Glucose 5% Com Cloreto De Sódio 0,9% Basi (Sodium Chloride, Glucose)

Glucose 5% and Sodium Chloride 0.9% Injection is indicated for several clinical situations where fluid, electrolyte, and energy support are required.

• Replacement of extracellular fluid losses due to surgery, trauma, or burns.
• Maintenance of hydration in patients unable to take oral fluids.
• Prevention or treatment of hypoglycemia when a rapid glucose source is needed.
• Electrolyte balance in patients receiving parenteral nutrition or diuretic therapy.
• Support during diagnostic or therapeutic procedures that require intravenous fluid administration.

Adverse reactions to the solution are generally related to the infusion itself or to the constituents.

Common

• Mild local irritation at the infusion site.
• Transient increase in blood glucose levels.
• Slight electrolyte shifts causing mild nausea or headache.
• Low-grade fever or chills during rapid infusion.
• Local phlebitis with redness and swelling.

Serious

• Hyperglycemia requiring medical intervention.
• Severe electrolyte imbalance such as hyponatremia or hypernatremia.
• Allergic reaction manifesting as rash, urticaria, or anaphylaxis.
• Fluid overload leading to pulmonary edema.
• Cardiovascular instability such as hypotension or arrhythmia.

Before using Glucose 5% and Sodium Chloride 0.9% Injection, clinicians should consider several precautionary measures to ensure patient safety.

• Assess blood glucose and electrolyte levels prior to initiation.
• Adjust infusion rate in patients with renal or cardiac impairment.
• Use caution in individuals with known hypersensitivity to any component.
• Monitor for signs of fluid overload, especially in elderly or critically ill patients.
• Avoid rapid bolus administration unless specifically indicated.
• Verify compatibility with other intravenous medications before co‑administration.
• Document the indication and volume administered in the patient record.

The solution may interact with certain drugs or clinical conditions; awareness of these interactions helps prevent complications.

Avoid

• Concurrent administration of high‑dose insulin without glucose supplementation.
• Use with hypertonic saline solutions that could exacerbate electrolyte disturbances.
• Mixing with drugs that are incompatible with chloride ions, such as certain calcium preparations.

Use with caution

• Concurrent diuretics that may alter sodium balance.
• Vasopressors that can affect peripheral circulation at the infusion site.
• Blood products, requiring separate lines to avoid precipitation.
• Medications that affect glucose metabolism, such as glucocorticoids.