Product image of Paracetamol/Ibuprofeno Sandoz Care (Ibuprofen, Paracetamol) supplied by GNH India

Paracetamol/Ibuprofeno Sandoz Care

Active Ingredient:
Ibuprofen, Paracetamol
Origin:
EU

Paracetamol/Ibuprofeno Sandoz Care (Ibuprofen, Paracetamol)

Ibuprofen and Paracetamol, the active ingredients in Paracetamol/Ibuprofeno Sandoz Care, are a non‑steroidal anti‑inflammatory drug and an analgesic/antipyretic presented as an oral tablet for oral use. The combination targets pain and fever, providing relief for mild to moderate symptoms in adults and children when appropriate.

GNH India supplies Paracetamol/Ibuprofeno Sandoz Care as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product complies with EU quality standards and is manufactured under strict GMP conditions. It is available for bulk distribution to meet global demand.

Manufacturer / TM Owner

Sandoz Farmacéutica, S.A.

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Indications & Clinical Uses

  • Paracetamol/Ibuprofeno Sandoz Care combines an NSAID and an antipyretic to address pain and fever across common clinical situations.
  • Mild to moderate pain: reduces pain intensity in conditions such as headache, dental or musculoskeletal pain.
  • Fever: lowers elevated body temperature associated with infections or inflammatory processes.
  • Post‑operative discomfort: provides analgesia after minor surgical procedures.

How It Works

  • Ibuprofen inhibits cyclooxygenase (COX‑1 and COX‑2) enzymes, decreasing peripheral prostaglandin synthesis and reducing inflammation and pain. Paracetamol acts centrally, likely inhibiting a variant of COX in the brain and modulating serotonergic pathways, which lowers fever and provides analgesic effects without significant peripheral anti‑inflammatory activity.

Side Effects

Common Side Effects

  • Nausea
  • Dizziness
  • Headache
  • Mild gastrointestinal discomfort

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis)
  • Liver injury (hepatotoxicity)
  • Gastrointestinal bleeding or ulceration
  • Kidney function impairment

Precautions & Warnings

Before use, consider the following precautions:

  • Assess liver function: avoid in patients with severe hepatic impairment.
  • Assess renal function: use cautiously in renal disease.
  • Avoid in known hypersensitivity to ibuprofen or paracetamol.
  • Limit use in elderly: higher risk of gastrointestinal adverse events.
  • Avoid concomitant use with other NSAIDs or acetaminophen‑containing products.
  • Store at ambient temperature: keep in original packaging, protect from moisture.

Avoid Interactions

Paracetamol/Ibuprofeno Sandoz Care may interact with other medicines as follows.

Major Interactions (Avoid)

  • Concurrent use with anticoagulants (e.g., warfarin): increased bleeding risk.
  • Combination with other NSAIDs or corticosteroids: heightened gastrointestinal toxicity.
  • Use with lithium: ibuprofen may increase lithium levels.
  • Co‑administration with methotrexate: ibuprofen may raise methotrexate toxicity.
  • Concurrent use with alcohol: increased liver toxicity risk.

Moderate Interactions (Monitor Closely)

  • Interaction with antihypertensives (e.g., ACE inhibitors): may reduce renal perfusion.
  • Use with diuretics: risk of renal impairment.

Frequently Asked Questions

Paracetamol/Ibuprofeno Sandoz Care is used to relieve mild to moderate pain such as headache, dental or musculoskeletal discomfort, and to reduce fever associated with infections or inflammatory conditions. The combination of ibuprofen and paracetamol provides both anti‑inflammatory and antipyretic effects, making it suitable for a range of common symptomatic indications.

Ibuprofen belongs to the non‑steroidal anti‑inflammatory drug (NSAID) class. It blocks cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are required for the synthesis of prostaglandins that mediate inflammation, pain, and fever. By lowering prostaglandin levels at the site of injury, ibuprofen reduces swelling, alleviates pain, and contributes to fever reduction.

The appropriate dose is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and any relevant medical history. Patients should follow the prescriber’s instructions and the product label; no specific dosing regimen is provided here.

Safety in pregnancy and lactation has not been definitively established for the combination. Healthcare providers should evaluate the risk‑benefit profile for each individual, and patients are advised to consult their physician before using the product while pregnant or breastfeeding.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets. After submission, the sales team will verify trade or institutional credentials, then respond with pricing, availability, shipping details (including any cold‑chain requirements if applicable) and the necessary import documentation.

When ibuprofen or paracetamol is used alone, each provides pain relief or fever reduction through a single mechanism. The combined formulation offers additive analgesic and antipyretic effects, potentially achieving faster or more complete symptom control while allowing lower individual doses of each component. However, the combination also carries the combined safety profile of both agents, which must be considered in clinical decision‑making.

Paracetamol/Ibuprofeno Sandoz Care should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture and direct sunlight, and ensure the packaging remains tightly closed until use.

The product is taken orally, usually with a full glass of water. It may be taken with or without food, although taking it with food can reduce the likelihood of gastrointestinal discomfort. Patients should swallow the tablet whole and not crush or chew it unless specifically instructed by a healthcare professional.

Serious adverse reactions include severe allergic responses such as anaphylaxis, liver injury (hepatotoxicity), gastrointestinal bleeding or ulceration, and impaired kidney function. Patients should seek immediate medical attention if they experience symptoms such as rash, swelling, jaundice, dark urine, persistent abdominal pain, or signs of bleeding.

Individuals with known hypersensitivity to ibuprofen, paracetamol, or any excipients in the formulation should avoid the product. It is also contraindicated in patients with severe liver or kidney disease, active gastrointestinal ulceration, or those taking anticoagulants where bleeding risk is high, unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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