PROTOPIC Salbe 0.1 % (Tacrolimus Ointment) 0.1% x 60g

Tacrolimus, the active ingredient in PROTOPIC Salbe, works by binding to the cytoplasmic protein FKBP-12. This forms a complex that inhibits calcineurin, a phosphatase involved in the activation of T-cells. By inhibiting calcineurin, Tacrolimus reduces the production of inflammatory cytokines, thereby alleviating skin inflammation and symptoms of atopic dermatitis.

The dosage of PROTOPIC Salbe is determined by a healthcare provider based on the patient's condition and response to treatment. Typically, it is applied once or twice daily in a thin layer to the affected skin areas until symptoms improve. The duration of treatment should be as short as necessary to control the symptoms.

The safety of PROTOPIC Salbe during pregnancy or breastfeeding has not been fully established. It is classified as a Category C drug, meaning that animal studies have shown adverse effects on the fetus, but there are no adequate studies in humans. Women who are pregnant or breastfeeding should consult their healthcare provider before using this medication.

To order PROTOPIC Salbe from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will then provide pricing, availability, shipping details, and the necessary import paperwork.

PROTOPIC Salbe is a topical calcineurin inhibitor that is particularly useful for moderate to severe atopic dermatitis when conventional treatments like corticosteroids are ineffective or cause adverse effects. Unlike corticosteroids, it does not cause skin thinning with prolonged use. However, it should be used with caution due to its immunosuppressive properties and potential for serious side effects.

PROTOPIC Salbe should be stored below 25°C, in the original packaging, and protected from moisture and heat. It should be kept out of reach of children. Avoid freezing the ointment and ensure that it is not exposed to direct sunlight. Always follow the storage instructions provided on the packaging to maintain the medication's effectiveness.

PROTOPIC Salbe should be applied in a thin layer to the affected skin areas once or twice daily, as directed by a healthcare provider. It is important to avoid applying the ointment to areas with active infections or broken skin. The hands should be washed after application, unless the hands are being treated, in which case they should be washed only after the ointment has been absorbed.

The most serious risks associated with PROTOPIC Salbe include an increased risk of skin cancer or lymphoma with prolonged use, severe allergic reactions, and eye irritation if the product comes into contact with the eyes. Patients should monitor for signs of infection, such as folliculitis or herpes simplex, and report any unusual symptoms to their healthcare provider immediately.

PROTOPIC Salbe should not be used by individuals with known hypersensitivity to Tacrolimus or any of the excipients in the ointment. It is also not recommended for patients with active skin infections, those with weakened immune systems, or children under 2 years of age. Patients should consult their healthcare provider to determine if PROTOPIC Salbe is appropriate for their specific condition.