Product image of Paracetamol/Ibuprofen Inn-Farm (Ibuprofen, Paracetamol) supplied by GNH India

Paracetamol/Ibuprofen Inn-Farm

Active Ingredient:
Ibuprofen, Paracetamol
Origin:
EU

Paracetamol/Ibuprofen Inn-Farm (Ibuprofen, Paracetamol)

Ibuprofen, the active ingredient in Paracetamol/Ibuprofen Inn-Farm, is a non‑opioid analgesic and nonsteroidal anti‑inflammatory drug (NSAID) presented as a combination oral tablet for systemic use. It treats mild to moderate pain and fever in adults and children when used according to medical guidance.

GNH India supplies Paracetamol/Ibuprofen Inn-Farm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Inn-Farm D.O.O.

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Indications & Clinical Uses

Paracetamol/Ibuprofen combines two analgesic pathways to provide relief for several common painful or febrile conditions.

  • Headache: reduces pain intensity and associated discomfort.
  • Musculoskeletal pain: alleviates inflammation‑related aches such as back or joint pain.
  • Fever: lowers elevated body temperature in acute infections.
  • Dental pain: eases post‑extraction or procedural discomfort.
  • Menstrual cramps: diminishes cramp‑related pelvic pain.

How It Works

  • Paracetamol acts centrally to inhibit cyclooxygenase enzymes, reducing prostaglandin synthesis in the brain, while ibuprofen blocks peripheral cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, decreasing prostaglandin production at sites of inflammation. The combined effect provides analgesia, antipyresis, and anti‑inflammatory activity.

Side Effects

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects

  • Nausea: mild stomach upset that may resolve with food.
  • Dyspepsia: occasional heartburn or indigestion.
  • Headache: transient headache unrelated to the condition being treated.
  • Dizziness: brief episodes of light‑headedness.
  • Rash: mild skin redness or itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: black or tarry stools, vomiting blood.
  • Hepatic injury: jaundice, dark urine, elevated liver enzymes.
  • Renal impairment: reduced urine output, swelling of limbs.
  • Severe allergic reaction: swelling of face or throat, difficulty breathing.
  • Stevens‑Johnson syndrome: painful skin blistering and detachment.

Precautions & Warnings

Before initiating therapy, consider the following safety measures:

  • Assess liver function: avoid use in patients with severe hepatic impairment.
  • Evaluate kidney health: caution in chronic renal disease.
  • Review cardiovascular risk: ibuprofen may increase blood pressure.
  • Avoid concurrent NSAIDs: reduces risk of gastrointestinal toxicity.
  • Monitor for allergy: discontinue if rash or swelling develops.
  • Store at ambient temperature: keep below 25°C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Paracetamol/Ibuprofen may interact with several drug classes, requiring attention to dosage and monitoring.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • High‑dose corticosteroids: heightened gastrointestinal ulcer risk.
  • Selective serotonin reuptake inhibitors (SSRIs): additive bleeding potential.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in antihypertensive effect.
  • Diuretics: may diminish renal clearance of ibuprofen.
  • Lithium: ibuprofen can raise serum lithium levels.

Frequently Asked Questions

Paracetamol/Ibuprofen Inn-Farm is a fixed‑dose combination of paracetamol and ibuprofen used to relieve mild to moderate pain and to reduce fever. It is commonly prescribed for headaches, musculoskeletal aches, dental pain, menstrual cramps and febrile illnesses when a single‑agent therapy is insufficient.

Paracetamol works mainly in the central nervous system to inhibit cyclooxygenase enzymes and lower prostaglandin production, providing antipyretic and analgesic effects. Ibuprofen blocks peripheral cyclooxygenase‑1 and‑2 enzymes, reducing prostaglandin synthesis at sites of inflammation, which adds anti‑inflammatory and additional analgesic benefits. Together they offer complementary pain relief.

The specific dose and dosing interval are determined by the prescribing clinician based on the patient’s age, weight, clinical condition and any concomitant therapies. Healthcare professionals should follow local prescribing guidelines and adjust the regimen to achieve optimal pain or fever control while minimizing risk.

Paracetamol is generally considered safe in pregnancy when used at recommended doses, while ibuprofen is usually avoided, especially in the third trimester, due to potential fetal cardiovascular effects. Breastfeeding mothers should consult a healthcare provider, as ibuprofen passes into milk in small amounts. Professional guidance is essential before use.

To place an order, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

The fixed‑dose combination provides synergistic analgesic and antipyretic effects, often achieving faster pain relief and better fever control than either agent alone. It may reduce the need for higher individual doses, potentially lowering the risk of dose‑related side effects while covering both central and peripheral pain pathways.

Store the tablets at ambient temperature, preferably below 25 °C, in the original packaging to protect from moisture and direct sunlight. Keep the product out of reach of children and do not use it after the expiry date printed on the label.

Paracetamol/Ibuprofen Inn-Farm is supplied as oral tablets that should be swallowed whole with water. It is intended for systemic use, and the tablet should be taken with or without food as directed by the prescribing clinician.

Serious risks include gastrointestinal bleeding, severe liver injury, acute kidney injury, and rare hypersensitivity reactions such as Stevens‑Johnson syndrome or anaphylaxis. Patients should seek immediate medical attention if they notice black stools, jaundice, swelling, difficulty breathing, or extensive skin rash.

Individuals with known hypersensitivity to paracetamol, ibuprofen or any other NSAID, those with active peptic ulcer disease, severe liver or kidney impairment, uncontrolled hypertension, or who are in the third trimester of pregnancy should avoid this product unless specifically advised by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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