Product image of Natriumchlorid-Lösung Deltamedica (Sodium Chloride) supplied by GNH India

Natriumchlorid-Lösung Deltamedica

Active Ingredient:
Sodium Chloride
Origin:
EU

Natriumchlorid-Lösung Deltamedica (Sodium Chloride)

Sodium chloride, the active ingredient in Natriumchlorid-Lösung Deltamedica, is an electrolyte solution presented as an intravenous solution for fluid and electrolyte replacement use. It restores extracellular sodium and chloride levels and expands intravascular volume when administered intravenously.

GNH India supplies Natriumchlorid-Lösung Deltamedica as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Deltamedica Gmbh

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Indications & Clinical Uses

Natriumchlorid-Lösung Deltamedica is used in clinical situations that require rapid restoration of fluid and electrolyte balance.

  • Hypovolemia: expands intravascular volume to improve circulatory stability.
  • Hyponatremia: provides sodium to correct low serum sodium concentrations.
  • Peri‑operative care: maintains electrolyte homeostasis during surgery.
  • Burn or trauma resuscitation: supplies isotonic fluid to replace losses.

How It Works

  • Sodium chloride solution delivers Na⁺ and Cl⁻ ions directly into the bloodstream, increasing extracellular osmolarity and plasma volume. The added sodium restores osmotic balance, promotes water retention in the vascular compartment, and supports normal cellular function, while chloride contributes to acid‑base regulation and electrical neutrality.

Side Effects

Sodium chloride intravenous infusion can be associated with a range of adverse reactions.

Common Side Effects

  • Infusion site irritation or pain.
  • Mild hypernatremia when administered in excess.
  • Fluid overload leading to peripheral edema.
  • Transient increase in blood pressure.
  • Electrolyte imbalance if not monitored.

Serious or Rare Side Effects

  • Severe hypernatremia with neurological symptoms.
  • Pulmonary edema, especially in patients with cardiac dysfunction.
  • Anaphylactoid reactions to solution components.
  • Metabolic acidosis or alkalosis from rapid shifts.
  • Hemolysis if solution is contaminated.

Precautions & Warnings

When using Natriumchlorid-Lösung Deltamedica, clinicians should observe several safety measures.

  • Assess fluid status: evaluate volume needs before infusion.
  • Monitor electrolytes: check serum sodium and chloride regularly.
  • Avoid rapid infusion: infuse at recommended rates to prevent cardiovascular stress.
  • Contraindicated in severe congestive heart failure: risk of fluid overload.
  • Use with caution in renal impairment: impaired excretion may exacerbate electrolyte disturbances.
  • Store at controlled room temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Sodium chloride solution may interact with other therapies that affect fluid and electrolyte balance.

Major Interactions (Avoid)

  • Concomitant hypertonic saline: can cause severe hypernatremia.
  • Potassium chloride infusions: risk of hypernatremia and electrolyte overload.
  • Diuretics that cause sodium loss: may counteract intended volume expansion.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may enhance potassium retention.
  • Other intravenous fluids: monitor total fluid volume to avoid overload.
  • Nephrotoxic agents: watch for compounded renal stress.
  • Corticosteroids: may affect sodium retention and blood pressure.

Frequently Asked Questions

Natriumchlorid-Lösung Deltamedica is an intravenous sodium chloride solution used to restore extracellular sodium and chloride levels, expand intravascular volume, and maintain electrolyte balance in patients requiring fluid replacement, such as those with hypovolemia, hyponatremia, or peri‑operative fluid loss.

When infused, sodium chloride delivers Na⁺ and Cl⁻ ions directly into the bloodstream, raising plasma osmolarity and volume. The added sodium helps retain water within the vascular compartment, while chloride supports acid‑base balance and electrical neutrality, together re‑establishing normal fluid distribution.

The appropriate dose is determined by the prescribing clinician based on the patient’s fluid status, electrolyte levels, and clinical condition. Dosing is individualized and should follow institutional protocols and physician orders.

Sodium chloride is a physiologic electrolyte and is generally considered compatible with pregnancy and lactation when used as directed. However, clinicians should assess maternal and fetal status and use the lowest effective volume to avoid fluid overload.

Enquiries can be submitted on the product page at gnhindia.com by specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Natriumchlorid-Lösung Deltamedica is an isotonic saline solution (0.9% NaCl) that provides balanced sodium and chloride without additional electrolytes or glucose. Compared with balanced solutions (e.g., Ringer's lactate), it lacks potassium, calcium, and lactate, making it suitable when those ions are contraindicated but less ideal for patients needing a more physiologic electrolyte mix.

Store the solution at controlled room temperature, typically below 25 °C. Keep the container sealed, protect it from moisture and direct sunlight, and ensure the vial or bag remains intact until use. Follow standard aseptic techniques during preparation and administration.

The product is administered intravenously. It can be given as a continuous infusion or intermittent bolus, depending on the clinical scenario and physician orders. Infusion sets and sterile technique must be used to maintain product integrity.

Serious risks include severe hypernatremia, pulmonary edema, and anaphylactoid reactions. These events are more likely in patients with cardiac or renal impairment, excessive infusion rates, or when combined with other sodium‑rich solutions. Continuous monitoring of fluid balance and electrolytes mitigates these risks.

Patients with severe congestive heart failure, uncontrolled hypertension, or renal failure who are at high risk for fluid overload should avoid routine use. Additionally, individuals with known hypersensitivity to the container or solution components should not receive the product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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