Paracetamolo Kabi (Paracetamol)

Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which lowers the production of prostaglandins responsible for pain signaling and fever generation. This central action reduces the hypothalamic temperature set‑point and diminishes nociceptive transmission, resulting in analgesic and antipyretic effects.

The appropriate dose of Paracetamolo Kabi is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and renal or hepatic function. Healthcare professionals calculate the exact infusion rate and total amount required for each individual case.

Safety data for intravenous paracetamol in pregnancy and lactation are limited, and the product’s pregnancy category is not established. Clinicians should weigh potential benefits against risks and consider alternative therapies when treating pregnant or nursing patients.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Compared with oral paracetamol, the intravenous form delivers the drug directly into the bloodstream, achieving faster onset of action and reliable plasma concentrations, which is advantageous in patients unable to take oral medication. It differs from NSAIDs by lacking significant anti‑inflammatory activity and having a lower risk of gastrointestinal irritation.

Paracetamolo Kabi must be stored at 2‑8 °C in a refrigerator, protected from light. The solution should not be frozen or shaken. Before use, inspect the vial for particulate matter or discoloration and allow it to reach room temperature if required for administration.

The product is given by intravenous infusion under the supervision of qualified healthcare personnel. The infusion rate and total volume are set according to the prescriber’s instructions, typically using a calibrated infusion pump to ensure accurate delivery.

Serious risks include anaphylactic reactions, severe hepatic injury especially with overdose, and rare dermatologic conditions such as Stevens‑Johnson syndrome. Prompt recognition of these events and immediate medical intervention are essential.

Paracetamolo Kabi should be avoided in patients with known hypersensitivity to paracetamol or any component of the formulation, in individuals with severe hepatic impairment, and in those for whom the risk of serious adverse reactions outweighs the therapeutic benefit.