Product image of Paracetamol Leidapharm (Paracetamol) supplied by GNH India

Paracetamol Leidapharm

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol Leidapharm (Paracetamol)

Paracetamol, the active ingredient in Paracetamol Leidapharm, is a non‑opioid analgesic and antipyretic presented as a tablet for oral use. It is commonly used to relieve mild to moderate pain and reduce fever in adults and children.

GNH India supplies Paracetamol Leidapharm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Leidapharm B.V.

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Indications & Clinical Uses

Paracetamol Leidapharm is an analgesic and antipyretic that acts on common pain‑related pathways and fever mechanisms.

  • Headache: provides relief from tension‑type and mild migraine headaches.
  • Fever: reduces elevated body temperature associated with viral or bacterial infections.
  • Musculoskeletal pain: eases discomfort from strains, sprains and minor joint aches.
  • Dental pain: alleviates pain following dental procedures or toothache.
  • Menstrual cramps: helps lessen cramping pain during menstruation.

How It Works

  • Paracetamol exerts its effect by inhibiting cyclo‑oxygenase enzymes in the central nervous system, particularly COX‑2, which lowers prostaglandin synthesis. This action reduces the perception of pain and resets the hypothalamic set‑point for temperature regulation, providing analgesic and antipyretic effects without significant peripheral anti‑inflammatory activity.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild stomach upset may be reported.
  • Rash: occasional skin redness or mild itching.
  • Elevated liver enzymes: transient increase detected in blood tests.

Serious or Rare Side Effects

  • Hepatotoxicity: risk of liver injury with overdose or chronic high‑dose use.
  • Stevens‑Johnson syndrome: rare severe skin reaction.
  • Blood disorders: uncommon cases of thrombocytopenia or neutropenia.
  • Anaphylaxis: very rare allergic reaction requiring immediate medical attention.

Precautions & Warnings

Paracetamol should be used with awareness of specific safety considerations.

  • Dose limits: adhere to maximum daily intake to avoid liver toxicity.
  • Alcohol use: limit consumption as it may increase liver risk.
  • Pre‑existing liver disease: use only under medical supervision.
  • Pregnancy and breastfeeding: consult healthcare professional before use.
  • Children: ensure age‑appropriate formulation and dosing.
  • Store below 25°C: keep in the original packaging, protect from moisture.

Avoid Interactions

Paracetamol may interact with several medicines, requiring monitoring.

Major Interactions (Avoid)

  • Warfarin: may enhance anticoagulant effect and increase bleeding risk.
  • Isoniazid: can raise risk of liver toxicity when combined.

Moderate Interactions (Monitor Closely)

  • Antiepileptic drugs (e.g., carbamazepine, phenytoin): may reduce paracetamol plasma levels.
  • Rifampicin: may increase metabolism of paracetamol, lowering efficacy.
  • Oral contraceptives: may slightly increase hepatotoxic potential.
  • High‑dose vitamin C: may affect renal clearance of paracetamil.

Frequently Asked Questions

Paracetamol Leidapharm is used to relieve mild to moderate pain such as headache, dental pain, musculoskeletal aches and to lower fever. It is an oral non‑opioid analgesic and antipyretic that provides symptomatic relief in a wide range of common conditions.

Paracetamol works by inhibiting central cyclo‑oxygenase enzymes, especially COX‑2, which reduces prostaglandin production in the brain. This decreases pain signalling and lowers the hypothalamic set‑point for body temperature, producing analgesic and antipyretic effects without strong peripheral anti‑inflammatory action.

The appropriate dose of Paracetamol Leidapharm is determined by a prescriber based on the patient’s age, weight, clinical condition and local guidelines. Healthcare professionals set the exact amount and frequency to ensure safe and effective use.

Paracetamol is generally considered low risk in pregnancy and breastfeeding when used at recommended doses, but a healthcare professional should evaluate each case. Women should discuss any use with their obstetrician or physician to confirm safety for mother and infant.

To order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and import documentation.

Compared with non‑steroidal anti‑inflammatory drugs (NSAIDs), paracetamol provides pain relief and fever reduction without significant anti‑inflammatory effects or gastrointestinal irritation. It is often preferred when NSAIDs are contraindicated, but it lacks the anti‑inflammatory potency of drugs like ibuprofen.

Paracetamol Leidapharm should be stored below 25 °C in its original packaging, protected from moisture and direct sunlight. Maintaining these conditions helps preserve tablet integrity and potency throughout its shelf life.

Paracetamol Leidapharm is taken orally, usually as a tablet swallowed with water. It can be taken with or without food, and the exact administration schedule is defined by the prescribing clinician.

The most serious risk is hepatotoxicity, which can occur with overdose or chronic high‑dose use, potentially leading to liver failure. Rare severe reactions such as Stevens‑Johnson syndrome or anaphylaxis also require immediate medical attention.

Individuals with known hypersensitivity to paracetamol or its excipients, severe liver impairment, or those taking interacting medications like high‑dose warfarin without monitoring should avoid using this product unless directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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