Sandimmun Neoral- 100mg (Ciclosporin Capsule) 100 MG

Ciclosporin binds to the intracellular protein cyclophilin, and the resulting complex inhibits the enzyme calcineurin. This blocks activation of nuclear factor of activated T‑cells (NF‑AT), reducing interleukin‑2 production and suppressing T‑cell–mediated immune responses.

The dose of ciclosporin is individualized. A qualified prescriber determines the appropriate amount and schedule based on the patient’s condition, weight, kidney function, and other clinical factors. No fixed regimen should be assumed without professional guidance.

Ciclosporin is classified as Pregnancy Category C, indicating that risk cannot be ruled out. It should be used only if the potential benefit justifies the potential fetal risk. Limited data are available for breastfeeding, so a risk‑benefit assessment with a healthcare provider is essential.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

The main alternative is tacrolimus, another calcineurin inhibitor. Both suppress T‑cell activation, but tacrolimus often has a different side‑effect profile, such as a higher incidence of neurotoxicity, while ciclosporin is more commonly associated with nephrotoxicity and hypertension. Choice depends on clinical response, tolerability and physician preference.

Store the capsules at ambient temperature, preferably below 25 °C, in the original container. Protect them from moisture, direct sunlight and extreme heat. Keep the product out of reach of children and do not use after the expiry date.

The medication is taken orally. Swallow each capsule whole with a glass of water, preferably on an empty stomach unless directed otherwise by a healthcare professional. Do not crush, split or chew the capsule.

Serious risks include nephrotoxicity (decline in kidney function), severe infections due to immunosuppression, hepatotoxicity (liver enzyme elevations), and an increased risk of certain malignancies such as lymphomas and skin cancers. Patients should be monitored regularly for these complications.

Ciclosporin is contraindicated in patients with known hypersensitivity to ciclosporin or any of its excipients, uncontrolled hypertension, severe renal impairment, and active uncontrolled infections. Caution is also advised for individuals with a history of malignancy or severe liver disease.