Product image of Paracetamol/Ibuprofen Vale (Ibuprofen, Paracetamol) supplied by GNH India

Paracetamol/Ibuprofen Vale

Active Ingredient:
Ibuprofen, Paracetamol
Origin:
EU

Paracetamol/Ibuprofen Vale (Ibuprofen, Paracetamol)

Ibuprofen, the active ingredient in Paracetamol/Ibuprofen Vale, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a intravenous formulation for systemic use. It is combined with paracetamol to provide pain relief and fever reduction in adult patients.

GNH India supplies Paracetamol/Ibuprofen Vale as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Vale Pharmaceuticals Limited

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Indications & Clinical Uses

Paracetamol/Ibuprofen Vale combines two analgesic agents that act on inflammatory and temperature‑regulation pathways.

  • Mild to moderate pain: reduces pain intensity in conditions such as headache, dental pain, musculoskeletal discomfort, and postoperative pain.
  • Fever: lowers elevated body temperature associated with infections or inflammatory disorders.
  • Inflammation: diminishes inflammatory response in conditions like rheumatoid arthritis flares and soft‑tissue injuries.

How It Works

  • Ibuprofen inhibits cyclo‑oxygenase (COX‑1 and COX‑2) enzymes, decreasing prostaglandin synthesis that mediates inflammation, pain and fever. Paracetamol’s exact mechanism is not fully understood but is thought to act centrally by inhibiting a variant of cyclo‑oxygenase and modulating serotonergic pathways, providing antipyretic and analgesic effects.

Side Effects

Paracetamol/Ibuprofen Vale may elicit a range of adverse reactions.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain.
  • Headache.
  • Dizziness.
  • Mild elevation of ALT or AST.
  • Injection site irritation.

Serious or Rare Side Effects

  • Severe gastrointestinal bleeding or ulceration.
  • Acute kidney injury.
  • Anaphylactic or severe hypersensitivity reactions.
  • Hepatotoxicity, especially with high‑dose paracetamol exposure.
  • Stevens‑Stevens Stevens "."

Precautions & Warnings

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Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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