Product image of Paracetamol/Ibuprofeno Nutra Essential (Ibuprofen, Paracetamol) supplied by GNH India

Paracetamol/Ibuprofeno Nutra Essential

Active Ingredient:
Ibuprofen, Paracetamol
Origin:
EU

Paracetamol/Ibuprofeno Nutra Essential (Ibuprofen, Paracetamol)

Ibuprofen, the active ingredient in Paracetamol/Ibuprofeno Nutra Essential, is a nonsteroidal anti-inflammatory drug (NSAID) and analgesic presented as a combined formulation for oral use. It treats mild to moderate pain and reduces fever in adults and children when appropriate.

GNH India supplies Paracetamol/Ibuprofeno Nutra Essential as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Nutra Essential Otc, S.L.

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Indications & Clinical Uses

Paracetamol/Ibuprofeno Nutra Essential combines ibuprofen and paracetamol to provide analgesic and antipyretic effects across several common conditions.

  • Headache: reduces pain intensity and associated discomfort.
  • Dental pain: alleviates postoperative or inflammatory dental discomfort.
  • Musculoskeletal pain: eases aches from strains, sprains and minor arthritis.
  • Fever: lowers elevated body temperature in acute febrile states.
  • Menstrual cramps: diminishes cramp‑related pelvic pain.

How It Works

  • Ibuprofen inhibits cyclo‑oxygenase (COX‑1 and COX‑2) enzymes, decreasing prostaglandin synthesis that mediates inflammation, pain and fever. Paracetamol acts centrally by inhibiting a variant of the COX enzyme and modulating serotonergic pathways, providing additional analgesic and antipyretic effects without significant peripheral anti‑inflammatory activity.

Side Effects

Paracetamol/Ibuprofeno Nutra Essential may cause a range of adverse reactions, most of which are dose‑dependent and reversible.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or mild abdominal pain.
  • Headache: transient worsening of head pain.
  • Dizziness: light‑headed feeling or unsteadiness.
  • Skin rash: mild erythema or itching.
  • Elevated liver enzymes: mild, asymptomatic increase in laboratory values.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: black or tarry stools, vomiting blood.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hepatotoxicity: jaundice, marked elevation of liver enzymes, hepatic failure.
  • Renal impairment: reduced urine output, swelling, increased serum creatinine.
  • Anaphylaxis: rapid onset of breathing difficulty, swelling of face or throat, hypotension.

Precautions & Warnings

When using Paracetamol/Ibuprofeno Nutra Essential, consider the following safety measures:

  • Assess renal function: evaluate baseline kidney health before initiating therapy.
  • Monitor hepatic status: avoid use in patients with active liver disease or elevated enzymes.
  • Limit duration: do not exceed recommended treatment length without medical review.
  • Avoid concurrent NSAIDs: concurrent use with other NSAIDs increases risk of gastrointestinal injury.
  • Pregnancy and lactation: use only under medical supervision, weighing potential benefits against risks.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Paracetamol/Ibuprofeno Nutra Essential can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • High‑dose aspirin aspirin: heightened gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): amplified bleeding risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: possible reduction in renal perfusion.
  • Diuretics (loop or thiazide): heightened risk of renal function decline.
  • Lithium: ibuprofen may raise serum lithium levels.
  • Methotrexate: reduced clearance leading to toxicity.
  • Alcohol: additive hepatotoxic potential.

Frequently Asked Questions

Paracetamol/Ibuprofeno Nutra Essential is a combined ibuprofen and paracetamol product that provides analgesic and antipyretic effects. It is commonly used to relieve mild to moderate pain such as headache, dental pain, musculoskeletal aches, menstrual cramps, and to lower fever in acute febrile episodes.

Ibuprofen blocks cyclo‑oxygenase‑1 and cycloxy‑oxygenase‑2 enzymes, reducing the production of prostaglandins that cause inflammation, pain and fever. This inhibition lessens peripheral inflammation and sensitisation of nerve endings, contributing to the overall pain‑relieving effect of the combination.

The specific dose and dosing interval are determined by the prescribing clinician based on the patient’s age, weight, clinical condition and any concomitant therapies. Healthcare professionals should follow local prescribing guidelines and adjust the regimen as needed for safety and efficacy.