Product image of Isotonische Kochsalzlösung 0,9% Bernburg (Sodium Chloride) supplied by GNH India

Isotonische Kochsalzlösung 0,9% Bernburg

Active Ingredient:
Sodium Chloride
Origin:
EU

Isotonische Kochsalzlösung 0,9% Bernburg (Sodium Chloride)

Sodium Chloride, the active ingredient in Isotonische Kochsalzlösung 0,9% Bernburg, is an electrolyte presented as a 0.9% w/v injection solution for intravenous use. It is used to restore extracellular fluid volume and electrolyte balance in patients requiring fluid replacement, such as those with dehydration, blood loss, or peri‑operative needs.

GNH India supplies Isotonische Kochsalzlösung 0,9% Bernburg as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Burg Pharma Gmbh

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Indications & Clinical Uses

  • Isotonische Kochsalzlösung 0,9% Bernburg is an isotonic sodium chloride solution used for fluid and electrolyte management.
  • Dehydration: provides necessary fluid and electrolyte replacement to rehydrate patients.
  • Blood loss: restores intravascular volume after hemorrhage.
  • Peri‑operative care: supports volume status before and after surgery.

How It Works

  • Isotonische Kochsalzlösung 0,9% delivers sodium (Na⁺) and chloride (Cl⁻) ions directly into the bloodstream, increasing extracellular fluid osmolarity and drawing water into the vascular compartment. This osmotic effect expands plasma volume, corrects hyponatremia, and helps maintain acid‑base balance. The solution’s isotonic concentration matches physiological plasma, minimizing cellular shifts while providing a rapid source of electrolytes for volume resuscitation.

Side Effects

Adverse reactions to isotonic sodium chloride injection are generally uncommon but may occur.

Common Side Effects

  • Injection site pain: mild discomfort or burning at the infusion site.
  • Transient hypernatremia: temporary rise in serum sodium if infused rapidly.
  • Hypotension: possible drop in blood pressure with large-volume administration.
  • Edema: peripheral swelling due to fluid accumulation.

Serious or Rare Side Effects

  • Severe hypernatremia: marked elevation of serum sodium leading to neurological symptoms.
  • Anaphylactic reaction: rare allergic response with hives, airway swelling, or shock.
  • Fluid overload: pulmonary edema or heart failure exacerbation in susceptible patients.
  • Electrolyte imbalance: abnormal shifts causing cardiac arrhythmias.

Precautions & Warnings

When using Isotonische Kochsalzlösung 0,9% Bernburg, consider the following precautions to ensure safe administration.

  • Renal impairment: monitor fluid balance and serum electrolytes closely.
  • Cardiac failure: avoid excessive volumes that may precipitate decompensation.
  • Electrolyte disorders: assess baseline sodium levels before infusion.
  • Pediatric patients: calculate dose and volume carefully based on weight.
  • Pregnancy: use only if clearly indicated after risk‑benefit evaluation.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Isotonische Kochsalzlösung 0,9% may interact with other therapies; awareness of these interactions helps prevent complications.

Major Interactions (Avoid)

  • Concurrent hypertonic saline: risk of severe hypernatremia.
  • High‑dose diuretics (loop or thiazide): may cause marked electrolyte disturbances.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: large volumes can affect renal perfusion.
  • Corticosteroids: may increase fluid retention and edema.
  • Blood product transfusion: monitor for volume overload.

Frequently Asked Questions

Isotonische Kochsalzlösung 0,9% Bernburg is an isotonic sodium chloride injection used to replace lost fluids and electrolytes. It is indicated for patients who need rapid volume expansion, such as those with dehydration, acute blood loss, or who require peri‑operative fluid support during surgery.

The solution provides sodium (Na⁺) and chloride (Cl⁻) ions that increase the osmolarity of the extracellular compartment. This draws water into the vascular space, expanding plasma volume and correcting hyponatremia while maintaining acid‑base balance. Its isotonic concentration matches plasma, limiting cellular shifts.

The prescribed dose is individualized by the treating clinician based on the patient’s weight, clinical condition, and the extent of fluid loss. The prescriber calculates the required volume to achieve the desired plasma expansion and monitors the response during therapy.

Safety data for Isotonische Kochsalzlösung 0,9% in pregnancy and lactation are limited. It may be used when clearly needed, but the prescriber should evaluate the risk‑benefit ratio for each patient and consider alternative therapies if appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Isotonische Kochsalzlösung 0,9% contains only sodium and chloride, making it a pure saline solution, whereas Ringer's lactate also provides potassium, calcium and lactate. Saline is preferred when a simple isotonic fluid is needed, while Ringer's lactate may be chosen for patients requiring additional electrolytes and a more physiologic buffer.

Store the product at ambient temperature, below 25 °C, in its original sealed container. Protect it from direct sunlight, moisture and extreme temperatures. Inspect the vial for particulate matter or discoloration before use and discard if the seal is compromised.

The solution is administered intravenously, typically through a peripheral or central venous catheter. The prescriber determines the infusion rate and total volume based on the clinical scenario. Infusion sets should be primed to remove air, and the line should be monitored for signs of infiltration or adverse reactions.

Serious risks include severe hypernatremia, fluid overload leading to pulmonary edema, and rare anaphylactic reactions. Patients with compromised cardiac or renal function are particularly vulnerable, so close monitoring of fluid balance, vital signs and serum electrolytes is essential during therapy.

The solution should be avoided in patients with known hypersensitivity to sodium chloride, uncontrolled heart failure, severe renal impairment, or conditions where excessive fluid administration could worsen edema. Contraindications are determined by the prescriber based on the individual’s medical history.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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