Product image of Nefrosol Fără Potasiu (Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Sodium Chloride, Calcium Chloride Dihydra) supplied by GNH India

Nefrosol Fără Potasiu

Active Ingredient:
Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Sodium Chloride, Calcium Chloride Dihydra
Origin:
EU

Nefrosol Fără Potasiu (Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Sodium Chloride, Calcium Chloride Dihydra)

Sodium hydrogen carbonate, magnesium chloride hexahydrate, sodium chloride, calcium chloride dihydrate, the active ingredient in Nefrosol Fără Potasiu, is an electrolyte solution presented as a solution for injection for intravenous use. It helps correct electrolyte and acid‑base imbalances in patients requiring fluid therapy.

GNH India supplies Nefrosol Fără Potasiu as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

B.Braun Avitum Ag

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Indications & Clinical Uses

Nefrosol Fără Potasiu is used as an intravenous electrolyte solution to address fluid and electrolyte disturbances.

  • Electrolyte replacement: restores sodium, chloride, magnesium and calcium levels in patients with deficits.
  • Metabolic acidosis correction: provides bicarbonate to buffer excess acidity.
  • Peri‑operative fluid management: maintains intravascular volume and electrolyte balance during surgery.
  • Trauma and shock resuscitation: supports circulatory volume and restores ion homeostasis.

How It Works

  • The solution delivers sodium, chloride, magnesium, calcium and bicarbonate ions directly into the bloodstream. Sodium and chloride re‑establish extracellular fluid osmolarity, magnesium and calcium support neuromuscular and cardiac function, while bicarbonate acts as a buffer to neutralize excess hydrogen ions, thereby correcting acid‑base disturbances and stabilising plasma electrolyte concentrations.

Side Effects

Nefrosol Fără Potasiu may be associated with the following adverse reactions.

Common Side Effects

  • Infusion site irritation: mild pain or redness at the injection site.
  • Mild hypernatremia: slight elevation of serum sodium levels.
  • Mild hypercalcemia: modest increase in calcium concentration.
  • Metabolic alkalosis: mild shift toward higher blood pH.

Serious or Rare Side Effects

  • Severe hypernatremia: marked sodium excess causing neurological symptoms.
  • Severe hypercalcemia: dangerous calcium elevation leading to cardiac arrhythmia.
  • Anaphylactic reaction: rare severe allergic response requiring immediate treatment.

Precautions & Warnings

When using Nefrosol Fără Potasiu, consider the following precautions.

  • Renal impairment: monitor electrolyte levels closely.
  • Cardiac disease: avoid rapid infusion rates.
  • Pregnancy: use only if clearly needed.
  • Concurrent potassium supplements: may exacerbate hypokalemia.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Nefrosol Fără Potasiu can interact with other medicines.

Major Interactions (Avoid)

  • Concurrent hypertonic saline: risk of severe hypernatremia.
  • Calcium channel blockers: may potentiate calcium load.
  • Loop diuretics: may cause rapid electrolyte shifts.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: monitor blood pressure and electrolyte balance.
  • Beta‑agonists: may affect calcium homeostasis.
  • Alkalinising antibiotics: may alter bicarbonate effect.

Frequently Asked Questions

Nefrosol Fără Potasiu is an intravenous electrolyte solution used to restore sodium, chloride, magnesium and calcium levels, correct metabolic acidosis, and provide fluid support during surgery, trauma or other conditions that cause electrolyte imbalance.

The formulation supplies essential ions—sodium, chloride, magnesium, calcium—and bicarbonate directly into the bloodstream. These ions re‑establish normal extracellular fluid composition, support cardiac and neuromuscular function, and the bicarbonate buffers excess acid, helping to normalize blood pH.

The appropriate dose is determined by the prescribing clinician based on the patient’s electrolyte status, fluid needs, and clinical condition. Dosage is individualized and administered intravenously under medical supervision.

Safety in pregnancy and lactation has not been fully established. It should be used only when clearly needed and after a risk‑benefit assessment by the treating physician.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Unlike solutions that contain potassium, Nefrosol Fără Potasiu is potassium‑free, making it suitable for patients where potassium restriction is required. It also includes magnesium and calcium, providing a broader ion profile compared with simple saline or bicarbonate solutions.

Store the solution at ambient temperature, preferably below 25 °C. Keep the vial in its original packaging, protect it from direct sunlight and moisture, and avoid freezing. Inspect for particulate matter before use.

The product is supplied as a sterile solution for injection and is administered intravenously. It may be given as a continuous infusion or intermittent bolus, according to the clinician’s prescription and the patient’s clinical status.

Serious risks include severe hypernatremia, severe hypercalcemia, anaphylactic reactions, and profound metabolic alkalosis, all of which can lead to neurological or cardiac complications. Prompt monitoring of electrolyte levels and patient response is essential.

Patients with known hypersensitivity to any component, uncontrolled hypernatremia or hypercalcemia, and those receiving incompatible intravenous solutions should not be given Nefrosol Fără Potasiu unless a physician determines the benefits outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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