Product image of Lactated Ringer’s Bradex (Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Sodium Lactate) supplied by GNH India

Lactated Ringer’s Bradex

Active Ingredient:
Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Sodium Lactate
Origin:
EU

Lactated Ringer’s Bradex (Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Sodium Lactate)

Potassium chloride, sodium chloride, calcium chloride dihydrate, and sodium lactate, the active ingredients in Lactated Ringer’s Bradex, are an IV electrolyte solution presented as an intravenous solution for intravenous use. It restores extracellular fluid volume and electrolyte balance in patients requiring fluid resuscitation, electrolyte replacement, or peri‑operative hydration.

GNH India supplies Lactated Ringer’s Bradex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bradex S.A.

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Indications & Clinical Uses

Lactated Ringer’s solution is used as an intravenous volume expander and electrolyte replenisher in several clinical situations.

  • Fluid resuscitation: Replenishes intravascular volume in patients with hypovolemia or shock.
  • Electrolyte replacement: Corrects deficits of sodium, potassium, calcium and lactate during acute losses.
  • Perioperative hydration: Maintains fluid and electrolyte balance before, during and after surgery.

How It Works

  • Lactated Ringer’s solution delivers sodium, potassium, calcium, and lactate ions directly into the bloodstream. The ions expand the extracellular fluid compartment, while lactate is metabolized by the liver to bicarbonate, helping to correct metabolic acidosis. Together, these components restore osmolarity, support cellular function, and maintain acid‑base equilibrium during fluid loss or surgical stress.

Side Effects

Adverse reactions may occur with any intravenous infusion. Most are mild, but serious events are possible.

Common Side Effects

  • Mild infusion site irritation or phlebitis.
  • Transient hyperkalemia.
  • Slight hypernatremia.
  • Elevated calcium levels.
  • Metabolic alkalosis from lactate conversion.
  • Peripheral edema.

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction.
  • Significant electrolyte imbalance leading to cardiac arrhythmia.
  • Pulmonary edema in volume‑overloaded patients.
  • Sepsis from contaminated solution.
  • Severe metabolic acidosis if lactate metabolism is impaired.

Precautions & Warnings

Careful assessment and monitoring are required when using Lactated Ringer’s solution.

  • Assess baseline electrolyte status: check serum Na+, K+, Ca2+ before infusion.
  • Monitor cardiac function: watch for arrhythmias, especially in patients with cardiac disease.
  • Use cautiously in renal failure: reduced excretion may cause electrolyte accumulation.
  • Avoid rapid large‑volume infusion in heart failure: risk of fluid overload.
  • Adjust infusion rate in liver dysfunction: impaired lactate metabolism can worsen acidosis.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Lactated Ringer’s solution can interact with other medications and solutions.

Major Interactions (Avoid)

  • Co‑administration with hypertonic saline: may cause severe hypernatremia.
  • Simultaneous infusion of calcium‑containing blood products and bicarbonate solutions: risk of precipitation.
  • Mixing with dextrose‑containing solutions: can lead to incompatibility and precipitation.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: may exacerbate electrolyte shifts; monitor serum levels.
  • ACE inhibitors or ARBs: potential for additive hypotensive effect.
  • NSAIDs: may affect renal handling of electrolytes; monitor kidney function.

Frequently Asked Questions

Lactated Ringer’s Bradex is an intravenous electrolyte solution used to restore extracellular fluid volume and correct electrolyte imbalances. It is commonly employed for fluid resuscitation in hypovolemic patients, electrolyte replacement after acute losses, and peri‑operative hydration to maintain stable physiologic conditions during surgery.

The solution contains sodium, potassium, calcium, and lactate ions. When infused, these ions expand the extracellular fluid compartment, while lactate is metabolized by the liver into bicarbonate, helping to correct metabolic acidosis. Together they re‑establish osmotic balance and support normal cellular function.

The prescribed dose of Lactated Ringer’s Bradex is determined by the treating clinician based on the patient’s clinical status, fluid losses, and electrolyte needs. Healthcare professionals calculate the appropriate volume and infusion rate for each individual case.

Safety data for Lactated Ringer’s Bradex in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Unlike normal saline, Lactated Ringer’s Bradex contains potassium, calcium, and lactate, providing a more physiologic electrolyte composition and a buffering capacity that can help correct mild metabolic acidosis. Normal saline lacks these ions and may lead to hyperchloremic acidosis when used in large volumes.

Lactated Ringer’s Bradex should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. Keep the solution in its original packaging until use to maintain sterility and stability.

The solution is administered intravenously, typically through a peripheral or central line. The infusion rate and total volume are set by the prescriber according to the patient’s fluid status, clinical condition, and monitoring parameters.

Serious risks include severe electrolyte disturbances such as hyperkalemia, hypernatremia, or hypercalcemia, which can precipitate cardiac arrhythmias, as well as anaphylactic reactions, pulmonary edema from fluid overload, and infection if the solution becomes contaminated.

Patients with known hypersensitivity to any component of the solution, those with severe renal impairment where electrolyte clearance is compromised, or individuals with conditions predisposing them to fluid overload (e.g., uncontrolled heart failure) should avoid this product unless a clinician determines it is absolutely necessary.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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