Product image of REGRANEX Gel 0.01% (Becaplermin) 0.01% x 15g GEL supplied by GNH India

REGRANEX Gel 0.01%

Active Ingredient:
Becaplermin
Form:
GEL
Brand:
REGRANEX Gel 0.01%
Origin:
USA

REGRANEX Gel 0.01% (Becaplermin GEL) 0.01% x 15g

Becaplermin, the active ingredient in REGRANEX Gel 0.01%, is a recombinant human platelet-derived growth factor (PDGF) presented as a 0.01% gel for topical use. It is used to promote the healing of diabetic foot ulcers in patients with adequate blood flow to the affected area.

GNH India supplies REGRANEX Gel 0.01% as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Strength

0.01% x 15g

Pack Size

1s

Storage

2-8°

Manufacturer / TM Owner

Smith & Nephew, Inc.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

REGRANEX Gel 0.01% is indicated for the treatment of diabetic foot ulcers. It is used as part of a comprehensive treatment plan that includes good ulcer care, such as removing dead tissue, using special footwear, and treating any infections that may develop.

  • Diabetic foot ulcer: Promotes healing and new skin growth in diabetic foot ulcers.
  • Wound healing: Helps in the repair and replacement of dead skin and other tissues.
  • Granulation tissue formation: Attracts cells that repair wounds and helps to close and heal the ulcer.

How It Works

  • REGRANEX Gel 0.01% works by binding to PDGF receptors on fibroblasts and smooth-muscle cells, stimulating chemotaxis, proliferation, and extracellular matrix production. This promotes granulation tissue formation and wound healing, aiding in the repair of diabetic foot ulcers.

Side Effects

REGRANEX Gel 0.01% may cause side effects, although not everyone gets them. Common Side Effects:

  • Skin rash or redness at the application site.
  • Itching or burning sensation where the medicine was applied.
  • Mild irritation or discomfort.

Serious or Rare Side Effects

  • Severe allergic reactions, including hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.
  • Increased size of the ulcer or worsening symptoms.
  • Skin cancer or tumors at the application site.
  • Severe skin reactions, such as blistering or peeling.

Precautions & Warnings

REGRANEX Gel 0.01% should be used with caution and under medical supervision. Inform your healthcare provider if you have any of the following conditions or are taking any other medications.

  • Inform your doctor: If you have poor blood flow to your legs or feet, or a history of cancer.
  • Avoid use: If you have skin cancer or tumors at the affected area.
  • Pregnancy and breastfeeding: Inform your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.
  • Allergic reactions: Stop using REGRANEX Gel 0.01% and seek medical help if you experience signs of an allergic reaction.
  • Storage: Store at 2-8°C: Keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

REGRANEX Gel 0.01% may interact with other medications or conditions. Major Interactions (Avoid):

  • Avoid use: If you have skin cancer or tumors at the application site.
  • Allergic reactions: Stop using REGRANEX Gel 0.01% and seek medical help if you experience signs of an allergic reaction.

Moderate Interactions (Monitor Closely)

  • Inform your doctor: If you have poor blood flow to your legs or feet, or a history of cancer.
  • Pregnancy and breastfeeding: Inform your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.
  • Other medications: Inform your doctor about all medications you are taking to avoid potential interactions.

Frequently Asked Questions

REGRANEX Gel 0.01% is used to promote the healing of diabetic foot ulcers in patients with adequate blood flow to the affected area. It is part of a comprehensive treatment plan that includes good ulcer care, such as removing dead tissue, using special footwear, and treating any infections that may develop.

Becaplermin, the active ingredient in REGRANEX Gel 0.01%, is a recombinant human platelet-derived growth factor (PDGF). It works by binding to PDGF receptors on fibroblasts and smooth-muscle cells, stimulating chemotaxis, proliferation, and extracellular matrix production. This promotes granulation tissue formation and wound healing, aiding in the repair of diabetic foot ulcers.

The usual dose of REGRANEX Gel 0.01% is determined by your healthcare provider based on the size of your ulcer. It is typically applied once a day to the ulcer. Your doctor will examine your ulcer every 1 to 2 weeks and may adjust the amount of gel as your ulcer heals and grows smaller.

The safety of REGRANEX Gel 0.01% during pregnancy or breastfeeding has not been established. Inform your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. Your doctor will discuss the potential risks and benefits of using REGRANEX Gel 0.01% in your specific situation.

To order REGRANEX Gel 0.01% from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will reply with pricing, availability, shipping, and the import paperwork.

REGRANEX Gel 0.01% is a recombinant human platelet-derived growth factor (PDGF) that promotes wound healing by stimulating granulation tissue formation. It is specifically indicated for diabetic foot ulcers. Other treatments may include debridement, offloading devices, and antibiotics for infections. Your healthcare provider will determine the most appropriate treatment plan for your specific condition.

REGRANEX Gel 0.01% should be stored in the refrigerator at 2 to 8 degrees C (36 to 46 degrees F). Do not freeze the gel. Keep the tube tightly capped when not in use. Do not use REGRANEX Gel 0.01% past the expiration date. Protect the gel from light and ensure it is kept out of reach of children.

REGRANEX Gel 0.01% is applied topically to the ulcer. Wash your hands thoroughly before use. Squeeze the prescribed amount of gel onto a clean, non-absorbable surface like wax paper. Use a clean cotton swab, tongue depressor, or other applicator to spread the gel over the ulcer surface in an even layer. Cover the ulcer with a saline-moistened gauze dressing. After 12 hours, remove the gauze dressing and rinse the ulcer with saline or water to remove excess gel. Apply a new piece of saline-moistened gauze dressing to the ulcer.

The most serious risks to watch for with REGRANEX Gel 0.01% include severe allergic reactions, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat. Other serious risks include an increase in the size of the ulcer, worsening symptoms, and the development of skin cancer or tumors at the application site. Stop using REGRANEX Gel 0.01% and seek medical help immediately if you experience any of these symptoms.

REGRANEX Gel 0.01% should not be used by individuals who are allergic to becaplermin or any of the other ingredients in the gel. It should also not be used by individuals with skin cancer or tumors at the affected area. Inform your doctor if you have poor blood flow to your legs or feet, or a history of cancer, before using REGRANEX Gel 0.01%. Your doctor will determine if REGRANEX Gel 0.01% is appropriate for your specific condition.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.