Product image of Paracetamol Mabo (Paracetamol) supplied by GNH India

Paracetamol Mabo

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol Mabo (Paracetamol)

Paracetamol, the active ingredient in Paracetamol Mabo, is an analgesic presented as an oral tablet for oral use. It provides relief from mild to moderate pain and reduces fever in adults and children when appropriate. It is widely used in primary care and over‑the‑counter settings for temporary symptom management.

GNH India supplies Paracetamol Mabo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across all markets. The company adheres to stringent quality standards and provides reliable logistics support for global distribution.

Manufacturer / TM Owner

Mabo-Farma, S.A

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Indications & Clinical Uses

Paracetamol is an analgesic/antipyretic that acts on the prostaglandin pathway to relieve pain and reduce fever.

  • Headache: alleviates mild to moderate headache pain.
  • Fever: lowers elevated body temperature in adults and children.
  • Musculoskeletal pain: reduces discomfort from strains, sprains, and backache.
  • Dental pain: eases pain associated with toothache and dental procedures.

How It Works

  • Paracetamol exerts its effect primarily by inhibiting the cyclooxygenase (COX) enzymes in the central nervous system, especially COX‑2, leading to decreased synthesis of prostaglandins that mediate pain and fever. Its peripheral anti‑inflammatory activity is minimal, which accounts for the lack of significant anti‑inflammatory effects compared with NSAIDs. The reduced prostaglandin levels lower the hypothalamic set‑point for temperature regulation and diminish nociceptive signaling in the spinal cord.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild stomach upset that may occur after ingestion.
  • Rash: occasional skin irritation or mild allergic reaction.
  • Headache: paradoxical headache in a small number of users.
  • Dizziness: transient light‑headedness reported by some patients.
  • Elevated liver enzymes: mild, usually reversible increase in hepatic enzymes.

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome: severe skin reaction requiring immediate medical attention.
  • Toxic hepatitis: potentially life‑threatening liver injury.
  • Agranulocytosis: rare reduction in white blood cells.
  • Anaphylaxis: acute allergic reaction with breathing difficulty.
  • Severe skin reactions: such as toxic epidermal necrolysis.
  • Blood disorders: rare cases of thrombocytopenia or hemolytic anemia.

Precautions & Warnings

Paracetamol should be used with caution in specific populations and clinical situations.

  • Dosage adjustment: reduce dose in patients with hepatic impairment.
  • Alcohol use: avoid excessive alcohol consumption while taking the product.
  • Pregnancy: use only if clearly needed and after medical advice.
  • Age: caution in children under two years unless prescribed.
  • Concomitant hepatotoxic drugs: monitor liver function when combined with other hepatotoxic agents.
  • Store below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Paracetamol may interact with several medicines; some interactions require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Warfarin: may increase anticoagulant effect, monitor INR closely.
  • Isoniazid: risk of hepatotoxicity increases.
  • Carbamazepine: may reduce paracetamol clearance, leading to toxicity.

Moderate Interactions (Monitor Closely)

  • Alcohol: combined use can heighten liver injury risk.
  • Other hepatotoxic drugs: such as certain antituberculars, monitor liver enzymes.
  • Enzyme inducers: e.g., rifampicin may lower paracetamol plasma levels.

Frequently Asked Questions

Paracetamol Mabo is used to relieve mild to moderate pain such as headache, dental pain, musculoskeletal discomfort, and to reduce fever. It is commonly employed in primary care and over‑the‑counter settings for temporary symptom management in both adults and children when appropriate.

Paracetamol works by inhibiting central cyclooxygenase enzymes, primarily COX‑2, which reduces the synthesis of prostaglandins involved in pain signaling and temperature regulation. This action lowers the hypothalamic set‑point for body temperature and diminishes nociceptive transmission, providing analgesic and antipyretic effects.

The appropriate dose of Paracetamol Mabo is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and any existing liver or renal impairment. The prescriber will set the exact regimen, and patients should follow that guidance precisely.

Paracetamol is generally considered the analgesic/antipyretic of choice during pregnancy and lactation when needed, but it should only be used after consulting a healthcare provider. The prescriber will weigh the benefits against any potential risks to the mother and infant before recommending use.

To order Paracetamol Mabo, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials. The team then replies with pricing, availability, shipping details and any required import documentation.

The primary alternative to paracetamol is non‑steroidal anti‑inflammatory drugs (NSAIDs) such as ibuprofen. Unlike NSAIDs, paracetamol has minimal peripheral anti‑inflammatory activity and a lower risk of gastrointestinal irritation, but it lacks the anti‑inflammatory strength of NSAIDs. Both classes are effective for pain and fever, but choice depends on patient tolerance and comorbidities.

Paracetamol Mabo should be stored below 25 °C in a dry environment. Keep the tablets in the original packaging to protect them from moisture and light. Do not store in a bathroom or near a heat source, and keep out of reach of children.

Paracetamol Mabo is supplied as oral tablets intended for swallowing with a full glass of water. It is taken by mouth according to the prescriber’s instructions, typically with or without food. The tablets should not be crushed or chewed unless specifically advised by a healthcare professional.

The most serious risks include severe liver injury (toxic hepatitis) and rare hypersensitivity reactions such as Stevens‑Johnson syndrome or anaphylaxis. These events are uncommon but require immediate medical attention if symptoms such as jaundice, rash, or difficulty breathing develop.

Paracetamol Mabo should be avoided in individuals with known hypersensitivity to paracetamol or any tablet excipients, in patients with severe hepatic impairment, and in those who have experienced serious adverse reactions such as Stevens‑Johnson syndrome. Caution is also advised for patients with chronic alcohol use or concurrent hepatotoxic medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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