Product image of Isotonische Kochsalzlösung Fresenius Kabi Deutschland (Sodium Chloride) supplied by GNH India

Isotonische Kochsalzlösung Fresenius Kabi Deutschland

Active Ingredient:
Sodium Chloride
Origin:
EU

Isotonische Kochsalzlösung Fresenius Kabi Deutschland (Sodium Chloride)

Sodium Chloride, the active ingredient in Isotonische Kochsalzlösung Fresenius Kabi Deutschland, is an electrolyte solution presented as an injection solution for intravenous, intramuscular or subcutaneous use. It restores extracellular fluid volume and electrolyte balance in patients who need fluid replacement or volume expansion.
GNH India supplies Isotonische Kochsalzlösung Fresenius Kabi Deutschland as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Fresenius Kabi Deutschland Gmbh

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Indications & Clinical Uses

Isotonische Kochsalzlösung is an isotonic electrolyte solution used in clinical situations that require fluid and electrolyte management.

  • Fluid replacement: restores intravascular volume in dehydration, hemorrhage or burns.
  • Electrolyte replenishment: supplies sodium and chloride to correct electrolyte deficits.
  • Volume expansion: increases circulating plasma volume during surgery or critical illness.

How It Works

  • Sodium Chloride injection provides an isotonic solution that expands the extracellular fluid compartment. The sodium and chloride ions distribute across cell membranes, increasing plasma osmolarity and drawing water into the vascular space, thereby correcting hypovolemia and normalising serum electrolyte concentrations.

Side Effects

Adverse reactions may occur with any parenteral solution.

Common Side Effects

  • Injection site pain or erythema.
  • Phlebitis or thrombophlebitis at the infusion site.
  • Mild hypernatremia if administered in excess.
  • Transient hypotension with rapid infusion.

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction.
  • Severe electrolyte imbalance leading to cardiac arrhythmia.
  • Pulmonary edema from fluid overload.
  • Sepsis related to contaminated solution.

Precautions & Warnings

Proper assessment and monitoring are essential when using isotonic saline.

  • Assess fluid status: evaluate volume needs before administration.
  • Monitor electrolytes: check serum sodium and chloride regularly.
  • Avoid rapid infusion in heart‑failure or renal‑impairment patients.
  • Use aseptic technique: ensure sterility of the injection site and solution.
  • Check compatibility: verify that the solution is compatible with other IV drugs.
  • Store below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Sodium Chloride solution can interact with other therapies that affect fluid or electrolyte balance.

Major Interactions (Avoid)

  • Co‑administration with hypertonic saline solutions.
  • Simultaneous infusion of potassium chloride without electrolyte monitoring.
  • Use with large volumes of other sodium‑rich fluids leading to overload.

Moderate Interactions (Monitor Closely)

  • Concurrent diuretic therapy may alter sodium balance.
  • Use with nephrotoxic agents requires renal function monitoring.
  • Simultaneous blood product transfusion may affect volume status.

Frequently Asked Questions

Isotonische Kochsalzlösung is an isotonic sodium chloride injection used to replace lost fluids, replenish sodium and chloride electrolytes, and expand circulating blood volume in patients with dehydration, blood loss, or during surgical procedures.

The solution delivers sodium and chloride ions in concentrations matching normal plasma. These ions increase extracellular osmolarity, drawing water into the vascular compartment, which restores intravascular volume and corrects electrolyte imbalances.

The prescribed dose is determined by the treating clinician based on the patient’s fluid status, electrolyte levels, and clinical condition. Dosing is individualized and should follow the healthcare professional’s instructions.

Sodium chloride is a naturally occurring electrolyte, and isotonic saline is generally considered compatible with pregnancy and lactation when clinically indicated. However, the prescriber should evaluate the risk‑benefit ratio for each individual case.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and required import documentation.

Isotonische Kochsalzlösung provides a standard 0.9% sodium chloride concentration, similar to other normal saline products. Differences may lie in manufacturing standards, packaging, and regulatory approvals. Clinical efficacy is comparable when used for fluid and electrolyte replacement.

Store the injection solution below 25 °C in its original packaging, protecting it from moisture and direct sunlight. Do not freeze. Inspect the vial for particulate matter or discoloration before use and follow aseptic techniques during preparation.

The solution is administered by intravenous, intramuscular, or subcutaneous injection. The route, rate, and volume are determined by the prescriber, who may use infusion pumps or manual injection techniques depending on the clinical situation.

Serious risks include anaphylactic reactions, severe electrolyte disturbances such as hypernatremia, and fluid overload leading to pulmonary edema or cardiac arrhythmias. Immediate medical attention is required if any of these occur.

Patients with known hypersensitivity to sodium chloride or any component of the formulation should avoid use. Caution is advised in individuals with severe heart failure, uncontrolled hypertension, or renal impairment where fluid overload could be hazardous.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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