Product image of Isotonische Kochsalzlösung (Sodium Chloride) supplied by GNH India

Isotonische Kochsalzlösung

Active Ingredient:
Sodium Chloride
Origin:
EU

Isotonische Kochsalzlösung (Sodium Chloride)

Sodium Chloride, the active ingredient in Isotonische Kochsalzlösung, is an electrolyte solution presented as an injection solution for intravenous use. It helps restore extracellular fluid volume and sodium chloride balance in patients requiring fluid replacement, electrolyte correction, or blood volume expansion.
GNH India supplies Isotonische Kochsalzlösung as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Fresenius Kabi Deutschland Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Isotonische Kochsalzlösung is an isotonic electrolyte solution used in clinical situations that involve fluid and electrolyte management.
  • Fluid replacement: Restores intravascular volume in patients with dehydration, hemorrhage, or surgical loss.
  • Electrolyte balance: Provides sodium and chloride to correct hyponatremia or chloride deficits.
  • Blood volume expansion: Increases circulating volume during shock or sepsis to support organ perfusion.

How It Works

  • Sodium chloride injection delivers Na+ and Cl‑ ions directly into the bloodstream, increasing extracellular osmolarity and drawing water into the vascular compartment. This osmotic effect expands plasma volume, normalizes serum sodium levels, and supports hemodynamic stability without altering cellular metabolism.

Side Effects

Isotonische Kochsalzlösung may be associated with adverse reactions following intravenous administration.

Common Side Effects

  • Injection site pain or irritation.
  • Mild hypernatremia leading to thirst.
  • Transient hypertension.
  • Peripheral edema.
  • Nausea or mild gastrointestinal discomfort.
  • Headache.

Serious or Rare Side Effects

  • Severe hypernatremia with neurologic symptoms.
  • Fluid overload causing pulmonary edema.
  • Anaphylactic or severe allergic reaction.
  • Significant electrolyte imbalance (e.g., hyperchloremic acidosis).
  • Hemolysis (rare with improper administration).
  • Cardiac arrhythmias due to rapid volume shifts.

Precautions & Warnings

  • When using Isotonische Kochsalzlösung, clinicians should consider patient‑specific factors and monitor for complications.
  • Renal impairment: Adjust volume and monitor serum electrolytes.
  • Cardiac failure: Avoid excessive infusion that may worsen congestion.
  • Hypernatremia risk: Check baseline sodium levels before administration.
  • Pediatric use: Calculate dose based on weight and monitor closely.
  • Concurrent diuretics: Observe for rapid electrolyte shifts.
  • Store at 2-8°C: Keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Isotonische Kochsalzlösung can interact with other therapies that affect fluid and electrolyte balance.

Major Interactions (Avoid)

  • Co‑administration with hypertonic saline solutions: Increases risk of severe hypernatremia.
  • Large‑volume blood product transfusions: May precipitate fluid overload.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: May cause rapid electrolyte changes; monitor sodium and potassium.
  • ACE inhibitors or ARBs: Potential for additive effects on blood pressure; observe hemodynamics.
  • Corticosteroids: May enhance sodium retention; watch for edema.

Frequently Asked Questions

Isotonische Kochsalzlösung is an intravenous sodium chloride solution used to replace lost fluids, correct electrolyte imbalances, and expand blood volume in patients with dehydration, hemorrhage, or shock. It provides a physiologic concentration of sodium and chloride to support circulatory stability.

The sodium chloride in the solution increases extracellular osmolarity, drawing water into the vascular space. This expands plasma volume, restores normal serum sodium and chloride concentrations, and helps maintain blood pressure and tissue perfusion without altering intracellular processes.

The prescribed dose of Isotonische Kochsalzlösung is determined by the treating clinician based on the patient’s fluid status, weight, and clinical condition. Dosage is individualized and administered under medical supervision.

Safety data for isotonic saline in pregnancy and lactation are limited, but the solution is generally considered compatible because it contains only sodium chloride, a naturally occurring electrolyte. Clinicians should assess the risk‑benefit ratio for each patient.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Compared with hypertonic or hypotonic solutions, isotonic sodium chloride closely matches plasma osmolarity, minimizing cellular shifts. It offers a balanced approach for volume expansion without the risks of electrolyte disturbances associated with more concentrated or diluted fluids.

The product should be stored at 2‑8 °C, kept in its original packaging, protected from light, and should not be frozen or shaken. Before use, inspect the vial for particulate matter and ensure the solution is clear.

It is administered intravenously by a qualified healthcare professional. The solution can be given as a bolus or continuous infusion, depending on the clinical indication and the patient’s hemodynamic status.

Serious risks include severe hypernatremia, fluid overload leading to pulmonary edema, and rare allergic reactions such as anaphylaxis. Monitoring of vital signs, fluid balance, and serum electrolytes is essential during therapy.

Patients with uncontrolled heart failure, severe renal impairment, or known hypersensitivity to sodium chloride solutions should avoid this product unless the benefits outweigh the risks and close monitoring is possible.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Sodium Chloride

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT