Product image of Paracetamol Noridem (Paracetamol) supplied by GNH India

Paracetamol Noridem

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol Noridem (Paracetamol)

Paracetamol, the active ingredient in Paracetamol Noridem, is an analgesic presented as a 500 mg tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children.

GNH India supplies Paracetamol Noridem as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Noridem Enterprises Ltd

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Indications & Clinical Uses

Paracetamol Noridem is an analgesic and antipyretic that acts on common pain‑related pathways and fever mechanisms.

  • Headache: provides relief from tension‑type and mild migraine pain.
  • Fever: lowers elevated body temperature in infectious or inflammatory states.
  • Musculoskeletal pain: eases aches associated with back strain, sprains and minor joint discomfort.
  • Dental pain: reduces pain following dental procedures or toothache.
  • Post‑operative discomfort: helps manage mild pain after minor surgical interventions.

How It Works

  • Paracetamol exerts its effect primarily by inhibiting cyclooxygenase enzymes in the central nervous system, which reduces prostaglandin synthesis. This action lowers the pain‑sensing threshold and modulates the hypothalamic heat‑regulation centre, producing analgesic and antipyretic effects without significant peripheral anti‑inflammatory activity.

Side Effects

Paracetamol Noridem is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild stomach upset reported by some users.
  • Skin rash: occasional mild erythema or itching.
  • Elevated liver enzymes: transient increase detected in routine tests.

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome: severe skin reaction requiring immediate medical attention.
  • Hepatotoxicity: risk of liver injury, especially with overdose or chronic high‑dose use.
  • Anaphylaxis: rare allergic reaction with symptoms such as swelling, difficulty breathing, or hives.

Precautions & Warnings

When using Paracetamol Noridem, consider the following safety measures:

  • Dose limitation: do not exceed the maximum daily amount recommended by a healthcare professional.
  • Liver health: avoid use in patients with severe hepatic impairment or active liver disease.
  • Alcohol consumption: limit alcohol intake as it may increase risk of liver toxicity.
  • Concomitant medications: review all other drugs for additional paracetamol content to prevent accidental overdose.
  • Pregnancy and lactation: use only if clearly indicated and prescribed by a clinician.
  • Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Paracetamol Noridem may interact with several medicines; monitoring is advised.

Major Interactions (Avoid)

  • Warfarin: may enhance anticoagulant effect and increase bleeding risk.
  • Isoniazid: can potentiate hepatotoxic potential when combined.

Moderate Interactions (Monitor Closely)

  • Antiepileptics (e.g., carbamazepine, phenytoin): may increase hepatic metabolism of paracetamol.
  • HIV protease inhibitors: can alter paracetamol clearance.
  • High‑dose vitamin C: may affect renal excretion of paracetamol metabolites.

Frequently Asked Questions

Paracetamol Noridem is used to relieve mild to moderate pain such as headache, dental or musculoskeletal discomfort, and to lower fever. It is an oral analgesic and antipyretic commonly prescribed for short‑term symptom control in adults and children when indicated by a healthcare professional.

Paracetamol works by inhibiting central cyclooxygenase enzymes, which reduces the production of prostaglandins involved in pain signalling and temperature regulation. This central action lowers the pain threshold and resets the hypothalamic set‑point for body temperature, providing analgesic and antipyretic effects without strong peripheral anti‑inflammatory activity.

The appropriate dose of Paracetamol Noridem is determined by the prescribing clinician based on the patient’s age, weight, clinical condition and any existing health concerns. Patients should follow the prescriber’s instructions and never exceed the recommended maximum daily amount.

Paracetamol is generally considered safe for short‑term use during pregnancy and lactation when prescribed by a healthcare professional. However, it should only be used if clearly indicated, and the prescriber will weigh potential benefits against any risks, especially in the first trimester or when high doses are contemplated.

To order Paracetamol Noridem, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Paracetamol Noridem provides analgesic and antipyretic effects similar to other paracetamol products but differs from non‑steroidal anti‑inflammatory drugs (NSAIDs) by lacking significant peripheral anti‑inflammatory activity and having a lower risk of gastrointestinal irritation. It is often chosen when NSAIDs are contraindicated or when a milder pain‑relief option is sufficient.

Paracetamol Noridem tablets should be stored at temperatures below 25 °C, in their original packaging, protected from moisture and direct sunlight. Keep the container tightly closed and out of reach of children to maintain product stability and potency.

Paracetamol Noridem is taken orally, usually with a glass of water. The tablet should be swallowed whole and not crushed or chewed unless specifically advised by a healthcare professional. Administration is typically timed according to the prescriber’s dosing schedule.

The most serious risks include hepatotoxicity, which can occur with overdose or chronic high‑dose use, and rare severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis. Prompt medical attention is required if signs of liver injury or severe skin rash develop.

Paracetamol Noridem should be avoided by individuals with known hypersensitivity to paracetamol, those with severe liver disease, and patients who are already taking other medications containing paracetamol that could lead to overdose. Clinicians should also assess risk before prescribing to patients with chronic alcohol use or certain metabolic disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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