Product image of Nátrium-Klorid Aptapharma (Sodium Chloride) supplied by GNH India

Nátrium-Klorid Aptapharma

Active Ingredient:
Sodium Chloride
Origin:
EU

Nátrium-Klorid Aptapharma (Sodium Chloride)

Sodium chloride, the active ingredient in Nátrium-Klorid Aptapharma, is an electrolyte solution presented as an injection solution for intravenous use. It restores sodium and chloride levels and helps maintain osmotic balance in patients who require fluid and electrolyte replenishment, such as those with dehydration, blood loss, or electrolyte disturbances.

GNH India supplies Nátrium-Klorid Aptapharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Apta Medica Internacional D.O.O.

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Indications & Clinical Uses

Nátrium-Klorid Aptapharma, an intravenous electrolyte solution, is used to manage conditions involving fluid loss and electrolyte disturbances.

  • Fluid replacement: restores intravascular volume in patients with dehydration or acute blood loss.
  • Electrolyte imbalance correction: normalises serum sodium and chloride concentrations in hyponatraemic or hypochloraemic states.
  • Hypovolemia: supports circulatory volume in trauma, surgery or other causes of reduced plasma volume.

How It Works

  • Sodium chloride injection delivers Na+ and Cl‑ ions directly into the extracellular compartment, increasing plasma osmolarity. The rise in osmotic pressure draws water from the intracellular space into the vascular space, expanding intravascular volume and correcting sodium and chloride deficits. This osmotic shift helps re‑establish normal fluid distribution and electrolyte balance, supporting hemodynamic stability.

Side Effects

Common Side Effects

  • Injection site pain or erythema.
  • Phlebitis or mild local inflammation.
  • Mild hypernatremia.
  • Mild hyperchloremia.
  • Fluid overload presenting as peripheral edema.
  • Transient hypertension.

Serious or Rare Side Effects

  • Severe hypernatremia leading to neurological symptoms.
  • Hyperchloremic metabolic acidosis.
  • Pulmonary edema.
  • Anaphylactic or severe allergic reaction.
  • Cardiac arrhythmias secondary to electrolyte imbalance.
  • Severe hypotension from rapid volume shifts.

Precautions & Warnings

Before administration, assess the patient’s fluid status and electrolyte levels.

  • Assess volume status: evaluate fluid balance and signs of dehydration or overload.
  • Monitor electrolytes: check serum Na+ and Cl‑ concentrations during therapy.
  • Adjust infusion rate: tailor speed to avoid rapid osmotic shifts.
  • Contraindications: avoid in patients with existing hypernatremia or severe fluid overload.
  • Special populations: use caution in renal or cardiac failure patients.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Nátrium-Klorid Aptapharma may interact with other agents that affect fluid and electrolyte balance.

Major Interactions (Avoid)

  • Concomitant hypertonic saline: risk of severe hypernatremia.
  • Loop diuretics: may exacerbate electrolyte shifts.
  • ACE inhibitors: potential additive hypotension with volume expansion.

Moderate Interactions (Monitor Closely)

  • Other intravenous fluids (e.g., dextrose solutions): may alter overall electrolyte composition.
  • Systemic steroids: can influence fluid retention.
  • Blood product transfusions: require close electrolyte monitoring.

Frequently Asked Questions

Nátrium-Klorid Aptapharma is an intravenous sodium chloride solution used to replace lost fluids, correct electrolyte imbalances, and treat hypovolemia caused by dehydration, surgery, trauma, or bleeding. It provides sodium and chloride ions to restore plasma volume and maintain osmotic balance.

The product delivers sodium (Na+) and chloride (Cl‑) ions directly into the bloodstream. These ions increase extracellular osmolarity, drawing water from cells into the vascular compartment, which expands intravascular volume and corrects deficits in sodium and chloride, supporting normal fluid distribution and hemodynamic stability.

The dose of Nátrium-Klorid Aptapharma is determined by the prescribing clinician based on the patient’s fluid loss, electrolyte status, and clinical condition. The healthcare professional selects the appropriate concentration, volume, and infusion rate to safely achieve the desired therapeutic effect.

Safety data for sodium chloride injection in pregnancy and lactation are limited. It should only be used when clearly needed and prescribed by a qualified healthcare provider who can weigh the potential benefits against any possible risks to the mother and fetus or infant.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Nátrium-Klorid Aptapharma provides a pure sodium chloride formulation, offering precise control of Na+ and Cl‑ delivery. Compared with balanced electrolyte solutions that contain additional ions (e.g., potassium, calcium), it is useful when only sodium and chloride replacement is required, but may need supplementation if other electrolytes are deficient.

The product should be stored at 2‑8 °C, protected from light, and kept in its original packaging. Do not freeze or shake the vial. Before use, allow the solution to reach room temperature if necessary, and inspect for particulate matter or discoloration.

It is administered intravenously by slow infusion through a suitable IV line. The infusion rate is set by the prescribing clinician, often based on the patient’s hemodynamic status and the volume needed to correct fluid deficits. Monitoring during administration is recommended.

Serious risks include severe hypernatremia, hyperchloremic metabolic acidosis, pulmonary edema, and rare anaphylactic reactions. These events are more likely if the infusion is given too rapidly, in excessive volumes, or to patients with pre‑existing electrolyte disturbances or cardiac/renal impairment.

Patients with existing severe hypernatremia, marked fluid overload, or uncontrolled heart failure should avoid this product unless under strict medical supervision. Additionally, individuals with known hypersensitivity to sodium chloride solutions should not receive it.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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