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Pause Injection

Active Ingredient:
Tranexamic Acid

Pause Injection (Tranexamic Acid) 100MG

Pause Injection is a prescription antifibrinolytic medication containing the active ingredient tranexamic acid at a strength of 100 mg/mL. Administered intravenously, it helps control or prevent excessive bleeding by stabilizing blood clots in the body. It functions by reversibly blocking lysine-binding sites on plasminogen, preventing its activation to plasmin and thereby inhibiting the degradation of fibrin clots.

Strength

100MG

Storage

Ambient

1
Pack/s
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Indications & Clinical Uses

  • Pause Injection is indicated for the treatment and prevention of excessive bleeding in various clinical scenarios. Key indications include the management of acute hemorrhage, surgical bleeding prophylaxis, trauma-associated hemorrhage, and severe bleeding episodes. It is also utilized in specific cases of heavy menstrual bleeding when intravenous administration is clinically necessary.

Side Effects

  • Common side effects of Pause Injection may include nausea, vomiting, diarrhea, and dizziness. More serious but less common adverse effects can include deep vein thrombosis, pulmonary embolism, visual disturbances, and hypersensitivity reactions. Patients should immediately report any chest pain, shortness of breath, or sudden vision changes to their healthcare provider.

Precautions & Warnings

  • Pause Injection is contraindicated in patients with active thromboembolic disease or a history of venous or arterial thrombosis. It should be used with caution in patients with renal impairment, as dosage adjustments may be necessary. Classified under Pregnancy Category B, it should only be administered during pregnancy if clearly needed and prescribed by a physician.

Avoid Interactions

  • Pause Injection may interact with hormonal contraceptives, as concurrent use can increase the risk of blood clots. It should be used cautiously with other hemostatic agents, such as factor IX complex concentrates or anti-inhibitor coagulant complexes, due to an elevated risk of thrombosis. Avoid combining with thrombolytic agents which may counteract its therapeutic effects.

Frequently Asked Questions

Pause Injection is primarily used to prevent or reduce excessive bleeding in various clinical situations, such as surgical procedures, trauma-associated hemorrhage, and other severe bleeding disorders.

It works as an antifibrinolytic agent by blocking the activation of plasminogen to plasmin. This action prevents the breakdown of fibrin clots, helping to stabilize blood clots and control bleeding.

The active ingredient in Pause Injection is tranexamic acid, formulated at a strength of 100 mg/mL for intravenous administration.

Pause Injection is classified as Pregnancy Category B. It should only be used during pregnancy if the potential benefits outweigh the risks and under the strict supervision of a healthcare professional.

Some common side effects include gastrointestinal symptoms like nausea, vomiting, and diarrhea, as well as dizziness. Serious side effects like blood clots are rare but require immediate medical attention.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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