Product image of Paracetamol/Ibuprofen Jed (Ibuprofen, Paracetamol) supplied by GNH India

Paracetamol/Ibuprofen Jed

Active Ingredient:
Ibuprofen, Paracetamol
Origin:
EU

Paracetamol/Ibuprofen Jed (Ibuprofen, Paracetamol)

Ibuprofen, the active ingredient in Paracetamol/Ibuprofen Jed, is an analgesic/anti-inflammatory presented as a combination tablet for oral use. It treats pain and fever in adults and children when used according to medical guidance.

GNH India supplies Paracetamol/Ibuprofen Jed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Jed Pharma Ltd

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Indications & Clinical Uses

Paracetamol/Ibuprofen Jed combines two well‑known analgesics that act on inflammatory and pain pathways.

  • Headache: provides relief of mild to moderate headache symptoms.
  • Fever: reduces elevated body temperature in febrile illnesses.
  • Musculoskeletal pain: alleviates pain associated with strains, sprains and minor joint discomfort.

How It Works

  • The product combines ibuprofen, a non‑steroidal anti‑inflammatory drug that inhibits cyclo‑oxygenase (COX‑1 and COX‑2) enzymes, reducing prostaglandin synthesis, with paracetamol, which acts centrally to inhibit a variant of the cyclooxygenase pathway and modulates pain signalling pathways, resulting in combined analgesic and antipyretic effects.

Side Effects

Paracetamol/Ibuprofen Jed may cause a range of adverse reactions, most of which are dose‑dependent and reversible.

Common Side Effects

  • Nausea: mild stomach upset may occur.
  • Dyspepsia: occasional indigestion or heartburn.
  • Headache: paradoxical headache in some users.
  • Dizziness: transient light‑headedness.
  • Rash: mild skin irritation.
  • Elevated liver enzymes: mild, transient rise in blood tests.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: ulceration or bleeding in the stomach or intestines.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hepatotoxicity: significant liver injury, especially with overdose.
  • Renal impairment: reduced kidney function or acute kidney injury.
  • Anaphylaxis: severe allergic reaction with airway compromise.
  • Cardiovascular events: increased risk of heart attack or stroke in susceptible individuals.

Precautions & Warnings

When considering Paracetamol/Ibuprofen Jed, several safety measures should be observed.

  • Assess renal function: evaluate kidney health before initiating therapy.
  • Monitor hepatic status: check liver enzymes in patients with existing liver disease.
  • Avoid in ulcer history: patients with active gastrointestinal ulcers should not use.
  • Limit alcohol intake: concurrent alcohol use may increase risk of liver injury.
  • Use lowest effective dose: aim for the minimal dose needed for symptom control.
  • Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Paracetamol/Ibuprofen Jed can interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants: may increase bleeding risk when combined with warfarin or direct oral anticoagulants.
  • High‑dose aspirin: additive gastrointestinal toxicity.
  • Lithium: ibuprofen can reduce renal clearance of lithium, raising serum levels.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: may diminish antihypertensive effect and affect renal function.
  • Diuretics: concurrent use can increase risk of renal impairment.
  • Selective serotonin reuptake inhibitors (SSRIs): may modestly raise bleeding risk.

Frequently Asked Questions

Paracetamol/Ibuprofen Jed is a combination oral tablet that provides pain relief and reduces fever. It is commonly used for mild to moderate headache, fever associated with infections, and musculoskeletal discomfort such as strains or sprains, when prescribed by a healthcare professional.

Ibuprofen belongs to the non‑steroidal anti‑inflammatory drug class and blocks cyclo‑oxygenase‑1 and cyclo‑oxygenase‑2 enzymes, decreasing the production of prostaggletons that cause inflammation, pain and fever. This action complements the central analgesic effect of paracetamol.

The appropriate dose is determined by the prescribing clinician based on the patient’s age, weight, medical condition and other medications. The prescriber will specify the exact strength and frequency that should be followed.

Use of this combination during pregnancy or lactation should only occur under medical supervision. Ibuprofen is generally avoided in the third trimester, and paracetamol is preferred; a healthcare provider will assess the risk‑benefit balance for each individual.

To place an order, submit an enquiry on the product page at gnhindia.com indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

The combination offers additive analgesic and antipyretic effects, often achieving pain relief at lower individual doses of each component compared with monotherapy. This may reduce the risk of dose‑related side effects, but the safety profile reflects the combined potential for gastrointestinal, renal and hepatic effects.

Store the tablets at or below 25 °C in a dry place, protected from moisture and direct sunlight. Keep them in the original container with the lid tightly closed to maintain stability and potency.

The product is taken orally, usually with a full glass of water. It may be taken with or without food, although taking it with food can help minimise gastrointestinal discomfort.

Serious risks include gastrointestinal bleeding, severe skin reactions such as Stevens‑Johnson syndrome, liver injury, kidney impairment and increased cardiovascular events. Patients should seek immediate medical attention if they notice signs of bleeding, rash, jaundice or sudden swelling.

Individuals with a known allergy to ibuprofen, paracetamol or any excipients, active gastrointestinal ulcers, severe liver or kidney disease, and those in the third trimester of pregnancy should avoid this medication unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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