Product image of Glucosalino Hiposódico (Sodium Chloride, Glucose) supplied by GNH India

Glucosalino Hiposódico

Active Ingredient:
Sodium Chloride, Glucose
Origin:
EU

Glucosalino Hiposódico (Sodium Chloride, Glucose)

Glucosalino Hiposódico is an intravenous solution that contains sodium chloride and glucose as its active ingredients. It is supplied in a sterile liquid form for parenteral administration, without a specified concentration on the label. The product is classified as a fluid and electrolyte replenisher and is marketed in the European Union. It requires a prescription and is used under medical supervision for fluid and electrolyte management.

Manufacturer / TM Owner

B.Braun Medical, S.A.

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Indications & Clinical Uses

Glucosalino Hiposódico is indicated for clinical situations where intravenous fluid replacement and electrolyte balance are required. It is commonly employed in the following contexts:

  • Perioperative hydration to maintain intravascular volume during surgery.
  • Treatment of mild to moderate dehydration from gastrointestinal losses.
  • Management of hypoglycemia by providing an immediate glucose source.
  • Electrolyte correction in patients with sodium chloride deficits.
  • Supportive therapy for patients unable to tolerate oral intake.
  • Fluid resuscitation in trauma patients with blood loss.
  • Adjunctive therapy during dialysis to prevent hypotension.

Side Effects

The intravenous administration of Glucosalino Hiposódico may be associated with a range of adverse reactions. Most events are mild and transient, while rare serious effects require medical attention. The frequency and severity of these events depend on patient condition, infusion rate, and total volume administered.

Common

  • Local irritation or pain at the infusion site.
  • Mild hypernatremia manifested by transient thirst.
  • Transient increase in blood glucose levels.
  • Mild electrolyte imbalance such as slight hypokalemia.
  • Mild metabolic acidosis due to infusion of chloride.
  • Transient increase in urine output (diuresis).

Serious

  • Severe hypernatremia leading to neurological symptoms.
  • Allergic reactions including rash, urticaria, or anaphylaxis.
  • Fluid overload causing pulmonary edema, especially in patients with cardiac dysfunction.

Precautions & Warnings

When using Glucosalino Hiposódico, clinicians should evaluate patient-specific factors and monitor for potential complications. Appropriate precautions help minimize risks associated with intravenous fluid therapy.

  • Assess serum electrolytes and glucose before initiating therapy.
  • Adjust infusion rate in patients with cardiac or renal impairment.
  • Avoid rapid administration in individuals at risk for cerebral edema.
  • Monitor fluid balance and signs of overload during treatment.
  • Use caution in patients with known hypersensitivity to sodium chloride or glucose solutions.
  • Re-evaluate therapy regularly in neonates and elderly patients.

Avoid Interactions

Glucosalino Hiposódico may interact with other intravenous solutions or medications that affect fluid and electrolyte balance. Consider the following interaction categories when planning therapy.

Avoid

  • Co-administration with hypertonic saline solutions that could cause severe hypernatremia.
  • Simultaneous infusion of large volumes of dextrose-containing fluids in patients at risk for hyperglycemia.

Use with caution

  • Concurrent use of diuretics, which may amplify electrolyte shifts.
  • Administration alongside nephrotoxic drugs, requiring close monitoring of renal function.
  • Combination with blood products, as rapid volume changes can affect hemodynamics.
  • Concurrent use with vasopressors may require adjustment of infusion rate to maintain target blood pressure.

Frequently Asked Questions

Glucosalino Hiposódico contains sodium chloride and glucose dissolved in a sterile aqueous solution for intravenous use.

The product is administered by intravenous infusion, typically through a peripheral or central venous catheter, under the supervision of a healthcare professional.

It is indicated for fluid replacement, electrolyte balance, treatment of hypoglycemia, perioperative hydration, and as supportive therapy when oral intake is not possible.

Use in pediatric patients should be based on clinical judgment, with careful monitoring of fluid status and electrolyte levels.

Monitoring should include vital signs, serum electrolytes, blood glucose, urine output, and signs of fluid overload or allergic reaction.

Common side effects include local infusion site irritation, mild hypernatremia, transient rise in blood glucose, and mild electrolyte disturbances.

The glucose component provides an immediate source of carbohydrate, raising blood glucose levels in patients experiencing hypoglycemia.

Compatibility depends on the specific medication; avoid mixing with hypertonic saline or large volumes of dextrose solutions without proper assessment.

Infusion rates should be reduced and fluid balance closely monitored to prevent fluid overload and electrolyte imbalances.

Store the solution at controlled room temperature, protected from light, and keep the container sealed until use.

Yes, it is commonly used for perioperative hydration to maintain intravascular volume and electrolyte balance during surgical procedures.

Stop the infusion immediately, notify a healthcare professional, and manage the reaction according to standard allergy protocols, which may include antihistamines or epinephrine.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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