Product image of Rcifax 550 (Rifaximin) 550mg Tablet supplied by GNH India

Rcifax 550

Active Ingredient:
Rifaximin
Form:
Tablet
Brand:
Rcifax 550
Origin:
India

Rcifax 550 (Rifaximin Tablet) 550mg

Rifaximin, the active ingredient in Rcifax 550, is an intestinal antibiotic presented as a 550mg tablet for oral use. It is designed to treat conditions such as traveller's diarrhoea, irritable bowel syndrome with diarrhoea (IBS-D), and to reduce the risk of hepatic encephalopathy in adults.

GNH India supplies Rcifax 550 as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Strength

550mg

Pack Size

100s

Storage

15-25°

Manufacturer / TM Owner

LUPIN LTD

1
Pack/s
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Indications & Clinical Uses

Rcifax 550 is an intestinal antibiotic used to treat various gastrointestinal conditions. It is effective in managing the following conditions:

  • Traveller's diarrhoea: Treats non-invasive diarrhoea caused by Escherichia coli in adults and children over 12 years old.
  • Irritable bowel syndrome with diarrhoea (IBS-D): Reduces symptoms of diarrhoea in adults with IBS.
  • Hepatic encephalopathy: Reduces the risk of recurrence in adults with liver failure.
  • Clostridioides difficile infection: Off-label use for managing this infection.

How It Works

  • Rifaximin works by inhibiting bacterial RNA synthesis. It binds to the beta-subunit of DNA-dependent RNA polymerase, which prevents bacteria from producing essential proteins. This action is localized in the gut, minimizing systemic absorption and targeting harmful bacteria directly in the digestive tract.

Side Effects

Rcifax 550 may cause several side effects, ranging from common to serious or rare. Common Side Effects:

  • Gastrointestinal upset: Nausea, vomiting, or abdominal pain.
  • Headache: Mild to moderate headaches.
  • Dizziness: Feeling lightheaded or unsteady.
  • Fatigue: General tiredness or weakness.

Serious or Rare Side Effects

  • Allergic reactions: Rash, itching, or swelling, which may indicate an allergic response.
  • Liver enzyme abnormalities: Elevated liver enzymes, which may require monitoring.
  • Clostridioides difficile-associated diarrhoea: Severe diarrhoea due to bacterial imbalance.
  • Peripheral neuropathy: Nerve damage leading to numbness or tingling in extremities.

Precautions & Warnings

Rcifax 550 should be used with caution and under medical supervision. Important precautions include:

  • Avoid in patients with bloody diarrhoea, fever, or suspected invasive pathogens: Not suitable for severe or complicated diarrhoea.
  • Monitor liver function: Regularly check liver enzymes in patients with liver impairment.
  • Consult a doctor if pregnant or breastfeeding: Safety during pregnancy and breastfeeding has not been fully established.
  • Avoid in patients with known hypersensitivity: Do not use if allergic to rifaximin or other rifamycins.
  • Store below 25°C: Keep in the original pack, protect from moisture.

Avoid Interactions

Rcifax 550 may interact with other medications, requiring careful monitoring. Major Interactions (Avoid):

  • P-gp inhibitors: May increase systemic absorption of rifaximin, leading to higher plasma concentrations.
  • CYP3A4 inducers: May reduce the effectiveness of rifaximin by altering its metabolism.

Moderate Interactions (Monitor Closely)

  • Anticoagulants: May require dose adjustment to prevent bleeding risks.
  • Oral contraceptives: May reduce the effectiveness of birth control pills.
  • Other antibiotics: May alter the gut microbiota, affecting the efficacy of rifaximin.

Frequently Asked Questions

Rcifax 550 is used to treat traveller's diarrhoea, irritable bowel syndrome with diarrhoea (IBS-D), and to reduce the risk of hepatic encephalopathy in adults. It is an intestinal antibiotic that targets harmful bacteria in the gut, helping to restore digestive balance and comfort.

Rifaximin works by inhibiting bacterial RNA synthesis. It binds to the beta-subunit of DNA-dependent RNA polymerase, preventing bacteria from producing essential proteins. This action is localized in the gut, minimizing systemic absorption and targeting harmful bacteria directly in the digestive tract.

The dosage of Rcifax 550 is determined by a healthcare professional based on the condition being treated. For traveller's diarrhoea, it is typically 200 mg three times daily for 3 days. For hepatic encephalopathy, the usual dose is 550 mg twice daily. Always follow the prescribed dosage.

The safety of Rcifax 550 during pregnancy and breastfeeding has not been fully established. Consult your doctor before using this medication if you are pregnant or breastfeeding. Your healthcare provider will weigh the benefits and potential risks to determine if it is suitable for you.

To order Rcifax 550 from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will reply with pricing, availability, shipping, and the necessary import paperwork.

Rcifax 550 is a gut-specific antibiotic with minimal systemic absorption, making it ideal for treating gastrointestinal conditions. Unlike broad-spectrum antibiotics, it targets harmful bacteria in the gut without significantly affecting the rest of the body. This localized action reduces the risk of systemic side effects and antibiotic resistance.

Rcifax 550 should be stored below 25°C, in the original pack, and protected from moisture. Ensure the container is tightly closed and kept out of reach of children. Follow the storage instructions provided with the medication to maintain its effectiveness and safety.

Rcifax 550 is administered orally, with or without food. The tablets should be swallowed whole with a glass of water. Follow the dosage instructions provided by your healthcare professional. Do not crush or chew the tablets unless directed to do so.

The most serious risks associated with Rcifax 550 include allergic reactions, liver enzyme abnormalities, and Clostridioides difficile-associated diarrhoea. Seek immediate medical attention if you experience severe diarrhoea, rash, itching, swelling, or signs of liver dysfunction while taking this medication.

Rcifax 550 should not be used by individuals with known hypersensitivity to rifaximin or other rifamycins. It is also not suitable for patients with bloody diarrhoea, fever, or suspected invasive pathogens. Consult your healthcare provider to determine if Rcifax 550 is appropriate for your condition.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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