Product image of Paramax Comp (Paracetamol, Caffeine) supplied by GNH India

Paramax Comp

Active Ingredient:
Paracetamol, Caffeine
Origin:
EU

Paramax Comp (Paracetamol, Caffeine)

Paracetamol, the active ingredient in Paramax Comp, is an Analgesic/Antipyretic presented as a tablet for oral use. It treats mild to moderate pain and fever in adults and children. Caffeine, the secondary ingredient, acts as a central nervous system stimulant to enhance analgesic effect.

GNH India supplies Paramax Comp as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Vitabalans Oy

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Indications & Clinical Uses

Paramax Comp combines paracetamol and caffeine to address pain‑related pathways and fever management.

  • Headache: Reduces intensity and improves alertness.
  • Dental pain: Provides relief after procedures.
  • Musculoskeletal pain: Alleviates aches associated with strain or injury.
  • Fever: Lowers elevated body temperature.
  • Migraine (adjunct): Enhances the effect of standard migraine therapy.

How It Works

  • Paracetamol reduces fever and pain by inhibiting central cyclooxygenase enzymes, decreasing prostaglandin synthesis in the brain. Caffeine blocks adenosine receptors, producing mild central nervous system stimulation and increasing the analgesic absorption of paracetamol, which together improve pain relief and reduce perceived fatigue.

Side Effects

Paracetamol/caffeine combination therapy is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: Mild stomach upset.
  • Insomnia: Difficulty falling asleep.
  • Restlessness: Feeling of unease.
  • Increased heart rate: Palpitations in sensitive individuals.
  • Gastro‑intestinal discomfort: Mild abdominal pain.

Serious or Rare Side Effects

  • Allergic reaction: Rash, itching, swelling, or difficulty breathing.
  • Hepatotoxicity: Liver injury with excessive dosing.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Anaphylaxis: Rapid onset of life‑threatening allergic response.
  • Blood disorders: Unexplained bruising or bleeding.

Precautions & Warnings

When using Paramax Comp, consider the following safety measures:

  • Dose limitation: Do not exceed the maximum daily amount of paracetamol.
  • Liver health: Avoid use in patients with severe hepatic impairment.
  • Pregnancy: Use only if clearly needed and prescribed by a healthcare professional.
  • Drug interactions: Review concomitant medications for potential synergistic toxicity.
  • Caffeine sensitivity: Monitor for heightened stimulant effects in sensitive individuals.
  • Store at ambient temperature: Keep below 25°C, retain original packaging, and protect from moisture.

Avoid Interactions

Paramax Comp may interact with several medicines; monitoring is advised.

Major Interactions (Avoid)

  • Warfarin: Increased risk of bleeding due to enhanced anticoagulant effect.
  • Isoniazid: Heightened risk of liver toxicity.
  • Highly protein‑bound drugs: Potential displacement leading to altered plasma levels.

Moderate Interactions (Monitor Closely)

  • Antidepressants (SSRIs, SNRIs): May increase serotonin levels.
  • Antiepileptic drugs: Possible alteration of seizure threshold.
  • Diuretics: Enhanced caffeine‑induced diuresis.
  • Oral contraceptives: May reduce efficacy of contraceptive hormones.
  • Other analgesics containing paracetamol: Risk of cumulative overdose.

Frequently Asked Questions

Paramax Comp is a combination of paracetamol and caffeine indicated for the relief of mild to moderate pain such as headache, dental pain, musculoskeletal aches, and for the reduction of fever. It is commonly used when an added stimulant effect is desired to improve alertness while managing pain.

Paracetamol acts centrally by inhibiting cyclooxygenase enzymes in the brain, which reduces the synthesis of prostaglandins that mediate pain and fever. This action lowers the body’s temperature set‑point and diminishes the perception of pain.

The specific dose of Paramax Comp is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and any concomitant medications. Patients should follow the prescriber’s instructions and not exceed the recommended maximum daily amount of paracetamol.

Paracetamol is generally considered safe in pregnancy when used at recommended doses, but caffeine should be limited. Breastfeeding mothers should consult their healthcare provider, as small amounts of both ingredients can pass into breast milk. Use only if clearly needed and prescribed.

To order, submit an enquiry on the Paramax Comp product page at gnhindia.com, providing the required quantity and your institutional credentials. GNH India supplies hospitals, pharmacies and procurement teams worldwide, then confirms trade or institutional verification, and replies with pricing, availability, shipping details and any necessary import documentation.

Paramax Comp combines paracetamol with caffeine, which can enhance analgesic efficacy and reduce fatigue compared with paracetamol alone. The caffeine component may improve pain relief speed and increase alertness, but it also introduces stimulant‑related side effects that are not present with plain paracetamol.

Paramax Comp tablets should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain tablet integrity.

Paramax Comp is administered orally, typically as a whole tablet swallowed with water. It is intended for systemic absorption through the gastrointestinal tract. Patients should not crush or chew the tablet unless specifically instructed by a healthcare professional.

Serious risks include severe allergic reactions such as anaphylaxis, liver injury (hepatotoxicity) from excessive paracetamol intake, and rare skin disorders like Stevens‑Johnson syndrome. Immediate medical attention is required if symptoms such as rash, swelling, breathing difficulty, or jaundice develop.

Individuals with known hypersensitivity to paracetamol, caffeine, or any excipients, patients with severe liver disease, and those who exceed the recommended daily paracetamol limit should avoid Paramax Comp. It is also contraindicated in children under the age specified by local regulations without appropriate dosing guidance.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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