Product image of Paracetamol Hasco (Paracetamol) supplied by GNH India

Paracetamol Hasco

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol Hasco (Paracetamol)

Paracetamol, the active ingredient in Paracetamol Hasco, is an analgesic presented as a rectal formulation for rectal use. It reduces mild to moderate pain and lowers fever in adults, adolescents, and children, providing symptomatic relief for conditions such as headache, musculoskeletal discomfort, and febrile illnesses.

GNH India supplies Paracetamol Hasco as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and regulatory requirements to ensure product safety and efficacy across global markets.

Manufacturer / TM Owner

Hasco-Lek

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Indications & Clinical Uses

Paracetamol is an analgesic and antipyretic used to manage pain and fever.

  • Pain: Provides relief of mild to moderate nociceptive pain.
  • Fever: Reduces elevated body temperature associated with infectious or inflammatory processes.
  • Headache: Alleviates tension‑type and mild migraine headaches.
  • Musculoskeletal discomfort: Eases aches from strains, sprains, or over‑exertion.
  • Dental pain: Controls pain following dental procedures or toothache.

How It Works

  • Paracetamol acts centrally by inhibiting the cyclooxygenase (COX) enzymes, primarily COX‑2, within the brain and spinal cord. This inhibition reduces the synthesis of prostaglandins, which are mediators of pain and fever, thereby providing analgesic and antipyretic effects without significant peripheral anti‑inflammatory activity.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: Mild gastrointestinal upset.
  • Abdominal discomfort: Stomach pain or discomfort.
  • Rash: Skin redness or mild itching.
  • Sweating: Increased perspiration.
  • Dizziness: Light‑headed sensation.
  • Headache: Persistent mild headache.

Serious or Rare Side Effects

  • Hepatotoxicity: Severe liver injury, especially with overdose.
  • Stevens‑Johnson syndrome: Rare severe skin reaction.
  • Anaphylaxis: Immediate hypersensitivity reaction.
  • Blood dyscrasias: Uncommon blood cell abnormalities.
  • Renal impairment: Kidney function reduction in susceptible individuals.
  • Severe skin reactions: Toxic epidermal necrolysis.

Precautions & Warnings

Paracetamol should be used with caution in certain populations and conditions.

  • Assess liver function: Avoid or limit use in patients with severe hepatic disease.
  • Monitor renal function: Use carefully in individuals with impaired kidney function.
  • Limit alcohol intake: Reduce risk of liver toxicity when combined with alcohol.
  • Pregnancy and lactation: Use only if clearly needed and after professional advice.
  • Pediatric dosing: Ensure appropriate formulation and dosing for children.
  • Store at ambient temperature: Keep below 25 °C, protect from moisture and direct sunlight.

Avoid Interactions

Paracetamol may interact with other medicines, altering its efficacy or safety.

Major Interactions (Avoid)

  • Alcohol: Increases risk of hepatotoxicity.
  • Warfarin: May enhance anticoagulant effect, raising bleeding risk.
  • Carbamazepine: Induces metabolism, reducing analgesic effect.

Moderate Interactions (Monitor Closely)

  • Isoniazid: May increase risk of liver injury.
  • Phenytoin: Can affect drug metabolism.
  • Oral contraceptives: May slightly reduce contraceptive effectiveness.
  • Rifampicin: May lower plasma concentrations of paracetamol.

Frequently Asked Questions

Paracetamol Hasco contains paracetamol, an analgesic and antipyretic indicated for the relief of mild to moderate pain such as headache, musculoskeletal aches, dental pain, and for the reduction of fever associated with various illnesses.

Paracetamol works by inhibiting central cyclooxygenase enzymes, mainly COX‑2, which reduces the production of prostaglandins in the brain and spinal cord. This action lowers the perception of pain and helps reset the body’s temperature set‑point, thereby reducing fever.

The appropriate dose of Paracetamol Hasco is determined by a qualified health‑care professional based on the patient’s age, weight, clinical condition, and local prescribing guidelines. The prescriber will specify the exact amount and frequency.

Paracetamol is generally considered the analgesic/antipyretic of choice when treatment is required during pregnancy or lactation, but it should only be used after professional medical advice. The prescriber will weigh potential benefits against any possible risks.

To request Paracetamol Hasco, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Paracetamol Hasco offers analgesic and antipyretic effects without the anti‑inflammatory activity of NSAIDs, making it suitable for patients who need pain relief but must avoid gastric irritation or platelet inhibition. Compared with opioids, it has a lower risk of dependence and respiratory depression.

Paracetamol Hasco should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and direct sunlight. This helps maintain product stability and potency throughout its shelf life.

Paracetamol Hasco is supplied as a rectal formulation intended for rectal administration. The appropriate dosage form is inserted into the rectum, where it dissolves and is absorbed systemically to provide analgesic and antipyretic effects.

The most serious risk is hepatotoxicity, especially with overdose or when combined with alcohol or other hepatotoxic agents. Rare but severe reactions can include Stevens‑Johnson syndrome, toxic epidermal necrolysis, anaphylaxis, and significant blood or renal abnormalities.

Paracetamol Hasco should be avoided in individuals with known hypersensitivity to paracetamol, severe liver disease, or those who are taking other medications that may cause dangerous liver injury. Pregnant or lactating women should only use it under medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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