Product image of Paracetamol Spharma (Paracetamol) supplied by GNH India

Paracetamol Spharma

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamol Spharma (Paracetamol)

Paracetamol, the active ingredient in Paracetamol Spharma, is an analgesic and antipyretic presented as a standard tablet for oral administration. It works by lowering elevated body temperature and alleviating mild to moderate pain, making it suitable for use in adults, adolescents and children when appropriate dosing is applied under medical guidance and careful monitoring.

GNH India supplies Paracetamol Spharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality assurance and regulatory compliance across all markets.

Manufacturer / TM Owner

Socium Pharma Bv

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Indications & Clinical Uses

Paracetamol is an analgesic and antipyretic used to manage pain and fever across several common conditions.

  • Fever: Reduces elevated body temperature in acute febrile illnesses.
  • Headache: Relieves tension‑type and mild migraine headaches.
  • Musculoskeletal pain: Alleviates aches associated with back strain, sprains and arthritis.
  • Toothache: Provides temporary relief of dental pain.
  • Post‑operative pain: Controls mild to moderate pain after minor surgical procedures.

How It Works

  • Paracetamol exerts its effect primarily by inhibiting cyclo‑oxygenase enzymes (COX‑1 and COX‑2) in the central nervous system, which reduces the synthesis of prostaglandins involved in pain signalling and thermoregulation. This peripheral and central action lowers the pain threshold and resets the hypothalamic set‑point for body temperature, providing analgesic and antipyretic effects without significant anti‑inflammatory activity.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: Mild gastrointestinal discomfort.
  • Skin rash: Transient erythema or urticaria.
  • Headache: Occasional worsening of headache.
  • Elevated liver enzymes: Minor, reversible changes.
  • Dizziness: Light‑headed sensation.
  • Insomnia: Difficulty falling asleep.

Serious or Rare Side Effects

  • Hepatotoxicity: Severe liver injury, especially with overdose.
  • Stevens‑Johnson syndrome: Rare severe skin reaction.
  • Anaphylaxis: Immediate hypersensitivity requiring emergency care.
  • Blood dyscrasias: Agranulocytosis or thrombocytopenia.
  • Renal impairment: Acute kidney injury in susceptible individuals.
  • Hypotension: Uncommon drop in blood pressure.

Precautions & Warnings

Paracetamol should be used with attention to safety considerations.

  • Assess liver function: Avoid use in patients with severe hepatic impairment.
  • Limit alcohol intake: Concomitant alcohol increases risk of liver toxicity.
  • Use lowest effective dose: Reduce exposure while achieving therapeutic effect.
  • Monitor in children: Dose must be weight‑based and age‑appropriate.
  • Pregnancy and lactation: Consult a healthcare professional before use.
  • Store at ambient temperature: Keep below 25 °C in the original packaging, protected from moisture.

Avoid Interactions

Paracetamol may interact with other medicines, requiring attention to potential effects.

Major Interactions (Avoid)

  • Alcohol: Increases risk of hepatotoxicity.
  • Warfarin: May potentiate anticoagulant effect, raising bleeding risk.
  • Carbamazepine: Can reduce paracetamol efficacy through enzyme induction.

Moderate Interactions (Monitor Closely)

  • Isoniazid, Phenytoin, Rifampicin: May alter paracetamol metabolism.
  • Oral contraceptives: May experience reduced contraceptive effectiveness.
  • Antiepileptic drugs: May increase hepatic enzyme activity, affecting drug levels.

Frequently Asked Questions

Paracetamol Spharma is used to relieve mild to moderate pain such as headaches, toothaches, musculoskeletal discomfort, and to reduce fever associated with common infections. It is an analgesic and antipyretic suitable for adults and children when prescribed at appropriate doses.

Paracetamol works by inhibiting cyclo‑oxygenase enzymes in the central nervous system, which lowers the production of prostaglandins that mediate pain and regulate body temperature. This dual action provides analgesic relief and antipyretic effect without significant anti‑inflammatory activity.

The dose of Paracetamol Spharma is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and any relevant medical history. The prescriber will select the appropriate strength and frequency to achieve therapeutic benefit while minimizing risk.

Paracetamol is generally considered compatible with pregnancy and lactation when used at the lowest effective dose for the shortest duration. However, pregnant or breastfeeding individuals should consult their healthcare provider before starting therapy to confirm safety for their specific situation.

To order Paracetamol Spharma, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Paracetamol Spharma provides analgesic and antipyretic effects without significant anti‑inflammatory activity, whereas ibuprofen adds anti‑inflammatory properties but carries a higher risk of gastrointestinal irritation and renal effects. Choice between the two depends on the clinical need, patient tolerance and any contraindications.

Paracetamol Spharma tablets should be stored at ambient temperature, preferably below 25 °C, in the original packaging to protect from moisture and light. Keep the product out of reach of children and do not use after the expiry date indicated on the label.

Paracetamol Spharma is administered orally, typically as a tablet swallowed with water. The exact route and timing are determined by the prescriber, who may advise taking it with or without food based on the patient’s comfort and therapeutic goals.

The most serious risks include severe liver injury (hepatotoxicity) especially with overdose or chronic high‑dose use, and rare hypersensitivity reactions such as Stevens‑Johnson syndrome or anaphylaxis. Prompt medical attention is required if signs of liver dysfunction or severe allergic reactions appear.

Paracetamol Spharma should be avoided in individuals with known hypersensitivity to paracetamol, severe hepatic impairment, or those who regularly consume excessive alcohol. Patients with certain metabolic disorders or who are taking interacting medications should consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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