Product image of Paracetamolo Pensa Pharma (Paracetamol) supplied by GNH India

Paracetamolo Pensa Pharma

Active Ingredient:
Paracetamol
Origin:
EU

Paracetamolo Pensa Pharma (Paracetamol)

Paracetamol, the active ingredient in Paracetamolo Pensa Pharma, is an analgesic and antipyretic presented as an oral tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children when appropriate dosing is applied.

GNH India supplies Paracetamolo Pensa Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for regulated markets. Its distribution network ensures timely delivery across Europe, Asia and the Americas.

Manufacturer / TM Owner

Towa Pharmaceutical S.P.A.

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Indications & Clinical Uses

Paracetamol is an analgesic and antipyretic that acts on the central nervous system to alleviate pain and fever.

  • Mild to moderate pain: provides relief from headaches, musculoskeletal discomfort, dental pain, and menstrual cramps.
  • Fever: reduces elevated body temperature associated with infections or inflammatory conditions.
  • Post‑operative pain: helps manage discomfort after minor surgical procedures.

How It Works

  • Paracetamol exerts its effect primarily by inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2 in the central nervous system, leading to reduced synthesis of prostaglandins that mediate pain and thermoregulation. The peripheral inhibition is weak, which accounts for its limited anti‑inflammatory activity. This central action lowers the pain threshold and resets the hypothalamic set‑point for body temperature.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild stomach upset.
  • Rash: mild skin irritation.
  • Headache: transient discomfort.
  • Dizziness: occasional light‑headedness.

Serious or Rare Side Effects

  • Severe liver injury: possible with overdose or pre‑existing liver disease.
  • Allergic reactions: anaphylaxis or severe skin reactions such as Stevens‑Johnson syndrome.
  • Blood disorders: agranulocytosis or thrombocytopenia (rare).

Precautions & Warnings

When using Paracetamolo Pensa Pharma, consider the following precautions to ensure safe use.

  • Dosage adjustment: reduce dose in patients with hepatic impairment.
  • Alcohol consumption: avoid excessive alcohol as it increases hepatotoxic risk.
  • Concurrent medications: review use of other paracetamol‑containing products to prevent overdose.
  • Pregnancy and lactation: use only if clearly needed and under medical advice.
  • Allergy history: discontinue if signs of hypersensitivity develop.
  • Store at ambient temperature: keep below 25 °C, in original packaging, protected from moisture.

Avoid Interactions

Paracetamol may interact with certain medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Warfarin: increased anticoagulant effect, monitor INR closely.
  • Isoniazid: heightened risk of liver toxicity.
  • Carbamazepine: may reduce paracetamol plasma levels.

Moderate Interactions (Monitor Closely)

  • Alcohol: additive hepatotoxicity.
  • Enzyme inducers (e.g., rifampicin, phenobarbital): may decrease effectiveness.
  • Other hepatotoxic drugs (e.g., methotrexate): monitor liver function.

Frequently Asked Questions

Paracetamolo Pensa Pharma contains paracetamol, an analgesic and antipyretic indicated for the relief of mild to moderate pain such as headaches, musculoskeletal aches, dental discomfort, and menstrual cramps, as well as for the reduction of fever associated with infections or inflammatory conditions.

Paracetamol works by inhibiting cyclooxygenase enzymes COX‑1 and COX‑2 within the central nervous system, which reduces the synthesis of prostaglandins that sensitize pain receptors and regulate body temperature. This central inhibition lowers pain perception and resets the hypothalamic set‑point for temperature, providing analgesic and antipyretic effects.

The appropriate dose of paracetamol is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and any existing medical factors. Dosage recommendations are provided on the product label and should be followed precisely to avoid under‑ or overdosing.

Paracetamol is generally considered the analgesic of choice during pregnancy and lactation when required, but it should only be used if clearly indicated and under medical supervision. The prescriber will weigh potential benefits against any theoretical risks to the fetus or infant.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Paracetamol and ibuprofen both relieve pain and fever, but they differ in mechanism and safety profile. Paracetamol primarily acts centrally with minimal anti‑inflammatory activity and carries a lower risk of gastrointestinal irritation, whereas ibuprofen is a non‑steroidal anti‑inflammatory drug (NSAID) that also reduces inflammation but may cause gastric upset and affect platelet function. Choice depends on the clinical situation and patient tolerance.

Store the tablets at ambient temperature, preferably below 25 °C, in the original packaging to protect them from moisture and light. Keep the product out of reach of children and avoid storing in humid or excessively hot environments to maintain potency.

Paracetamolo Pensa Pharma is administered orally. The tablet should be swallowed whole with a glass of water, unless the prescriber advises otherwise. It can be taken with or without food, and the exact timing and frequency are determined by the healthcare professional based on the individual’s therapeutic needs.

The most serious risk is hepatotoxicity, which can occur with overdose or in patients with pre‑existing liver disease, especially when combined with alcohol or other hepatotoxic agents. Rare but severe allergic reactions, such as anaphylaxis or Stevens‑Johnson syndrome, may also occur and require immediate medical attention.

Paracetamol should be avoided in individuals with known hypersensitivity to paracetamol or any of the product’s excipients, in patients with severe hepatic impairment, and in those who have taken other paracetamol‑containing products that could lead to an accidental overdose. Consultation with a healthcare professional is essential before use in these situations.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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