Product image of Paracetamol Pharmaclan (Paracetamol) supplied by GNH India

Paracetamol Pharmaclan

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol Pharmaclan (Paracetamol)

Paracetamol, the active ingredient in Paracetamol Pharmaclan, is an analgesic and antipyretic presented as an oral tablet for oral use. It is used to relieve mild to moderate pain and to reduce fever in adults and children.
GNH India supplies Paracetamol Pharmaclan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Azinpharma Ltd.

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Indications & Clinical Uses

Paracetamol is an analgesic and antipyretic that works on the prostaglandin pathway to alleviate pain and fever.

  • Mild to moderate pain: provides relief for headache, toothache, musculoskeletal discomfort and menstrual cramps.
  • Fever: lowers elevated body temperature associated with infections or inflammatory conditions.
  • Cold and flu symptoms: eases aches, pains and fever that accompany upper respiratory infections.

How It Works

  • Paracetamol exerts its effect primarily by inhibiting cyclooxygenase (COX) enzymes in the central nervous system, which reduces the synthesis of prostaglandins involved in pain signaling and thermoregulation. Its action is largely peripheral at low doses, providing analgesia and antipyresis without significant anti‑inflammatory activity.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild stomach upset that may accompany dosing.
  • Abdominal discomfort: occasional stomach pain or indigestion.
  • Rash or mild skin irritation: transient erythema or itching.
  • Elevated liver enzymes: mild, reversible changes in laboratory tests.
  • Headache: occasional recurrence of headache after use.

Serious or Rare Side Effects

  • Hepatotoxicity: severe liver injury, especially with overdose or chronic high‑dose use.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis: rare severe skin reactions.
  • Blood dyscrasias: agranulocytosis or thrombocytopenia in very rare cases.
  • Anaphylaxis: acute allergic reaction with breathing difficulty and swelling.

Precautions & Warnings

Paracetamol should be used with attention to specific safety considerations.

  • Pregnancy: avoid use in the third trimester due to potential fetal harm.
  • Liver disease: use only under medical supervision, as impaired hepatic function increases toxicity risk.
  • Alcohol consumption: limit intake, as combined use raises the chance of liver injury.
  • Age: adjust dosing for children and the elderly; follow prescriber guidance.
  • Allergy: discontinue if hypersensitivity reactions such as rash or swelling occur.
  • Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Paracetamol can interact with several medicines, requiring attention to dosage and monitoring.

Major Interactions (Avoid)

  • Warfarin: may increase anticoagulant effect and bleeding risk.
  • Alcohol: concurrent use can potentiate hepatotoxicity.

Moderate Interactions (Monitor Closely)

  • Carbamazepine: may reduce paracetamol efficacy by increasing metabolism.
  • Isoniazid: combined use can heighten liver toxicity.
  • Phenobarbital: may increase paracetamol clearance, lowering therapeutic effect.

Frequently Asked Questions

Paracetamol Pharmaclan is used to relieve mild to moderate pain such as headaches, toothaches, muscle aches, and to reduce fever associated with infections or inflammatory conditions. It is commonly employed in both adult and pediatric populations under medical guidance.

Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which decreases the production of prostaglandins that signal pain and regulate body temperature. This results in analgesic and antipyretic effects without significant anti‑inflammatory activity.

The appropriate dose of Paracetamol Pharmaclan is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and local guidelines. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Paracetamol is generally considered safe for short‑term use during the first two trimesters of pregnancy and while breastfeeding when used at recommended doses. Use in the third trimester should be avoided unless specifically advised by a healthcare provider.

To order Paracetamol Pharmaclan, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Paracetamol Pharmaclan offers analgesic and antipyretic effects similar to other non‑opioid analgesics but lacks significant anti‑inflammatory activity found in NSAIDs. Compared with ibuprofen, it is gentler on the stomach and does not affect platelet function, making it suitable for patients who need pain relief without anti‑inflammatory action.

Paracetamol Pharmaclan should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and do not use if the packaging is damaged.

Paracetamol Pharmaclan is administered orally, typically as a tablet that is swallowed whole with water. The exact method of administration, including whether it should be taken with food, is determined by the prescribing clinician.

The most serious risks include severe liver injury (hepatotoxicity) especially with overdose or chronic high‑dose use, and rare severe skin reactions such as Stevens‑Johnson syndrome. Prompt medical attention is required if signs of liver dysfunction or severe skin rash appear.

Paracetamol Pharmaclan should be avoided by individuals with known hypersensitivity to paracetamol, those with severe liver impairment, and patients in the third trimester of pregnancy unless advised by a healthcare professional. Children under the recommended age or weight limits should not use adult formulations.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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