Product image of Nefrosol Kálium B. Braun Avitum (Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc) supplied by GNH India

Nefrosol Kálium B. Braun Avitum

Active Ingredient:
Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc
Origin:
EU

Nefrosol Kálium B. Braun Avitum (Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc)

Sodium Hydrogen Carbonate, the active ingredient in Nefrosol Kálium B. Braun Avitum, is an electrolyte solution presented as an intravenous solution for intravenous use. It treats electrolyte depletion, metabolic acidosis, and fluid replacement in hospitalized patients.

GNH India supplies Nefrosol Kálium B. Braun Avitum as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

B.Braun Avitum Ag

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Indications & Clinical Uses

Nefrosol Kálium is an intravenous electrolyte solution used to correct disturbances in the electrolyte and acid‑base balance.

  • Electrolyte depletion: restores normal plasma concentrations of sodium, potassium, magnesium, calcium, and bicarbonate.
  • Metabolic acidosis: provides bicarbonate ions to help normalize blood pH.
  • Peri‑operative fluid replacement: maintains intravascular volume and electrolyte homeostasis during surgery.

How It Works

  • The solution delivers sodium, potassium, magnesium, calcium, and bicarbonate ions directly into the bloodstream. These ions replenish depleted electrolytes, support cellular function, and contribute to buffering capacity, thereby correcting acid‑base imbalances and sustaining intravascular volume during fluid loss or surgical procedures.

Side Effects

Adverse reactions may occur with any intravenous infusion. Monitoring and appropriate infusion rates reduce risk.

Common Side Effects

  • Infusion site irritation or phlebitis.
  • Mild hypernatremia.
  • Transient hyperkalemia.
  • Mild hypermagnesemia.
  • Mild hypocalcemia.
  • Fluid overload (edema).

Serious or Rare Side Effects

  • Severe hyperkalemia leading to cardiac arrhythmia.
  • Severe hypermagnesemia causing respiratory depression.
  • Anaphylactic or severe allergic reaction.
  • Rapid shifts in serum calcium resulting in tetany.
  • Severe fluid overload with pulmonary edema.
  • Metabolic alkalosis from excess bicarbonate.

Precautions & Warnings

Use Nefrosol Kálium with clinical monitoring and consider patient‑specific factors.

  • Renal impairment: adjust infusion rate and monitor electrolyte levels.
  • Cardiac disease: avoid rapid infusion that may provoke arrhythmias.
  • Hyperkalemia risk: assess baseline potassium before administration.
  • Fluid overload: limit volume in patients with heart failure.
  • Compatibility: verify compatibility with other IV solutions before mixing.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Electrolyte solutions can interact with other medications that affect ion balance.

Major Interactions (Avoid)

  • Concurrent potassium‑sparing diuretics: risk of dangerous hyperkalemia.
  • Calcium channel blockers with high calcium content: may cause hypercalcemia.
  • Sodium‑containing medications: can exacerbate hypernatremia.

Moderate Interactions (Monitor Closely)

  • Magnesium‑containing laxatives: increase risk of hypermagnesemia.
  • ACE inhibitors or ARBs: monitor renal function and potassium levels.
  • Anticoagulants: large volume infusion may affect coagulation parameters.

Frequently Asked Questions

Nefrosol Kálium is an intravenous electrolyte solution used to replace lost electrolytes and correct acid‑base disturbances such as metabolic acidosis. It is commonly administered in hospitals for patients with electrolyte depletion, during surgery for fluid balance, and in critical care settings where rapid electrolyte restoration is required.

Sodium Hydrogen Carbonate supplies bicarbonate ions that act as a physiological buffer, helping to raise blood pH toward normal levels. Together with potassium, magnesium, calcium, and sodium ions, it restores the electrolyte composition of plasma, supporting cellular function and maintaining hemodynamic stability.

The dose of Nefrosol Kálium is individualized by the prescribing clinician based on the patient’s electrolyte status, acid‑base balance, and clinical condition. The healthcare professional determines the infusion volume, rate, and duration according to laboratory values and therapeutic goals.

The safety of Nefrosol Kálium in pregnancy or lactation has not been definitively established. It should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by the treating physician after careful assessment.

To order Nefrosol Kálium, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Nefrosol Kálium provides a balanced combination of sodium, potassium, magnesium, calcium, and bicarbonate, making it suitable for a broad range of electrolyte and acid‑base disorders. Compared with simpler saline solutions, it offers additional ions that can correct metabolic acidosis and support cardiac and neuromuscular function without the need for multiple separate infusions.

Store Nefrosol Kálium at ambient temperature, preferably below 25 °C. Keep the container sealed, protect it from direct sunlight, and avoid exposure to moisture. Do not freeze the solution, and use it before the expiration date indicated on the packaging.

Nefrosol Kálium is administered intravenously. The solution is infused through a sterile IV line, typically using an infusion pump or controlled drip to achieve the prescribed rate. Administration should occur under clinical supervision with regular monitoring of vital signs and electrolyte levels.

Serious risks include severe hyperkalemia or hypermagnesemia, which can cause cardiac arrhythmias or respiratory depression, as well as anaphylactic reactions and rapid fluid overload leading to pulmonary edema. Prompt recognition of symptoms and immediate medical intervention are essential if these events occur.

Patients with known hypersensitivity to any component of the solution, uncontrolled hyperkalemia, severe renal failure without appropriate monitoring, or those at high risk for fluid overload (e.g., severe heart failure) should not receive Nefrosol Kálium unless a physician determines that benefits outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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