Product image of Lactated Ringer’s Injection Βιοσερ (Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Sodium Lactate) supplied by GNH India

Lactated Ringer’s Injection Βιοσερ

Active Ingredient:
Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Sodium Lactate
Origin:
EU

Lactated Ringer’s Injection Βιοσερ (Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Sodium Lactate)

Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate, Sodium Lactate, the active ingredient in Lactated Ringer’s Injection Βιοσερ, is an electrolyte solution presented as an injection solution for intravenous use. It restores extracellular fluid volume and electrolyte balance in patients requiring fluid resuscitation, dehydration, or peri‑operative management.

GNH India supplies Lactated Ringer’s Injection Βιοσερ as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres and pharmacies worldwide.

Manufacturer / TM Owner

Multi-Pharm Co Ltd

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Indications & Clinical Uses

  • Lactated Ringer’s solution is an intravenous electrolyte fluid used in several clinical situations involving fluid and electrolyte deficits.
  • Fluid resuscitation: restores circulating volume and improves tissue perfusion in hypovolemic patients.
  • Electrolyte replacement: corrects deficits of sodium, potassium, and calcium during acute losses.
  • Dehydration: rehydrates individuals with fluid loss from illness, fasting, or excessive sweating.
  • Perioperative fluid management: maintains hemodynamic stability and electrolyte balance during surgery.

How It Works

  • Lactated Ringer’s solution supplies sodium, potassium, calcium, and chloride ions together with lactate, which is metabolized by the liver to bicarbonate, providing a mild alkalinizing effect. The combined electrolytes expand the extracellular fluid compartment, correcting osmotic imbalances and supporting normal cellular function while the generated bicarbonate helps buffer metabolic acidosis.

Side Effects

Adverse reactions may occur with any intravenous infusion. Most are mild and transient, but serious events are possible.

Common Side Effects

  • Injection site pain or irritation
  • Mild hyperkalemia
  • Mild hypernatremia
  • Transient hypertension
  • Mild metabolic alkalosis
  • Phlebitis or vein inflammation

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction
  • Severe hyperkalemia leading to cardiac arrhythmia
  • Severe hypernatremia causing neurologic symptoms
  • Fluid overload with pulmonary edema
  • Severe metabolic acidosis if lactate metabolism is impaired
  • Life‑threatening electrolyte imbalance causing cardiac arrest

Precautions & Warnings

Proper assessment and monitoring are essential when administering Lactated Ringer’s solution.

  • Baseline electrolyte assessment: check serum Na+, K+, Ca2+ before infusion.
  • Cardiac monitoring: observe rhythm and blood pressure during administration.
  • Adjust infusion rate in renal or cardiac failure to avoid overload.
  • Contraindicated in patients with severe hyperkalemia or hypercalcemia.
  • Use caution in neonates, elderly, and patients with liver dysfunction.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Lactated Ringer’s solution can interact with other medications that affect electrolyte balance or calcium levels.

Major Interactions (Avoid)

  • Potassium‑sparing diuretics: increase risk of hyperkalemia.
  • Calcium‑containing IV solutions: may cause calcium precipitation.
  • Blood products with citrate: alter calcium homeostasis.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: enhance potassium retention.
  • NSAIDs: may impair renal function and affect fluid balance.
  • Loop diuretics: cause rapid electrolyte shifts requiring close monitoring.

Frequently Asked Questions

Lactated Ringer’s Injection is an intravenous electrolyte solution used to restore fluid volume and replace lost electrolytes in patients who are dehydrated, undergoing surgery, or experiencing hypovolemia due to trauma or illness. It helps maintain hemodynamic stability and supports normal cellular function.

The solution contains sodium, potassium, calcium, and chloride ions, plus lactate. Lactate is metabolized by the liver into bicarbonate, providing a mild alkalinizing effect. Together, these components expand the extracellular fluid space, correct electrolyte imbalances, and assist in buffering metabolic acidosis.

The dose of Lactated Ringer’s Injection is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and electrolyte status. The healthcare professional selects the appropriate volume and infusion rate to achieve the desired therapeutic effect.

Safety data for Lactated Ringer’s Injection in pregnancy and lactation are limited. It is generally considered compatible with maternal and fetal health when clinically indicated, but the prescriber should evaluate the risk‑benefit profile for each individual patient.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain handling if needed), and import documentation.

Lactated Ringer’s contains balanced electrolytes and lactate, which is converted to bicarbonate, offering a mild alkalinizing effect. Normal saline is a simple NaCl solution without potassium, calcium, or lactate, and may cause a higher risk of hyperchloremic acidosis when used in large volumes. Choice depends on the clinical scenario and electrolyte goals.

The product should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. Keep the vial in its original packaging until use and inspect for particulate matter or discoloration before administration.

Lactated Ringer’s Injection is given intravenously, either as a continuous infusion or a controlled bolus, according to the prescriber’s instructions. Administration sets should be sterile, and infusion rates are adjusted based on the patient’s fluid status and monitoring parameters.

Serious risks include severe electrolyte disturbances such as hyperkalemia or hypernatremia, fluid overload leading to pulmonary edema, and rare anaphylactic reactions. Continuous monitoring of vital signs, cardiac rhythm, and serum electrolytes helps mitigate these risks.

Patients with known hypersensitivity to any component, severe hyperkalemia, severe hypercalcemia, or those in whom rapid fluid overload would be dangerous (e.g., severe heart failure) should not receive Lactated Ringer’s Injection. The prescriber must evaluate each case individually.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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