Product image of Nátrium-Hidrogénkarbonát B.Braun (Sodium Hydrogen Carbonate) supplied by GNH India

Nátrium-Hidrogénkarbonát B.Braun

Active Ingredient:
Sodium Hydrogen Carbonate
Origin:
EU

Nátrium-Hidrogénkarbonát B.Braun (Sodium Hydrogen Carbonate)

Sodium Hydrogen Carbonate, the active ingredient in Nátrium-Hidrogénkarbonát B.Braun, is an alkali agent presented as a powder for oral use. It is employed to correct metabolic acidosis, neutralize gastric acid, and alkalinize urine in adult and pediatric patients when clinically indicated.

GNH India supplies Nátrium-Hidrogénkarbonát B.Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Customers benefit from consistent product availability and regulatory support across multiple regions.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Sodium Hydrogen Carbonate is used in several clinical situations that require systemic alkalinization or gastric acid neutralization.

  • Metabolic acidosis: restores normal blood pH by providing bicarbonate ions.
  • Hyperkalemia: promotes intracellular shift of potassium, helping to lower serum potassium levels.
  • Gastric acid excess: neutralizes stomach acid to relieve heartburn and dyspepsia.
  • Urinary alkalinization: increases urine pH to prevent precipitation of certain kidney stones and to enhance excretion of specific drugs.

How It Works

  • Sodium Hydrogen Carbonate dissociates in aqueous solution to release sodium and bicarbonate ions. The bicarbonate acts as a physiological buffer, combining with hydrogen ions to form carbonic acid, which is then converted to carbon dioxide and water, thereby raising systemic pH. The added sodium contributes to extracellular fluid volume and can influence electrolyte balance, supporting correction of acid‑base disturbances and neutralization of gastric acid.

Side Effects

Sodium Hydrogen Carbonate may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Nausea: mild stomach upset.
  • Vomiting: occasional episodes.
  • Abdominal discomfort: bloating or cramping.
  • Flatulence: increased intestinal gas.

Serious or Rare Side Effects

  • Severe metabolic alkalosis: excessive rise in blood pH requiring medical intervention.
  • Hypernatremia: elevated serum sodium leading to neurological symptoms.
  • Anaphylactic reaction: rare allergic response with rash, swelling, and breathing difficulty.

Precautions & Warnings

When prescribing Sodium Hydrogen Carbonate, clinicians should consider several precautionary measures to ensure patient safety.

  • Renal impairment: monitor serum electrolytes and acid‑base status.
  • Cardiac disease: caution due to added sodium load which may affect fluid balance.
  • Pregnancy and lactation: use only if clearly indicated after risk‑benefit assessment.
  • Concurrent acid‑lowering agents: assess for reduced efficacy or electrolyte disturbances.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Sodium Hydrogen Carbonate can alter the pharmacokinetics or pharmacodynamics of various medicines.

Major Interactions (Avoid)

  • Lithium therapy: increased lithium reabsorption may cause toxicity.
  • Cytotoxic agents requiring acidic urine (e.g., methotrexate): alkalinization can reduce drug efficacy.

Moderate Interactions (Monitor Closely)

  • Aspirin and other NSAIDs: may diminish antacid protective effect.
  • Antibiotics such as tetracyclines or fluoroquinolones: reduced absorption when taken with alkalinizing agents.
  • Diuretics: heightened risk of electrolyte imbalances, especially hypokalemia.

Frequently Asked Questions

Sodium Hydrogen Carbonate is employed to correct metabolic acidosis, neutralize excess gastric acid, and raise urinary pH. These actions make it useful in conditions such as severe acidosis, heartburn, dyspepsia, and prevention of certain kidney stones, as well as to facilitate the excretion of specific medications that require an alkaline environment.

After oral administration, Sodium Hydrogen Carbonate dissociates into sodium and bicarbonate ions. The bicarbonate buffers hydrogen ions, forming carbonic acid, which is rapidly converted to carbon dioxide and water, thereby increasing systemic pH. This buffering capacity corrects acidemia and neutralizes gastric acid, while the sodium component contributes to extracellular fluid balance.

The prescribed dose of Sodium Hydrogen Carbonate is individualized by the treating clinician based on the specific indication, severity of the acid‑base disturbance, patient weight, renal function, and concurrent medications. Dosage adjustments are made according to laboratory monitoring of blood pH, electrolytes, and clinical response.

Sodium Hydrogen Carbonate should be used in pregnancy or lactation only when clearly needed and after a careful risk‑benefit assessment by a healthcare professional. Limited data suggest it can be used for acute correction of metabolic acidosis, but unnecessary exposure should be avoided, and monitoring of maternal and fetal electrolyte status is recommended.

To request Nátrium-Hidrogénkarbonát B.Braun, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, and will ask for trade or institutional credentials. The sales team will then provide pricing, availability, shipping details (including any cold‑chain requirements), and assist with import documentation.

Sodium Hydrogen Carbonate provides rapid neutralization of gastric acid and systemic alkalinization, unlike calcium‑based antacids that primarily act locally. It delivers a higher sodium load, which can be advantageous for correcting metabolic acidosis but may be less suitable for patients requiring sodium restriction. Compared with magnesium or aluminum antacids, it has a lower risk of causing constipation or diarrhea.

Sodium Hydrogen Carbonate should be stored at ambient temperature, below 25 °C, in its original packaging. The container must be kept tightly closed to protect the powder from moisture and humidity, and it should be stored away from direct sunlight and sources of heat to maintain stability.

The product is supplied as a powder for oral use. It is typically reconstituted in water or another suitable liquid and ingested according to the dose prescribed by the clinician. Administration may be divided throughout the day, especially when used for chronic conditions, and should be taken with or without food as directed.

Serious risks include severe metabolic alkalosis, which can lead to respiratory depression, seizures, or cardiac arrhythmias, and hypernatremia, which may cause neurological symptoms such as confusion or coma. Rarely, anaphylactic reactions can occur, presenting with rash, swelling, and breathing difficulty, requiring immediate medical attention.

Patients with severe renal impairment, uncontrolled hypertension, or conditions requiring strict sodium restriction should avoid Sodium Hydrogen Carbonate unless specifically directed by a physician. Additionally, individuals with known hypersensitivity to sodium bicarbonate or related compounds should not use the product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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