used in both adult and pediatric populations when appropriate dosing is applied.

Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which reduces the production of prostaglandins that mediate pain and fever. This central inhibition lowers the hypothalamic set‑point for temperature and diminishes the perception of nociceptive signals, resulting in analgesic and antipyretic effects.

The specific dose of Paracetamol Doz is determined by the prescribing healthcare professional based on the patient’s age, weight, and clinical condition. Typical adult regimens range from 500 mg to 1000 mg every 4‑6 hours, not exceeding the maximum daily limit, but exact dosing should always follow the prescriber’s instructions.

Paracetamol is generally considered compatible with pregnancy and lactation when used at recommended doses, but safety data are limited. Women who are pregnant or breastfeeding should consult their healthcare provider before starting Paracetamol Doz to ensure it is appropriate for their specific situation.

To place an order, submit an enquiry on the Paracetamol Doz product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

The primary alternative to paracetamol is non‑steroidal anti‑inflammatory drugs (NSAIDs) such as ibuprofen. Unlike NSAIDs, paracetamol has minimal anti‑inflammatory activity and does not irritate the gastric lining, making it a preferred option for patients at risk of gastrointestinal bleeding. However, NSAIDs may provide stronger anti‑inflammatory effects when needed.

Paracetamol Doz should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and avoid storing it in humid environments such as bathrooms.

Paracetamol Doz is taken orally, usually with a glass of water. It can be taken with or without food, but if gastrointestinal discomfort occurs, it may be helpful to ingest it with a small amount of food. The exact administration schedule should follow the prescriber’s guidance.

The most serious risks include severe liver injury, especially with overdose or chronic high‑dose use, and rare allergic reactions such as anaphylaxis or severe skin conditions like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they notice signs of liver dysfunction or a severe rash.

Paracetamol Doz should be avoided in individuals with known hypersensitivity to paracetamol, those with severe hepatic impairment, and patients who have experienced serious adverse reactions to the drug. Caution is also advised for children under the recommended age or weight limits, and for patients taking interacting medications without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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