Product image of Paracetamol Ratiopharm (Paracetamol) supplied by GNH India

Paracetamol Ratiopharm

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol Ratiopharm (Paracetamol)

Paracetamol, the active ingredient in Paracetamol Ratiopharm, is an analgesic presented as a tablet for oral use. It is used to relieve mild to moderate pain and reduce fever in adults and children.
GNH India supplies Paracetamol Ratiopharm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ratiopharm Gmbh

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Indications & Clinical Uses

Paracetamol is an analgesic and antipyretic that acts on common pain and fever pathways.

  • Headache: provides relief from tension‑type and mild migraine pain.
  • Fever: reduces elevated body temperature associated with infections.
  • Musculoskeletal pain: eases aches from back strain, sprains, or osteoarthritis.
  • Dental pain: alleviates discomfort after dental procedures.
  • Menstrual cramps: lessens cramping and associated discomfort.

How It Works

  • Paracetamol exerts its effect primarily by inhibiting the cyclooxygenase (COX) enzymes in the central nervous system, especially COX‑2, which reduces the synthesis of prostaglandins involved in pain signalling and thermoregulation. The peripheral anti‑inflammatory activity is minimal, making it suitable for fever and mild pain relief without significant gastrointestinal effects.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild stomach upset after ingestion.
  • Skin rash: occasional mild erythema or itching.
  • Elevated liver enzymes: transient increase detected in blood tests.
  • Headache: paradoxical headache in a small subset of users.

Serious or Rare Side Effects

  • Hepatotoxicity: severe liver injury with overdose or chronic high dosing.
  • Stevens‑Johnson syndrome: rare severe skin reaction.
  • Anaphylaxis: extremely rare allergic reaction with breathing difficulty.
  • Blood dyscrasias: rare cases of thrombocytopenia or neutropenia.

Precautions & Warnings

Paracetamol should be used according to prescriber guidance and with awareness of specific safety considerations.

  • Liver disease: avoid or limit use in patients with hepatic impairment.
  • Alcohol consumption: limit intake as combined use increases liver toxicity risk.
  • Chronic kidney disease: monitor renal function when long‑term use is required.
  • Pregnancy: use only under medical advice, especially in the third trimester.
  • Children: ensure appropriate dose based on weight and age.

Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Paracetamol can interact with other medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Warfarin: may enhance anticoagulant effect, increasing bleeding risk.
  • Isoniazid: combined use can raise risk of liver injury.

Moderate Interactions (Monitor Closely)

  • Rifampicin: may increase metabolism of paracetamol, reducing its effectiveness.
  • Phenobarbital: can lower plasma levels of paracetamol.
  • Certain antiretrovirals (e.g., nevirapine): may increase hepatic stress when co‑administered.

Frequently Asked Questions

Paracetamol Ratiopharm is used to relieve mild to moderate pain such as headaches, dental discomfort, musculoskeletal aches, and to reduce fever associated with infections. It is an over‑the‑counter analgesic and antipyretic commonly prescribed for short‑term symptom management.

Paracetamol works by inhibiting central cyclooxygenase enzymes, especially COX‑2, which decreases the production of prostaglandins that mediate pain and fever. This central action reduces the perception of pain and helps lower elevated body temperature without significant peripheral anti‑inflammatory effects.

The appropriate dose of Paracetamol Ratiopharm is determined by the prescribing healthcare professional based on the patient’s age, weight, and clinical condition. Dosage instructions are provided on the product label and should be followed exactly as directed by the prescriber.

Paracetamol is generally considered safe for short‑term use during pregnancy and lactation when prescribed by a healthcare provider. However, it should be used only when clearly indicated, and the prescriber should evaluate the risk‑benefit profile for each individual case.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and necessary import documentation.

Paracetamol differs from non‑steroidal anti‑inflammatory drugs (NSAIDs) by having minimal peripheral anti‑inflammatory activity and a lower risk of gastrointestinal irritation. It is often preferred when NSAIDs are contraindicated, such as in patients with ulcer disease or certain cardiovascular risks.

Paracetamol Ratiopharm tablets should be stored at ambient temperature, below 25 °C, in the original packaging. Protect the product from moisture, heat, and direct sunlight to maintain its stability and potency throughout its shelf life.

Paracetamol Ratiopharm is administered orally. The tablets are swallowed whole with water. It is not intended for injection, topical use, or other routes of administration unless specifically formulated for such use.

The most serious risk is hepatotoxicity, which can occur with overdose or chronic high‑dose use, potentially leading to liver failure. Rare severe skin reactions such as Stevens‑Johnson syndrome and anaphylaxis have also been reported, requiring immediate medical attention.

Paracetamol Ratiopharm should be avoided in individuals with known hypersensitivity to paracetamol, severe liver disease, or those who have experienced serious adverse reactions to the drug. Patients on certain anticoagulants or with chronic alcohol use should consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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